The following is a partial list of publications by faculty, post-doctoral associates, students, and staff of Biochemistry and Molecular Biophysics.
Jiyeon Lee, Julie M Dimitry, Jong Hee Song, Minsoo Son, Patrick W Sheehan, Melvin W King, G Travis Tabor, Young Ah Goo, Mitchell A Lazar, Leonard Petrucelli, Erik S Musiek (2023). “Microglial REV-ERBα regulates inflammation and lipid droplet formation to drive tauopathy in male mice” Nat Commun. 2023 Aug 25;14(1):5197. doi: 10.1038/s41467-023-40927-1. (Abstract)
Abhay K Singh, Calvin D Lewis, Cristian A W V Boas, Philipp Diebolder, Prashant N Jethva, Aaron Rhee, Jong Hee Song, Young Ah Goo, Shunqian Li, Michael L Nickels, Yongjian Liu, Buck E Rogers, Vaishali Kapoor & Dennis E Hallahan (2024). “Development of a [89Zr]Zr-labeled Human Antibody using a Novel Phage-displayed Human scFv Library” Clin Cancer Res. 2024 Apr 1;30(7):1293-1306. doi: 10.1158/1078-0432.CCR-23-3647. (Abstract)
Tusar Giri, Susan E Maloney, Saswat Giri, Young Ah Goo, Jong Hee Song, Minsoo Son, Eric Tycksen, Sara B Conyers, Annie Bice, Xia Ge, Joel R Garbow, James D Quirk, Adam Q Bauer & Arvind Palanisamy (2024). “Oxytocin-induced birth causes sex-specific behavioral and brain connectivity changes in developing rat offspring” iScience. 2024 Jan 22;27(2):108960. doi: 10.1016/j.isci.2024.108960. eCollection 2024 Feb 16. (Abstract)
Meaghan S Jankowski, Daniel Griffith, Divya G Shastry, Jacqueline F Pelham, Garrett M Ginell, Joshua Thomas, Pankaj Karande, Alex S Holehouse & Jennifer M Hurley (2024). “Disordered clock protein interactions and charge blocks turn an hourglass into a persistent circadian oscillator” Nat Communn. 2024 Apr 25;15(1):3523. doi: 10.1038/s41467-024-47761-z. (Abstract)
Zongru Li, Qionghua Shen, Emery T Usher, Andrew P Anderson, Manuel Iburg, Richard Lin, Brandon Zimmer, Matthew D Meyer, Alex S Holehouse, Lingchong You, Ashutosh Chilkoti, Yifan Dai & George J Lu (2024). “Phase transition of GvpU regulates gas vesicle clustering in bacteria” Nat Microbiol. 2024 Apr;9(4):1021-1035. doi: 10.1038/s41564-024-01648-3. Epub 2024 Mar 29. (Abstract)
S Sanchez-Martinez, K Nguyen, S Biswas, V Nicholson, A V Romanyuk, J Ramirez, S Kc, A Akter, C Childs, E K Meese, E T Usher, G M Ginell, F Yu, E Gollub, M Malferrari, F Francia, G Venturoli, E W Martin, F Caporaletti, G Giubertoni, S Woutersen, S Sukenik, D N Woolfson, A S Holehouse & T C Boothby (2024). “Labile assembly of a tardigrade protein induces biostasis” Protein Sci.2024 Apr;33(4):e4941. doi: 10.1002/pro.4941. (Abstract)
Jeffrey M Lotthammer, Garrett M Ginell, Daniel Griffith, Ryan J Emenecker & Alex S Holehouse (2024). “Direct prediction of intrinsically disordered protein conformational properties from sequence” Nat Methods. 2024 Mar;21(3):465-476. doi: 10.1038/s41592-023-02159-5. Epub 2024 Jan 31. (Abstract)
Sourav Biswas, Edith Gollub, Feng Yu, Garrett Ginell, Alex Holehouse, Shahar Sukenik & Thomas C Boothby 1 (2024). “Helicity of a tardigrade disordered protein contributes to its protective function during desiccation” Protein Sci. 2024 Feb;33(2):e4872. doi: 10.1002/pro.4872. (Abstract)
