Esterase mutation is a mechanism of resistance to antimalarial compounds.

Istvan E.S., Mallari J.P., Corey V.C., Dharia N.V., Marshall G.R., Winzeler E.A., and Goldberg D.E. (2017) “Esterase mutation is a mechanism of resistance to antimalarial compounds.” Nat Commun. 2017 Jan 20;8:14240. doi: 10.1038/ncomms14240. (Abstract)