Faculty

Tom Ellenberger
Wittcoff Professor and Head
Dept. of Biochemistry and
Molecular Biophysics

Office: 2901 South Building
Phone: 314-362-0287
Fax: 314-362-4432
Email: tome@biochem.wustl.edu

Lab Website
Research Opportunities

Mailing Address:
WUSM - Biochemistry Dept.
660 S. Euclid Ave., MS8231
St. Louis, MO 63110

Chen, X., Zhong, S., Zhu, X., Dziegielewska, B., Ellenberger, T., Wilson, G.M., MacKerell, A.D. Jr and Tomkinson, A.E. Rational design of human DNA ligase inhibitors that target cellular DNA replication and repair. Cancer Res. 68:3169-3177 (2008).
Cotner-Gohara, E., Kim, I.K., Tomkinson, A.E. and Ellenberger, T. Two DNA binding and nick recognition modules in human DNA ligase III. J. Biol. Chem. (E-pub ahead of print.) (2008).
Tsodikov, O.V., Ivanov, D., Orelli, B., Staresincic, L, Shoshani, I., Oberman, R., Scharer, O.D., Wagner, G. and Ellenberger, T. Structural basis for the recruitment of ERCC1-XPF to nucleotide excision repair complexes by XPA. EMBO J. 26:4768-4776 (2007).
Aihara, H., Huang, W.M. and Ellenberger, T. An interlocked dimer of the Protelomerase TelK Distorts DNA Structure for the Formation of Hairpin Telemeres. Mol Cell. 27:901-913 (2007).
Ivanov, D., Tsodikov, O.V., Kasanov, J., Ellenberger, T., Wagner, G. and Colins, T. Domain-swapped dimerization of the HIV-1 capsid C-terminal domain. Proc Natl Acad Sci USA 104:4353-4358. (2007).
Wang, X., Kennedy, R., Ray, K., Stuckert, P., Ellenberger, T. and D' Andrea, A.D. Chk1-mediated phosphorylation of FANCE is required for the Fanconi anemia/BRCA pathway. Mol Cell Biol 27:3098-3108 (2007).
Kowal, P., Gurtan, A.M., Stuckert, P., D'Andrea, A.D. and Ellenberger, T. Structural determinants of human FANCF protein that function in the assembly of DNA damage signaling complex. J. Biol Chem 282:2047-2055 (2007).