Ana Ruiz Manzano, Ph.D.

Ana Ruiz Manzano
Assistant Professor

Biochemistry and Molecular Biophysics

Lab Website

Office: 251 McDonnell Science Building
Phone: 314-362-4821
Email: aruizmanzano@wustl.edu
 

Research

Select Publications

Drake Jensen, Ana Ruiz Manzano, Maxwell Rector, Eric J Tomko, M Thomas Record, & Eric A Galburt (2023). “High-throughput, fluorescent-aptamer-based measurements of steady-state transcription rates for the Mycobacterium tuberculosis RNA polymerase” J Cell Biol. 2024 Jan 1;223(1):e202312031. doi: 10.1083/jcb.202312031. Epub 2023 Dec 12. (Abstract)

Jensen D., Ruiz Manzano A., Rammohan J., Stallings C.L., & Galburt E.A. (2019). “CarD and RbpA modify the kinetics of initial transcription and slow promoter escape of the Mycobacterium tuberculosis RNA polymerase.” Nucleic Acids Res. 2019 May 25. pii: gkz449. doi: 10.1093/nar/gkz449. [Epub ahead of print] (Abstract)

Drake Jensen, Ana Ruiz Manzano, Christina L. Stallings, & Eric A. Galburt. (2019). “Regulation of Mycobacterial RNA Polymerase Promoter Escape Kinetics by Transcription Factors Card and RbpA” Biophysical Journal. Volume 116, Issue 3, Supplement 1, 15 February 2019, Page 210a. (Abstract)

Prusa J., Jensen D., Santiago-Collazo G., Pope S.S., Garner A.L., Miller J.J., Ruiz Manzano A., Galburt E.A., & Stallings C.L. (2018). “Domains within RbpA serve specific functional roles that regulate the expression of distinct mycobacterial gene subsets.” J Bacteriol. 2018 Apr 23. pii: JB.00690-17. doi: 10.1128/JB.00690-17. (Abstract)

Garner A.L., Rammohan J., Huynh J.P., Onder L.M., Chen J., Bae B., Jensen D., Weiss L.A., Ruiz Manzano A., Darst S.A., Campbell E.A., Nickels B.E., Galburt E.A., & Stallings C.L. (2016). “Effects of Increasing the Affinity of CarD for RNA Polymerase on Mycobacterium tuberculosis Growth, rRNA Transcription, and Virulence.” J Bacteriol. 2017 Jan 30;199(4). pii: e00698-16. doi: 10.1128/JB.00698-16. Print 2017 Feb 15. (Abstract)