Chivers Lab

Washington Universty in St. Louis - Department of Biochemistry and Molecular Biophyiscs

Selected Publications

Rowe, J. L., Starnes, G. L., and Chivers, P. T. Complex transcriptional control links NikABCDE-dependent nickel transport with hydrogenase expression in Escherichia coli. J. Bacteriol. 187, 6317-6323 (2005). Article Online

Wilbur, J. S., Chivers, P. T., Mattison, K., Potter, L., Brennan, R. G., and So, M. Neisseria gonorrhoeae FitA Interacts with FitB To Bind DNA through Its Ribbon-Helix-Helix Motif. Biochemistry 44, 12515 -12524 (2005). Article Online

Chivers, P. T. and Tahirov, T. H. Structure of Pyrococcus horikoshii NikR: nickel sensing and implications for the regulation of DNA recognition. J. Mol. Biol. 348, 597-607 (2005). Article Online

Setterdahl, A. T., Chivers, P. T., Hirasawa, M., Lemaire, S. D., Keryer, E., Miginiac-Maslow, M., Kim, S-K., Mason, J., Jacquot, J-P., Longbine, C. C., de Lamotte-Guery, F., and Knaff, D. B. The Effect of pH on the Oxidation-Reduction Properties of Thioredoxins. Biochemistry 42, 14877-14884 (2003). Article Online

Schreiter, E. D., Sintchak, M. D., Guo Y., Chivers, P. T., Sauer, R. T., and Drennan C. L. Crystal structure of the nickel-responsive transcription factor NikR Nat. Struct. Biol, 10, 794-799 (2003). Article Online

Carrington, Paul E., Chivers, Peter T., Al-Mjeni F., Sauer, Robert T., and Maroney, Michael J. (2003) Nickel coordination is regulated by the DNA-bound state of NikR. Nat. Struct. Biol. 10, 126-130. Article Online

Chivers, Peter T., and Sauer, Robert T. (2002) NikR repressor: high-affinity nickel binding to the C-terminal domain regulates binding to operator DNA. Chem. Biol. 9, 1141-1148. Article Online Download PDF

Schultz, L. Wayne, Chivers, Peter T., and Raines, Ronald T. (1999) The CXXC motif: crystal structure of an active-site variant of Escherichia coli thioredoxin. Acta Cryst. D55, 1533-1538. Article Online Download PDF

Chivers, Peter T., Laboissiere, Martha C. A., and Raines, Ronald T. (1998) Protein disulfide isomerase: cellular enzymology of the CXXC motif. In Prolyl 4-Hydroxylase, Protein Disulfide Isomerase, and Other Structurally Related Proteins, Norberto Guzman, ed. Marcel Dekker, Inc., New York, 1998. Article Online

Chivers, Peter T., and Raines, Ronald T. (1997) General acid/base catalysis in the active site of Escherichia coli thioredoxin. Biochemistry 36, 15810-15816. Article Online Download PDF

Chivers, Peter T., Prehoda, Kenneth E., and Raines, Ronald T. (1997) The CXXC motif: a rheostat in the active site. Biochemistry 36, 4061-4066. Article Online Download PDF

Chivers, Peter T., Laboissiere, Martha C. A., and Raines, Ronald T. (1996) The CXXC motif: imperatives for the formation of native disulfide bonds in the cell. EMBO J. 15, 2659-2667. Article Online

Laboissiere, Martha C. A., Chivers, Peter T., and Raines, Ronald T. (1995) Production of rat protein disulfide isomerase in Saccharomyces cerevisiae. Protein Expression and Purification 6, 700-706. Article Online

Huber, Reuben E., and Chivers, Peter T. (1993) b-Galactosidases of Escherichia coli with substitutions for Glu-461 can be activated by nucleophiles and can form b<-D-galactosyl adducts. Carbohydrate Research 250, 9-18. Article Online