Publications from the B&MB NMR Facility
 
 

 

2018

  • Weber, G., DeKoster, G.T., Holton, N., Hall, K.B., Wahl, M.C. Molecular Principles Underlying Dual RNA Specificity in the Drosophila SNF Protein. Nat. Commun. (2018)
  • Klein R.D., Shu, Q., Cusumano, Z.T., Nagamatsu, K., Gualberto, N.C., Lynch, A.J.L., Wu, C., Wang, W., Jain. N., Pinkner, J.S., Amarasinghe, G.K., Hultgren, S.J., Frieden, C., Chapman, M.R. Structure-Function Analysis of the Curli Accessory Protein CsgE Defines Surfaces Essential for Coordinating Amyloid Fiber Formation. M. Bio. (2018)

2017

  • Robinson, A.E., Thomas, N.E., Morrison, E.A., Balthazor, B.M., Henzler-Wildman, K.A. New Free-Exchange Model of EmrE Transport. P.N.A.S. (2017)
  • McCune, BT, Tang, W, Lu, J, Eaglesham, JB, Thorne, L, Mayer, AE, Condiff, E, Nice, TJ, Goodfellow, I, Krezel, AM, Virgin, HW. Noroviruses Co-opt the Function of Host Proteins VAPA and VAPB for Replication via a Phenylalanine-Phenylalanine-Acidic-Tract-Motif Mimic in Nonstructural Viral Protein NS1/2. M. Bio. (2017)

2016

  • Shu, Q., Krezel, A.M., Cusumano, Z.T., Pinkner, J.S., Klein, R., Hultgren, S.J., Frieden, C. Solution NMR Structure of CsgE: Structural Insights into a Chaperone and Regulator Protein Important for Functional Amyloid Formation. P.N.A.S. (2016)
  • Horvath, G., Bencsura, A., Simon, A., Tochtrop, G.P., DeKoster, G.T., Covey, D.F., Cistola, D.P., Toke, O. Structural Determinants of Ligand Binding in the Ternary Complex of Human Ileal Bile Acid Binding Protein with Glycocholate and Glycochenodeoxycholate obtained from Solution NMR. FEBS J. (2016)

2015

  • Brettmann, J.B., Urusovoa, D., Tonelli, M., Silva, J.R., Henzler-Wildman, K.A. Role of Protein Dynamics in Ion Selectivity and Allosteric Coupling in the NaK Channel. P.N.A.S. (2015)
  • Morrison, E.A., Robinson, A.E., Liu, Y., Henzler-Wildman, K.A. Assymmetric Protonation of EmrE. J. Gen. Physiol. (2015)
  • Rau, M.J., Welty, R., Stump, W.T., Hall, K.B. Formation of Tertiary Interactions during rRNA GTPase Center Folding. J. Mol. Biol. (2015)
  • Korasick, D.A., Chatterjee, S., Tonelli, M., Dashti, H., Lee, S.G., Westfall, C.S., Fulton, D.B., Amarasinghe, G.K., Strader, L.C., Jez, J.M. Defining a Two-Pronged Structural Model for PB1 (Phox/Bem1p) Domain Interaction in Plant Auxin Responses. J. Biol. Chem. (2015)

