Biochemistry and Molecular Biophysics
Publications (PubMed / NIH)
We combine single-molecule fluorescence spectroscopy and concepts from polymer physics to investigate intrinsically disordered proteins; we develop innovative methods to study macromolecular conformations and dynamics within cells and in membraneless organelles.
Andrea Soranno, Franziska Zosel, & Hagen Hofmann (2018). “Internal friction in an intrinsically disordered protein—Comparing Rouse-like models with experiments” The Journal of Chemical Physics 148, 123326 (Abstract)
Franziska Zosel, Dominik Haenni, Andrea Soranno, Daniel Nettels, and Benjamin Schuler
Combining short- and long-range fluorescence reporters with simulations to explore the intramolecular dynamics of an intrinsically disordered protein
The Journal of Chemical Physics, Volume 147, Issue 15 (2017). (Abstract)
Schuler B., Soranno A., Hofmann H., and Nettels D.
Single-Molecule FRET Spectroscopy and the Polymer Physics of Unfolded and Intrinsically Disordered Proteins.
Annu Rev Biophys. 45:207-31 (2016) (Abstract)