Imaging /
Single Molecule Fluorescence Detection System Development
The
fluorescence imaging / single molecule detection system allows the study of
fluorescent samples under the microscope. Samples are scanned and then areas of
interest can be identified for further study. The changes in intensity with
time of these areas can be analyzed and compared by a variety of methods. Dual
APD detectors and easily configurable optics and light sources make possible
Fluorescence Correlation Spectroscopy (FCS) measurements, Cross-Correlation
measurements, FRET measurements, Anisotropy measurements, and Two-Photon Sample
Excitation on a variety of samples ranging from cells to single molecules.
Labview software is used to control the electronic components of the system
from a user-friendly graphical interface.
The
instrument is composed of the optical system, the scanning system, the photon
counting system, and the system software. To find out more about the
components, follow the links below.
Last updated August
10, 2003