2014

  • DeKoster, G.T., Delaney, K.J., Hall, K.B. A Compare-and-Contrast NMR Dynamics Study of Two Related RRMs: U1A and SNF. Biophys. J. (2014)
  • Borin, B.N.,Tang, W.,McCune, B.T., Virgin, H.W., Krezel, A.M. Murine norovirus protein NS1/2 aspartate to glutamate mutation, sufficient for persistence, reorients side chain of surface exposed tryptophan within a novel structured domain. Proteins (2014)
  • Dutta, S., Morrison E.A, Henzler-Wildman K.A. Blocking Dynamics of the SMR Transporter EmrE Impairs Efflux Activity. Biophys. J. (2014)
  • Morrison E.A, Henzler-Wildman K.A. Transported Substrate Determines Exchange Rate in the Multidrug Resistance Transporter EmrE. J. Biol. Chem. 2014 Jan 21 (2014)
  • Batchelor J.D., Malpede B.M., Omattage N.S., DeKoster G.T., Henzler-Wildman K.A., Tolia N.H. Red Blood Cell Invasion by Plasmodium vivax: Structural Basis for DBP Engagement of DARC. PLoS Pathog. Jan;10(1):e1003869 (2014)
  • Hyde J.L., Gardner CL, Kimura T, White JP, Liu G, Trobaugh DW, Huang C, Tonelli M, Paessler S, Takeda K, Klimstra WB, Amarasinghe GK, Diamond MS. A Viral RNA Structural Element Alters Host Recognition of Nonself RNA. Science Jan. epub (2014)
  • Borin B.N., Tang W., Krezel A.M. Helicobacter pylori RNA Polymerase α-subunit C-terminal Domain Shows Features Unique to ε-proteobacteria and Binds NikR/DNA Complexes. Protein Science epub (2014)

2013

2012

  • Gonzalez-Perez V., Xu-Hui Z., Henzler-Wildman K.A., & Lingle C.J. Stereospecific Binding of a Disordered Peptide Segment Mediates BK Channel Inactivation. Nature 485:133-136 (2012)
  • Morrison, E.A., Henzler-Wildman, K.A. Reconstitution of Integral Membrane Proteins into Isotropic Bicelles with Improved Sample Stability and Expanded Lipid Composition Profile. Biochem. Biophys. Acta. 1818:814-20 (2012)

2011

  • Morrison, E.A., DeKoster, G.T., Dutta, S., Vafabakhsh, R., Clarkson, M.W., Bahl, A., Kern, D., Ha, T. & Henzler-Wildman, K.A. Antiparallel EmrE Exports Drugs by Exchanging Between Asymmetric Structures. Nature 481:45-50 (2011)

2010

  • Maynard, C.M., Hall, K.B. Interactions Between PTB RRMs Induce Slow Motions and Increase RNA Binding Affinity. J. Mol. Biol. 19:260-77 (2010)
  • Garai, K., Mustafi, S.M., Baban B., Frieden, C. Structural Differences Between Apolipoprotein E3 and E4 as Measured by (19)F NMR. Protein Sci. 19:66-74 (2010)

2009

  • Rajapaksha, M., Eichler, J.F., Hajduch, J., Anderson, D.E., Bann, J.G. Monitoring Anthrax Toxin Dissociation from the Protective Antigen by NMR. Protein Sci. 18:17-23 (2009)
  • Beck, M.R., DeKoster, G.T., Cistola, D.P. and Goldman, W.E. NMR Structure of a Fungal Virulence Factor Reveals Structural Homology with Mammalian Saposin B. Molecular Microbiology 72:344-353 (2009)
  • Cover Art 2009

2008

2007

  • Jastrzebska, I., Scaglione, J.B., DeKoster, G.T., Rath, R.P. and Covey, D.F. Palladium-Catalyzed Potassium Enoxyborate Alkylation of Enantiopure Hajos-Parrish Indenone to Construct Rearranged Steroid Ring Systems. J. Org. Chem. 72:4837-4843 (2007).

2006

  • Lu, J., Cistola, D.P. and Li, E. Analysis of ligand binding and protein dynamics of human retinoid X receptor alpha ligand-binding doman by nuclear magnetice resonance. Biochemistry 45:1629-1639 (2006).
  • Anderson, M.A., Ogbay, B., Arimoto, R., Sha, W., Kisselev, O.G. Cistola, D.P. and Marshall, G.R. Relative strength of cation-pi vs salt bridge interactions: The GTalpha(340-350) peptide/rhodopsin system. JACS 128:7531-7541 (2006).
  • Scaglione, J.B., Manion, B.D., Benz, A., Taylor, A., DeKoster, G.T., Rath, N.P., Evers, A.S., Zorumski, C.F., Mennerick, S., and Covey, D.F. Neurosteroid Analogues. 11. Alternative Ring System Scaffolds: Aminobutyric Acid Receptor Modulation and Anesthetic Actions of Benz[f]indenes. J. Med. Chem. 49:4595-4605 (2006).
  • Orsolya T., Monsey, J.D., DeKoster, G.T., Tochtrop, G.P., Tang, C., and Cistola, D.P. Determinants of Cooperativity and Site-Selectivity in Human Ileal Bile Acid Binding Protein. Biochemistry 45:727-37 (2006).

