Faculty

Enrico Di Cera
Roy and Diana Vagelos Professor of Biochemistry and Molecular Biophysics
Professor of Medicine
Dept. of Biochemistry and
Molecular Biophysics

Office: 2915 South Building
Phone: 314-362-4185
Fax: 314-362-7183
Email: enrico@biochem.wustl.edu

Lab Website
Research Opportunities

Mailing Address:
WUSM - Biochemistry Dept.
660 S. Euclid Ave., MS8231
St. Louis, MO 63110

Papaconstantinou, M.E., Bah, A. and Di Cera, E. Role of the A chain in thrombin function. Cell Mol Life Sci. [Epub ahead of print] (2008)
Di Cera, E. Engineering protease specificity made simple, but not simpler. Nat Chem Biol 4:270-271 (2008)
Page, M.J., Carrell, C.J. and Di Cera, E. Engineering protein allostery: 1.05 A resolution structure and enzymatic properties of a Na(+)-activated trypsin. J Mol Biol. [Epub ahead of print] (2008).
Di Cera, E. Thrombin. Mol Aspects Med. (Epub ahead of print) (2008).
Nieman, M.T., Burke, F., Warnock, M., Zhou, Y., Sweigart, J., Chen, A., Ricketts, D., Lucchesi, B.R., Chen, Z., Di Cera, E., Hilfinger, J., Kim, J.S., Mosberg, H.I. and Schmaier, A.H. Thrombostatin FM compounds: Direct thrombin inhibitors - Mechanism of action in vitro and in vivo. J Thromb Haemost. (Epub ahead of print) (2008).
Page, M.J. and Di Cera, E. Serine peptidases: Classification, structure and function. Cell Mol Life Sci. 65:1220-1236 (2008).
Gandhi, P.S., Chen, Z., Mathews, F.S. and Di Cera, E. Structural identification of the pathway of long-range communication in an allosteric enzyme. Proc Natl Acad Sci U S A. 105:1832-1837 (2008).
Berny, M.A., White, T.C., Tucker, E.I., Bush-Pelc, L.A., Di Cera, E., Gruber, A. and McCarty, O.J. Thrombin mutant W215A/E217A acts as a platelet GPIb antagonist. Arterioscler Thromb Vasc Biol. 28:329-334(2008).