David Moses, Karina Guadalupe, Feng Yu, Eduardo Flores, Anthony R Perez, Ralph McAnelly, Nora M Shamoon, Gagandeep Kaur, Estefania Cuevas-Zepeda, Andrea D Merg, Erik W Martin, Alex S Holehouse & Shahar Sukenik (2024). “Structural biases in disordered proteins are prevalent in the cell” Nat Struct Mol Biol. 2024 Feb;31(2):283-292. doi: 10.1038/s41594-023-01148-8. Epub 2024 Jan 4. (Abstract)
Alex S Holehouse & Birthe B Kragelund (2024). “The molecular basis for cellular function of intrinsically disordered protein regions” Nat Rev Mol Cell Biol. 2024 Mar;25(3):187-211. doi: 10.1038/s41580-023-00673-0. Epub 2023 Nov 13. (Abstract)
Priya R Banerjee, Alex S Holehouse, Richard Kriwacki, Paul Robustelli, Hao Jiang, Alexander I Sobolevsky, Jennifer M Hurley & Joshua T Mendell (2024). “Dissecting the biophysics and biology of intrinsically disordered proteins” Trends Biochem Sci. 2024 Feb;49(2):101-104. doi: 10.1016/j.tibs.2023.10.002. Epub 2023 Nov 8. (Abstract)
David Moses, Garrett M Ginell, Alex S Holehouse & Shahar Sukenik (2023). “Intrinsically disordered regions are poised to act as sensors of cellular chemistry” Trends Biochem Sci. 2023 Dec;48(12):1019-1034. doi: 10.1016/j.tibs.2023.08.001. Epub 2023 Aug 31. (Abstract)
Karol Buda, Katerina Cermakova, H Courtney Hodges, Eugenio F Fornasiero, Shahar Sukenik & Alex S Holehouse (2023). “Using graphs and charts in scientific figures” Trends Biochem Sci. 2023 Nov;48(11):913-916. doi: 10.1016/j.tibs.2023.08.011. (Abstract)
Gretchen A Meyer, Jeremie L A Ferey, James A Sanford, Liam S Fitzgerald, Akiva E Greenberg, Kristoffer Svensson, Michael J Greenberg & Simon Schenk (2024). “Insights into posttranslational regulation of skeletal muscle contractile function by the acetyltransferases, p300 and CBP” J Appl Physiol (1985). 2024 Jun 1;136(6):1559-1567. doi: 10.1152/japplphysiol.00156.2024. Epub 2024 May 9. (Abstract)
Venecia Valdez, Meisheng Ma, Bernardo Gouveia, Rui Zhang & Sabine Petry (2024). “HURP facilitates spindle assembly by stabilizing microtubules and working synergistically with TPX2” bioRxiv. [Preprint]. 2023 Dec 18:2023.12.18.571906. doi: 10.1101/2023.12.18.571906. (Abstract)
Kiarash Jamali, Lukas Käll, Rui Zhang, Alan Brown, Dari Kimanius & Sjors H W Scheres (2024). “Automated model building and protein identification in cryo-EM maps” Nature. 2024 Apr;628(8007):450-457. doi: 10.1038/s41586-024-07215-4. Epub 2024 Feb 26. (Abstract)
Ankit Garg, Silvia Jansen, Rui Zhang, Kory J Lavine & Michael J Greenberg (2024). “Dilated cardiomyopathy-associated skeletal muscle actin (ACTA1) mutation R256H disrupts actin structure and function and causes cardiomyocyte hypocontractility” bioRxiv. [Preprint]. 2024 Mar 12:2024.03.10.583979. doi: 10.1101/2024.03.10.583979. (Abstract)
