Department of Biochemistry and Molecular Biophysics

Category: Frieden Publications

Dr. Frieden’s Publications

All Publications / Frieden Publications

APOE3-Jacksonville (V236E) variant reduces self-aggregation and risk of dementia

Chia-Chen Liu, Melissa E. Murray, Xia Li, Na Zhao, Na Wang, Michael G. Heckman, Francis Shue, Yuka Martens, Yonghe Li, Ana-Caroline Raulin, Cassandra L. Rosenberg, Sydney V. Doss, Jing Zhao, Melissa C. Wren, Lin Jia, Yingxue Ren, Tadafumi C. Ikezu, Wenyan Lu, Yuan Fu, Thomas Caulfield, Zachary A. Trottier, Joshua Knight, Yixing Chen, Cynthia Linares, Xue Wang, Aishe Kurti, Yan W. Asmann, Zbigniew K. Wszolek, Glenn E. Smith, Prashanthi Vemuri, Kejal Kantarci, David S. Knopman, Val J. Lowe, Clifford R. Jack Jr., Joseph E. Parisi, Tanis J. Ferman, Bradley F. Boeve, Neill R. Graff-Radford, Ronald C. Petersen, Steven G. Younkin, John D. Fryer, Hu Wang, Xianlin Han, Carl Frieden, Dennis W. Dickson, Owen A. Ross, & Guojun Bu (2021). “APOE3-Jacksonville (V236E) variant reduces self-aggregation and risk of dementia” Sci Transl Med. 2021 Sep 29;13(613):eabc9375. doi: 10.1126/scitranslmed.abc9375. Epub 2021 Sep 29. (Abstract)

All Publications / Frieden Publications

Functional insights from biophysical study of TREM2 interactions with apoE and Aβ 1-42

Daniel L. Kober, Melissa D. Stuchell-Brereton, Colin E. Kluender, Hunter B. Dean, Michael R. Strickland, Deborah F. Steinberg, Samantha S. Nelson, Berevan Baban, David M. Holtzman, Carl Frieden, Jennifer Alexander-Brett, Erik D. Roberson, Yuhua Song, & Tom J. Brett (2020). “Functional insights from biophysical study of TREM2 interactions with apoE and Aβ 1-42” Alzheimers Dement. 2020 Oct 8. doi: 10.1002/alz.12194. Online ahead of print. (Abstract)

All Publications / Frieden Publications

Bioorthogonal Chemistry Enables Single-Molecule FRET Measurements of Catalytically Active Protein Disulfide Isomerase

Mathivanan Chinnaraj, David A. Barrios, Carl Frieden, Tomasz Heyduk, Robert Flaumenhaft, & Nicola Pozzi. (2020). “Bioorthogonal Chemistry Enables Single-Molecule FRET Measurements of Catalytically Active Protein Disulfide Isomerase” Chembiochem. 2020 Aug 28. doi: 10.1002/cbic.202000537. Online ahead of print. (Abstract)

All Publications / DeKoster Publications / Frieden Publications

19 F NMR reveals the conformational properties of free thrombin and its zymogen precursor prethrombin-2

Eliza A. Ruben, Prafull S. Gandhi, Zhiwei Chen, Sarah K. Koester, Gregory T. DeKoster, Carl Frieden, & Enrico Di Cera. (2020). “19 F NMR reveals the conformational properties of free thrombin and its zymogen precursor prethrombin-2” J Biol Chem. 2020 Jun 12;295(24):8227-8235. doi: 10.1074/jbc.RA120.013419. Epub 2020 May 1. (Abstract)

All Publications / DeKoster Publications / Frieden Publications

Charge Reduction of Membrane Proteins in Native Mass Spectrometry Using Alkali Metal Acetate Salts

John T. Petroff 2nd, Ailing Tong, Lawrence J. Chen, Gregory T. Dekoster, Farha Khan, Jeff Abramson, Carl Frieden, & Wayland W. L. Cheng (2020). “Charge Reduction of Membrane Proteins in Native Mass Spectrometry Using Alkali Metal Acetate Salts” Anal Chem. 2020 May 5;92(9):6622-6630. doi: 10.1021/acs.analchem.0c00454. Epub 2020 Apr 14. (Abstract)

All Publications / Frieden Publications

Native Mass Spectrometry, Ion Mobility, Electron-Capture Dissociation, and Modeling Provide Structural Information for Gas-Phase Apolipoprotein E Oligomers.

Wang H., Eschweiler J., Cui W., Zhang H., Frieden C., Ruotolo B.T., & Gross M.L. (2019) “Native Mass Spectrometry, Ion Mobility, Electron-Capture Dissociation, and Modeling Provide Structural Information for Gas-Phase Apolipoprotein E Oligomers.” J Am Soc Mass Spectrom. 2019 Mar 18. doi: 10.1007/s13361-019-02148-z. [Epub ahead of print] (Abstract)

All Publications / Frieden Publications

Structure-Function Analysis of the Curli Accessory Protein CsgE Defines Surfaces Essential for Coordinating Amyloid Fiber Formation.

Klein R.D., Shu Q., Cusumano Z.T., Nagamatsu K., Gualberto N.C., Lynch A.J.L., Wu C., Wang W., Jain N., Pinkner J.S., Amarasinghe G.K., Hultgren S.J., Frieden C., & Chapman M.R. (2018). “Structure-Function Analysis of the Curli Accessory Protein CsgE Defines Surfaces Essential for Coordinating Amyloid Fiber Formation.” MBio. 2018 Jul 17;9(4). pii: e01349-18. doi: 10.1128/mBio.01349-18. (Abstract)

All Publications / Frieden Publications

Peptide-Level Interactions between Proteins and Small-Molecule Drug Candidates by Two Hydrogen-Deuterium Exchange MS-Based Methods: The Example of Apolipoprotein E3.

Wang H., Rempel D.L., Giblin D., Frieden C., & Gross M.L. (2017). “Peptide-Level Interactions between Proteins and Small-Molecule Drug Candidates by Two Hydrogen-Deuterium Exchange MS-Based Methods: The Example of Apolipoprotein E3.” Anal Chem. 2017 Oct 17;89(20):10687-10695. doi: 10.1021/acs.analchem.7b01121. Epub 2017 Sep 25. (Abstract)