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BMB NEWS

Congratulations to Dr. Pike and Dr. Hall!

PikeHall

Dr. Linda Pike and Dr. Kathleen Hall have been selected as new fellows by the American Association for the Advancement of Science (AAAS), the world’s largest general scientific society.

The AAAS selects fellows in recognition of their distinguished efforts to advance science and its applications, and has selected eleven faculty members at Washington University in St. Louis – the most in a decade-and-a-half. (more…)

Dr. Pike Awarded Professor of the Year

linda_pikeOn November 15th, the Distinguished Service Teaching Awards ceremony was to honor faculty that exhibited exemplary teaching skills from the 2017-2018 school year. The Class of 2021 awarded Dr. Linda Pike with Professor of the Year. Congratulations Dr. Pike!

Congratulations to Sarah Clippinger for being selected for the 2018 Elson Fellowship in honor of Dr. Elliot Elson

sarah_clippingerMs. Sarah Clippinger received her B.S. in Biochemistry from the Ohio State University in 2016. After graduation, Ms. Clippinger joined the Division of Biological and Biomedical Sciences at Washington University in St. Louis as part of the Biochemistry, Biophysics and Structural Biology program. (more…)

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BMB EVENTS

2018 BMB Holiday Party

CooperOn December 8th, 2018, the BMB Department celebrated its annual Holiday Party at Saratoga Lanes in Maplewood, MO. Everyone enjoyed bowling, pool and a visit from Santa.

Click on the following to view more photos or a slideshow of the photos taken at the event.

4th Annual Chili Cook-off (2018)

On October 26th, 2018, the BMB Department held our 4th Annual Chili Cook-off. Because of how close to Halloween it was being held, this year’s event also included a costume contest!

The winner with the best Chili was the Robertson lab! The Lohman lab won best costume – they all “dressed up” as Dr. Lohman!
(more…)

John Majors Symposium

On Friday, October 19th, 2018, a symposium in remembrance of Dr. John Majors was held in Moore Auditorium on the medical campus of Washington University. Many colleagues, friends and family members from the university community, as well as from across the country, were in attendance. Drs. Peter Burgers, Mark Johnston, Charlie Rice, and Harold Varmus all gave heartfelt talks about John’s influence in biophysics as well as speaking about the different hobbies (i.e., backpacking and golf) and interests John had outside of the lab. It was great to hear about the many sides of John that were not widely known. By the end of the day, everyone had learned something new about John. (more…)

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Research Awards

January 17th, 2019 – Andrea Soranno, PhD, Assistant Professor of Biochemistry and Molecular Biophysics received a new three year Research Grant Award from the Alzheimer’s Association (AARG) for his work entitled “Conformational analysis of ApoE isoforms and their role in AD mechanism”.

January 9th, 2019 – Weikai Li, PhD, assistant professor of biochemistry and molecular biophysics received a four year renewal from the National Heart, Lung, and Blood Institute for his research entitled “Structural and Functional Basis of the Vitamin K Cycle”.

December 27th, 2018 – Weikai Li, PhD, assistant professor of biochemistry and molecular biophysics, along with Rui Zhang, PhD, assistant professor of biochemistry and molecular biophysics received a new three year, grant award from the W. M. Keck foundation for their research entitled “Terminal coupling enabled structure determination of human membrane proteins at atomic resolution”.

October 19th, 2018 – Andrea Soranno, PhD, Assistant Professor of Biochemistry and Molecular Biophysics received a New Investigator Award in Alzheimer’s Disease from the American Federation for Aging Research (AFAR), Inc. for his work entitled “Identifying Neurotoxic Conformers in the Structural Ensemble of apoE”.

May 2nd, 2018 – Andrea Soranno, PhD, Assistant Professor of Biochemistry and Molecular Biophysics received a Knight ADRC Pilot Grant award from the Alzheimer’s Disease Research Center (ADRC) for his work entitled “Conformational analysis of ApoE and its role in AD mechanism”.

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Recent Publications

Knoverek C.R., Amarasinghe G.K., & Bowman G.R. (2018). “Advanced Methods for Accessing Protein Shape-Shifting Present New Therapeutic Opportunities.” Trends Biochem Sci. 2018 Dec 13. pii: S0968-0004(18)30248-2. doi: 10.1016/j.tibs.2018.11.007. [Epub ahead of print] (Abstract)

Maddirala A., Klein R.D., Pinkner J., Kalas V., Hultgren S.J., & Janetka J.W. (2018). “Biphenyl Gal and GalNAc FmlH Lectin Antagonists of Uropathogenic E. coli (UPEC): Optimization through iterative rational drug design.” J Med Chem. 2018 Dec 12. doi: 10.1021/acs.jmedchem.8b01561. [Epub ahead of print] (Abstract)

Dubiel K., Myers A.R., Kozlov A.G., Yang O., Zhang J., Ha T., Lohman T.M., & Keck J.L. (2018). “Structural Mechanisms of Cooperative DNA Binding by Bacterial Single-Stranded DNA-Binding Proteins.” J Mol Biol. 2018 Nov 22. pii: S0022-2836(18)31046-5. doi: 10.1016/j.jmb.2018.11.019. [Epub ahead of print] (Abstract)

Galburt E.A. (2018). “The calculation of transcript flux ratios reveals single regulatory mechanisms capable of activation and repression.” Proc Natl Acad Sci U S A. 2018 Nov 21. pii: 201809454. doi: 10.1073/pnas.1809454115. [Epub ahead of print] (Abstract)

Zimmerman M.I., Porter J.R., Sun X., Silva R.R., & Bowman G.R. (2018). “Choice of Adaptive Sampling Strategy Impacts State Discovery, Transition Probabilities, and the Apparent Mechanism of Conformational Changes.” J Chem Theory Comput. 2018 Nov 13;14(11):5459-5475. doi: 10.1021/acs.jctc.8b00500. Epub 2018 Oct 23. (Abstract)

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