Steven L Brody, Jiehong Pan, Tao Huang, Jian Xu, Huihui Xu, Jeffrey Koenitizer, Steven K Brennan, Rashmi Nanjundappa, Thomas G Saba, Andrew Berical, Finn J Hawkins, Xiangli Wang, Rui Zhang, Moe R Mahjoub, Amjad Horani & Susan K Dutcher (2024). “Loss of an extensive ciliary connectome induces proteostasis and cell fate switching in a severe motile ciliopathy” bioRxiv. [Preprint]. 2024 Mar 21:2024.03.20.585965. doi: 10.1101/2024.03.20.585965. (Abstract)
Jin Dai, Meisheng Ma, Qingwei Niu, Robyn J Eisert, Xiangli Wang, Poulomi Das, Karl F Lechtreck, Susan K Dutcher, Rui Zhang & Alan Brown (2024). “Mastigoneme structure reveals insights into the O-linked glycosylation code of native hydroxyproline-rich helices” Cell. 2024 Apr 11;187(8):1907-1921.e16. doi: 10.1016/j.cell.2024.03.005. Epub 2024 Mar 28. (Abstract)
Gabor Egervari, Desi C. Alexander, Greg Donahue, Hua Huang, Connor Hogan, Mariel Mendoza, Benjamin A. Garcia, Nancy M. Bonini, Shelley L. Berger (2024). “ACSS2 contributes to transcriptional regulation in Cajal-Retzius cells in a mouse model of Alzheimer’s disease” bioRxiv. [Preprint] (Abstract)
Jasmine Cubuk, Lina Greenberg, Akiva E Greenberg, Ryan J Emenecker, Melissa D Stuchell-Brereton, Alex S Holehouse, Andrea Soranno & Michael J Greenberg (2024). “Structural dynamics of the intrinsically disordered linker region of cardiac troponin T” bioRxiv. [Preprint]. 2024 May 31:2024.05.30.596451. doi: 10.1101/2024.05.30.596451. (Abstract)
Eva Fortea, Sangyun Lee, Rahul Chadda, Yiorgos Argyros, Priyanka Sandal, Robyn Mahoney-Kruszka, Hatice Didar Ciftci, Maria E Falzone, Gerard Huysmans, Janice L Robertson, Olga Boudker & Alessio Accardi (2024). “Structural basis of pH-dependent activation in a CLC transporter” Nat Struct Mol Biol. 2024 Apr;31(4):644-656. doi: 10.1038/s41594-023-01210-5. Epub 2024 Jan 26. (Abstract)
Melanie Ernst, Esam A Orabi, Randy B Stockbridge, José D Faraldo-Gómez & Janice L Robertson (2023). “Dimerization mechanism of an inverted-topology ion channel in membranes” Proc Natl Acad Sci U S A. 2023 Nov 21;120(47):e2308454120. doi: 10.1073/pnas.2308454120. Epub 2023 Nov 13. (Abstract)
Jasmine Cubuk, Jhullian J Alston, J Jeremías Incicco, Alex S Holehouse, Kathleen B Hall, Melissa D Stuchell-Brereton & Andrea Soranno (2024). “The disordered N-terminal tail of SARS-CoV-2 Nucleocapsid protein forms a dynamic complex with RNA” Nucleic Acids Res. 2024 Mar 21;52(5):2609-2624. doi: 10.1093/nar/gkad1215. (Abstract)
Melanie Ernst, Tugba N Ozturk, Janice L Robertson (2023). “A single-molecule method for measuring fluorophore labeling yields for the study of membrane protein oligomerization in membranes” PLoS One. 2023 Jan 20;18(1):e0280693. doi: 10.1371/journal.pone.0280693. eCollection 2023. (Abstract)
Rahul Chadda, Taeho Lee, Robyn Mahoney-Kruszka, Elizabeth G Kelley, Nathan Bernhardt, Priyanka Sandal & Janice L Robertson (2023). “A thermodynamic analysis of CLC transporter dimerization in lipid bilayers” Proc Natl Acad Sci U S A. 2023 Oct 10;120(41):e2305100120. doi: 10.1073/pnas.2305100120. Epub 2023 Oct 3. (Abstract)
