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Membrane Protein Dynamics

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Cartoon of the multidrug resistance transporter EmrE converting between inward-facing and outward-facing conformations. Animation of the model proposed based on the antiparallel architecture of the crystal structure, PDB 3B5D and quasi-symmetry of the cryoEM structure (Chen et al., PNAS 104:18999, 2007; Fleishman, et al., JMB 364:54, 2006).
Movie constructed using maxsprout (www.ebi.ac.uk/maxsprout), pymol (pymol.sourceforge.net) and the Yale morph server (molmovdb.mbb.yale.edu/molmovdb/morph).