Serine Proteases: Home Page

We are still working on this beta version of the web site. Tools and database extensions will be added and opened gradually until the end of August, the date of the first complete version. You can find more about the schedule in "what's next ?"

Serine Proteases

Tour

Introduction - Overview

Tutorials

Sequence Index

What's new

5 clans- 30 families - 700 sequences

What's next

Sequence Analyzer

Bugs & Stats

Make sequence sets - Align sequences - Analyze amino acid occurence

Evolution

Display amino acid occurence and filter specific positions through evolutionary trees

Mutations

Mutation catalog - Analyze position entropy - Correlate mutation effect and function

Structure Index

Select structures from sorted lists- Display imported PDB files in Chime or Rasmol

Structure Analyzer

Analyze structural features - Compare structures - Make scripts and display in Chime or Rasmol

Ligand Catalog & Analyzer

Catalogs of natural and synthetic substrates and inhibitors for selected proteases

Function

Track correlation of functions with sequences, structures or trees

Help

Help - References

MENU

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Go to the Department of Biochemistry and Molecular Biophysics

Thierry Rose, PhD and Enrico Di Cera, MD
Department of Biochemistry and Molecular Biophysics
Washington University School of Medicine
Saint Louis, MO, U.S.A.