Jennifer L Macdonald-Obermann & Linda J Pike (2024). “Extracellular domain mutations of the EGF receptor differentially modulate high-affinity and low-affinity responses to EGF receptor ligands” J Biol Chem. 2024 Mar;300(3):105763. doi: 10.1016/j.jbc.2024.105763. Epub 2024 Feb 16. (Abstract)
Nicole Fazio, Kacey N Mersch, Linxuan Hao, Timothy M Lohman (2023). “E. coli RecBCD Nuclease Domain Regulates Helicase Activity but not Single Stranded DNA Translocase Activity” bioRxiv. [Preprint]. 2023 Oct 17:2023.10.13.561901. doi: 10.1101/2023.10.13.561901. (Abstract)
Evelyn Ploetz, Benjamin Ambrose, Anders Barth, Richard Börner, Felix Erichson, Achillefs N Kapanidis, Harold D Kim, Marcia Levitus, Timothy M Lohman, Abhishek Mazumder, David S Rueda, Fabio D Steffen, Thorben Cordes, Steven W Magennis & Eitan Lerner (2023). “A new twist on PIFE: photoisomerisation-related fluorescence enhancement” Methods Appl Fluoresc. 2023 Oct 12;12(1):012001. doi: 10.1088/2050-6120/acfb58. (Abstract)
Chunyang Guo, Ming Cheng, Weikai Li& Michael L Gross (2023). “Precursor Reagent Hydrophobicity Affects Membrane Protein Footprinting” J Am Soc Mass Spectrom. 2023 Dec 6;34(12):2700-2710. doi: 10.1021/jasms.3c00272. Epub 2023 Nov 15. (Abstract)
Qing Cao, Zhenyu Hao, Cheng Li, Xuejie Chen, Meng Gao, Nan Jiang, Hongli Liu, Yan Shen, Haiping Yang, Shujuan Zhang, Aiying Yang, Weikai Li, Jian-Ke Tie & Guomin Shen (2023). “Molecular basis of inherited protein C deficiency results from genetic variations in the signal peptide and propeptide regions” J Thromb Haemost. 2023 Nov;21(11):3124-3137. doi: 10.1016/j.jtha.2023.06.021. Epub 2023 Jun 29. (Abstract)
Vishnu C Damalanka, Victoria Banas, Paolo De Bona, Maithri M Kashipathy, Kevin Battaile, Scott Lovell, James W Janetka (2024). “Mechanism-Based Macrocyclic Inhibitors of Serine Proteases” J Med Chem. 2024 Mar 28;67(6):4833-4854. doi: 10.1021/acs.jmedchem.3c02388. Epub 2024 Mar 13. (Abstract)
Robert Obermann, Bereket Yemane, Cassie Jarvis, Francisco M Franco, Yevhenii Kyriukha, William Nolan, Beth Gohara, Andrzej M Krezel, Scott A Wildman & James W Janetka (2024). “Small Molecule Antagonists of the DNA Repair ERCC1/XPA Protein-Protein Interaction” ChemMedChem. 2024 Apr 16;19(8):e202300648. doi: 10.1002/cmdc.202300648. Epub 2024 Mar 5. (Abstract)
Adrianus C M Boon, Traci L Bricker, Ethan J Fritch, Sarah R Leist, Kendra Gully, Ralph S Baric, Rachel L Graham, Brigid V Troan, Matthew Mahoney & James W Janetka (2024). “Efficacy of Host Cell Serine Protease Inhibitor MM3122 against SARS-CoV-2 for Treatment and Prevention of COVID-19” bioRxiv. [Preprint]. 2024 Feb 12:2024.02.09.579701. doi: 10.1101/2024.02.09.579701.. (Abstract)
Amarendar Reddy Maddirala, Kevin Tamadonfar, Jerome S Pinkner, Denise Sanick, Scott J Hultgren & James W Janetka (2024). “Discovery of Orally Bioavailable FmlH Lectin Antagonists as Treatment for Urinary Tract Infections” J Med Chem. 2024 Mar 14;67(5):3668-3678. doi: 10.1021/acs.jmedchem.3c02128. Epub 2024 Feb 3. (Abstract)