2005

  • Showalter, S.A. and Hall, K.B. Isotropic Reorientational Egenmode Dynamics Complements NMR Relaxation Measurements for RNA. Methods in Enzymology 394:465-480 (2005).
  • Showalter, S.A., Baker, N.A., Tang, C. and Hall, K.B. Iron Responsive Element RNA Flexibility Described by NMR and Isotropic Reorientational Egenmode Dynamics. Journal of Biomolecular NMR 32:179-193 (2005).
  • Li, H. and Frieden, C. Phenylalanine side chain behavior of the intestinal fatty acid binding protein: The effect of urea on backbone and side chain stability. J Biol Chem 280:38556-61(2005).
  • Shu, Q. and Frieden, C. Relation of enzyme activity of local/global stability of murine adenosine deaminase: 19F NMR studies. J Mol Biol 345:599-610 (2005).
  • Li, H. and Frieden, C. NMR studies of 4-(19)F-phenylalanine-labeled intestinal fatty acid binding protein: Evidence of conformational heterogeneity in the native state. Biochem 44:2369-2377 (2005).

2004

2003

  • Liu, W. Zheng, Y., Cistola, D.P. and Yang, D. Measurement of methyl 13C-1H cross-correlation in uniformly 13C-, 15N-, labeled proteins. Journal of Biomolecular NMR 27:351-364 (2003).
  • Lu, J., Cistola, D.P. and Li, E. Two homologous rat cellular retinol-binding proteins differ in local conformational flexibility. J Mol Biol 330:799-812 (2003).

2002

  • Michalski, M.L., Monsey, J.D., Cistola, D.P. and Weil, G.J. An embryo-associated fatty acid-binding protein in the filarial nematode Brugia malayi. Mol. Biochem. Parasitology 124:1-10 (2002).
  • Tochtrop, G.P., DeKoster, G.T., Cistola, D.P. and Covey, D.F. Synthesis of [3,4-(13)c(2)]-enriched bile salts as NMR probes of protein-ligand interactions. J Organic Chem. 67:6764-6771 (2002).
  • Tochtrop, G.P., DeKoster, G.T., Cistola, D.P. and Covey, D.F. A Simple Efficient Synthesis of [23,24]-13C(2)-Labeled Bile Salts as NMR Probes of Protein-Ligand Interactions. Bioorganic & Medicinal Chemistry Letters 12:433-435 (2002).
  • Tochtrop, G.P. Richter, K., Tang, C., Toner, J.J., Covey, D.F. and Cistola, D.P. Energetics by NMR: Site-specific binding in a positively cooperative system. Proceedings of the National Academy of Sciences of the United States of America 99:1847-52 (2002).
  • Bann, J.G., Pinkner, J., Hultgren, S.J. and Frieden, C. Real-time and equilibrium 19F-NMR studies reveal the role of domain-domain interactions in the folding of the chaperone PapD. Proc. Nat'l Acad Sci. 99:709-714 (2002).
  • Showalter, S.A. and Hall, K.B. A functional role for correlated motion in the N-terminal RNA-binding domain of human U1A protein. J Mol Biol 322:533-542 (2002).
  • Hall, K.B. RNA-protein interactions. Current Opinion in Structural Biology 12:282-288 (2002).

2000

  • Lu, J., Lin, C.-L., Tang, C., Ponder, J. W., Kao, J. L. F., Cistola, D. P. and Li, E. Binding of retinal induces changes in rat cellular retinal-binding protein II conformation and backbone dynamics. J. Mol. Biol. 300:619-632 (2000).