Dr. Greg Bowman Awarded Tenure

The Board of Trustees voted at their May 3rd, 2019 meeting to award tenure in the Department of Biochemistry and Molecular Biophysics to Dr. Greg Bowman.

Josh Rackers selected as the 2019 Ceil M. DeGutis Prize Fellow

Josh Rackers

Josh Rackers is a graduate student in Biophysics at Washington University in St. Louis. His work focuses on using the tools of applied quantum mechanics to predict the behavior and interactions of biological molecules. This work is motivated by a deeply held belief that physics holds the answers to many of biology’s most important problems. Josh obtained a bachelor’s degree in Physics and Political Science from The Ohio State University. While at Ohio State, he performed research on Positron Emission Tomography (PET) silicon-based detector design. Following graduation, Josh decided that the most immediate way to make an impact on the world was to become a teacher. He was selected for Teach For America, an organization that places top university graduates in teaching positions at poor, mostly-urban schools. He taught high school physics and chemistry in Baltimore, Maryland in what was certainly the most difficult and rewarding job of his career. He claims to have succeeded in persuading a generation of students that physics really does matter to the real world. (more…)

Congratulations to Sukrit Singh for being selected for the 2019 MilliporeSigma Fellowship in memory of Dr. Gerty Cori

Sukrit is a graduate student in the Computational and Molecular Biophysics program. He is doing his PhD thesis work in the lab of Dr. Greg Bowman. Sukrit’s thesis is focused on understanding and exploiting allostery and dynamics in cellular signaling to develop anti-cancer therapeutics. (more…)

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2019 – Elson Fellowship Seminar

On February 22nd, 2019, the department held a special seminar to recognize the recipients of the 2017 Elliot Elson Fellowship. Ms. Min Kyung Shinn shared her research on “Assembly and Binding of E. coli RecOR Proteins to SSB C-terminal tails”. Mr. Drake Jensen shared his research on “Mechanisms of transcription represivation in Mycobacterium tuberculosis”. For more information on these two Elson fellows, please click here.

You can click here to view more photos from the event.

2018 BMB Holiday Party

CooperOn December 8th, 2018, the BMB Department celebrated its annual Holiday Party at Saratoga Lanes in Maplewood, MO. Everyone enjoyed bowling, pool and a visit from Santa.

Click on the following to view more photos or a slideshow of the photos taken at the event.

4th Annual Chili Cook-off (2018)

On October 26th, 2018, the BMB Department held our 4th Annual Chili Cook-off. Because of how close to Halloween it was being held, this year’s event also included a costume contest!

The winner with the best Chili was the Robertson lab! The Lohman lab won best costume – they all “dressed up” as Dr. Lohman!

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Research Awards

April 29th, 2019 – Andrea Soranno, PhD, Assistant Professor of Biochemistry and Molecular Biophysics received a new five year grant award from the National Institute on Aging for his research entitled “Conformational and functional analysis of Apolipoprotein E”.

January 31st, 2019 – Weikai Li, PhD, assistant professor of biochemistry and molecular biophysics, along with Michael L. Gross, PhD, professor of chemistry, immunology, and medicine, received a new four year grant award from the National Institute of General Medical Sciences for their research entitled “New chemical probes enable Mass Spectrometry-based footprinting of human protein structure in lipid membranes and cells”.

January 23rd, 2019 – Justin Porter, a Computational & Systems Biology student in the Bowman laboratory, received a three year National Research Service Award from the National Heart, Lung, and Blood Institute for his research entitled “Physics-based precision medicine: computationally phenotyping myosin isoforms and cardiomyopathy mutations”.

January 17th, 2019 – Andrea Soranno, PhD, Assistant Professor of Biochemistry and Molecular Biophysics received a new three year Research Grant Award from the Alzheimer’s Association (AARG) for his work entitled “Conformational analysis of ApoE isoforms and their role in AD mechanism”.

January 9th, 2019 – Weikai Li, PhD, assistant professor of biochemistry and molecular biophysics received a four year renewal from the National Heart, Lung, and Blood Institute for his research entitled “Structural and Functional Basis of the Vitamin K Cycle”.

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Recent Publications

Damalanka V.C. & Janetka J.W. (2019). “Recent progress on inhibitors of the type II transmembrane serine proteases, hepsin, matriptase and matriptase-2.” Future Med Chem. 2019 Apr 4. doi: 10.4155/fmc-2018-0446. [Epub ahead of print] (Abstract)

Michael Kinch (2019). “The End of the Beginning: Cancer, Immunity, and the Future of a Cure” ISBN-13: 978-1643130255, ISBN-10: 1643130250

Wang H., Eschweiler J., Cui W., Zhang H., Frieden C., Ruotolo B.T., & Gross M.L. (2019) “Native Mass Spectrometry, Ion Mobility, Electron-Capture Dissociation, and Modeling Provide Structural Information for Gas-Phase Apolipoprotein E Oligomers.” J Am Soc Mass Spectrom. 2019 Mar 18. doi: 10.1007/s13361-019-02148-z. [Epub ahead of print] (Abstract)

Tomko E.J. & Galburt E.A. (2019). “Single-molecule approach for studying RNAP II transcription initiation using magnetic tweezers.” Methods. 2019 Mar 18. pii: S1046-2023(18)30297-4. doi: 10.1016/j.ymeth.2019.03.010. [Epub ahead of print] (Abstract)

Porter J.R., Moeder K.E., Sibbald C.A., Zimmerman M.I., Hart K.M., Greenberg M.J., & Bowman G.R. (2019). “Cooperative Changes in Solvent Exposure Identify Cryptic Pockets, Switches, and Allosteric Coupling.” Biophys J. 2019 Mar 5;116(5):818-830. doi: 10.1016/j.bpj.2018.11.3144. Epub 2019 Jan 25. (Abstract)

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