FOCUS on RESEARCH
Dr. Tom Ellenberger's lab is working on nucleic enzymology, structural biology, macromolecular interactions and molecular recognition.
Dr. John Cooper’s lab studies molecular mechanisms of cell motility and cytoskeleton assembly.
Dr. Timothy Lohman's lab is working on equilibria and kinetics of DNA-protein interactions; DNA motor proteins (helicases) and helix destabilizing proteins.
Dr. Roberto Galletto's lab is working on the roles of DNA helicases in maintaining telomere structure.
Dr. Eric Galburt’s lab focuses on the use of single molecule biophysical approaches to study mechanistic aspects of eukaryotic transcription by RNA polymerase II and cotranscriptional RNA folding.
Dr. James Janetka's lab is working on medicinal chemistry, combinatorial and parallel synthesis and chemical biology.
Dr. Peter Burgers' lab is working on the biochemistry and genetics of yeast DNA replication and repair.
Dr. Kathleen Hall's lab is working on NMR and biochemical studies of RNA and RNA-protein complexes.
Dr. Greg Bowman's lab combines computer simulation and biochemical experiments to understand the role of proteins' conformational heterogeneity in antibiotic resistance and vision.
Dr. Carl Frieden's lab is working on protein folding, aggregation, intrinsically disordered proteins, fluorescence methods and fluorine NMR.
Dr. Weikai Li's lab is working on structural and biochemical studies of membrane proteins supporting blood coagulation.
Dr. Linda Pike's lab is working on mechanism of action of growth factors; polyphosphoinositide metabolism.
Michael S. Kinch and John A. Cooper, MD, PhD, professor and head of the Department of Biochemistry and Molecular Biophysics, will serve as co-directors of the new Center for Drug Discovery (CDD). The CDD will fill the void in developing drugs that have been abandoned due to market pressures. More…
Yansel Nuñez was recently awarded an NSF graduate fellowship. Yansel received a B.S. in biology from Seton Hall University. After graduation, he spent a year working at the NIH in their Intramural Research Training program. In 2014, he matriculated at Washington University in the Molecular Cell Biology graduate program. He joined Dr. Linda Pike’s laboratory where his thesis research focuses on EGF receptor structure and function.
ChemMedChem selected Dr. Laurel Mydock-McGrane’s image from the journal article, alpha-Ketobenzothiazole Serine Protease Inhibitors of Aberrant HGF/c-MET and MSP/RON Kinase Pathway Signaling in Cancer. Han, Z., Harris, P.K.W., Karmakar, P., Kim, T., Owusu, B.Y., Wildman, S.A., Klampfer, L. and Janetka, J.W. ChemMedChem 11:640 (2016) to be on the back cover of their March 17th issue. Dr. Mydock-McGrane is in the laboratory of Dr. Jim Janetka.
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