FOCUS on RESEARCH

BMB NEWS

Dr. Weikai Li featured in Nature Structural & Molecular Biology

Dr. Weikai LiThe January 2017 issue of Nature Structural & Molecular Biology is now available, and it features a News and Views piece highlighting Dr. Weikai Li’s recent publication, Warfarin traps human vitamin K epoxide reductase in an intermediate state during electron transfer.

You can view Dr. Weikai Li’s paper on NSMB’s site HERE (nature.com), or view the commentary on his paper HERE (nature.com).

Key drivers: Investments in basic science are fundamental to biomedical discovery.

School of Medicine investigators are harnessing new technologies to create precision and personalized approaches to diseases — advances that could not occur without prior investments in basic research.

“Basic research is a key driver of biomedical discovery and an essential part of the robust research environment at the School of Medicine,” said David H. Perlmutter, MD, executive vice chancellor for medical affairs and dean of the School of Medicine. (more…)

Novel approach shows promise against UTIs

Dr. Jim JanetkaA story about Jim Janetka’s research on antibiotic-sparing therapeutics, prompted by his new paper in J Med Chem, has just published in The Record. His research group has developed small molecules that prevent bacteria from sticking to the bladder wall, halting development of urinary tract infections in mice. (more…)

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BMB EVENTS

2016 SLU and WU Retreat

The SLU/WU Retreat was held on October 7, 2016 at the Danforth Plant Science Center.

Click the following links to view more photos or a slideshow of the photos taken at the event.

2016 Joint Department Welcome BBQ

On August 25, 2016, the Biochemistry Department and the Graduate Programs in Biochemistry and Computational & Molecular Biophysics hosted a welcome BBQ for the new incoming students.
The BBQ was held in Forest Park with food catered from Vernon’s BBQ. (Photos)

2nd Annual Chili Cook-off

On February 19th, we held our Annual Chili Cook-off. The competition was intense and the chili was good! The Lohman lab is this year’s winner. Congratulations! (Photos)

More in the Events Archive

 

Research Awards

  • December 19th, 2016 – Timothy M. Lohman, PhD, professor of biochemistry and molecular biophysics received a four year grant award from the National Institute of General Medical Sciences for his research entitled “Helicase Catalyzed DNA Unwinding”.

  • November 1st, 2016 – Dr. Gregory Bowman, Assistant Professor of Biochemistry and Molecular Biophysics received a two year subcontract from the National Institute of Allergy and Infectious Diseases. This project is a subcontract with Drs. Gaya Amarsinghe (Wash U) and Christopher Basler (Georgia State University) for his project entitled “Therapeutics Targeting Filoviral Interferon-Antagonist and Replication Functions”.

  • October 14th, 2016 – Dr. Gregory Bowman, Assistant Professor of Biochemistry and Molecular Biophysics, has been chosen to receive a 2016 Packard Fellowship for Science and Engineering in support of his research entitled “Energy-landscape engineering: exploiting proteins uncharted conformations”. (more…)

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Recent Publications

  • Galburt E.A. and Rammohan J.
    A Kinetic Signature for Parallel Pathways: Conformational Selection and Induced Fit. Links and Disconnects between Observed Relaxation Rates and Fractional Equilibrium Flux under Pseudo-First-Order Conditions.
    Biochemistry. 7014-7022. (2016) (Abstract)

  • Hayatshahi H.S., Roe D.R., Galindo-Murillo R., Hall K.B., and Cheatham T.E.
    Computational Assessment of Potassium and Magnesium Ion Binding to a Buried Pocket in the GTPase-Associating Center RNA.
    J Phys Chem B. (2016) (Abstract)

  • Garner A.L., Rammohan J., Huynh J.P., Onder L.M., Chen J., Bae B., Jensen D., Weiss L.A., Ruiz Manzano A., Darst S.A., Campbell E.A., Nickels B.E., Galburt E.A., and Stallings C.L.
    Effects of Increasing the Affinity of CarD for RNA Polymerase on Mycobacterium tuberculosis Growth, rRNA Transcription, and Virulence.
    J Bacteriol. (2016) (Abstract)

More Publications