Alpha Raj Mekapogu, Zhihong Xu, Srinivasa Pothula, Chamini Perera, Tony Pang, S M Zahid Hosen, Vishnu Damalanka, James Janetka, David Goldstein, Romano Pirola, Jeremy Wilson & Minoti Apte (2023). “HGF/c-Met pathway inhibition combined with chemotherapy increases cytotoxic T-cell infiltration and inhibits pancreatic tumour growth and metastasis” Cancer Lett. 2023 Aug 1:568:216286. doi: 10.1016/j.canlet.2023.216286. Epub 2023 Jun 22. (Abstract)
Denis Belitškin, Pauliina Munne, Shishir M Pant, Johanna M Anttila, Ilida Suleymanova, Kati Belitškina, Daniel Kirchhofer, James Janetka, Taivo Käsper, Sami Jalil, Jeroen Pouwels, Topi A Tervonen & Juha Klefström (2024). “Hepsin promotes breast tumor growth signaling via the TGFβ-EGFR axis” Mol Oncol. 2024 Mar;18(3):547-561. doi: 10.1002/1878-0261.13545. Epub 2023 Nov 13. (Abstract)
Vivian Truong Jones, Ramona Graves-Deal, Zheng Cao, Galina Bogatcheva, Marisol A Ramirez, Sarah J Harmych, James N Higginbotham, Vineeta Sharma, Vishnu C Damalanka, Claudia C Wahoski, Neeraj Joshi, Maria Johnson Irudayam, Joseph T Roland, Gregory D Ayers, Qi Liu, Robert J Coffey, James W Janetka & Bhuminder Singh (2024). “Inhibition of autocrine HGF maturation overcomes cetuximab resistance in colorectal cancer” Cell Mol Life Sci. 2024 Jan 12;81(1):28. doi: 10.1007/s00018-023-05071-5. (Abstract)
Whitney R Grither, Breanna Baker, Vasilios A Morikis, Ma Xenia G Ilagan, Katherine C Fuh, & Gregory D Longmore (2024). “ROR2/Wnt5a Signaling Regulates Directional Cell Migration and Early Tumor Cell Invasion in Ovarian Cancer” Mol Cancer Res. 2024 May 2;22(5):495-507. doi: 10.1158/1541-7786.MCR-23-0616. (Abstract)
Sofia V Salvatore, Ma Xenia G Ilagan, Hongjin Shu, Peter M Lambert, Ann Benz, Mingxing Qian, Douglas F Covey, Charles F Zorumski, & Steven Mennerick (2024). “Neuroactive steroid effects on autophagy in a human embryonic kidney 293 (HEK) cell model” Sci Rep. 2024 Jan 10;14(1):1042. doi: 10.1038/s41598-024-51582-x. (Abstract)
Ankit Garg, Silvia Jansen, Rui Zhang, Kory J Lavine, & Michael J Greenberg (2024). “Dilated cardiomyopathy-associated skeletal muscle actin (ACTA1) mutation R256H disrupts actin structure and function and causes cardiomyocyte hypocontractility” bioRxiv [Preprint]. 2024 Mar 12:2024.03.10.583979. doi: 10.1101/2024.03.10.583979 (Abstract)
Ankit Garg, Kory J Lavine, & Michael J Greenberg (2024). “Assessing Cardiac Contractility From Single Molecules to Whole Hearts” JACC Basic Transl Sci. 2023 Oct 11;9(3):414-439. doi: 10.1016/j.jacbts.2023.07.013. eCollection 2024 Mar. (Abstract)
Gretchen A Meyer, Jeremie L A Ferey, James A Sanford, Liam S Fitzgerald, Akiva E Greenberg, Kristoffer Svensson, Michael J Greenberg, & Simon Schenk (2024). “Insights into post-translational regulation of skeletal muscle contractile function by the acetyltransferases, p300 and CBP” bioRxiv [Preprint]. 2024 Feb 29:2024.02.27.582179. doi: 10.1101/2024.02.27.582179. (Abstract)
Shahnaz Ghahremani, Aditya Kanwal, Anthony Pettinato, Feria Ladha, Nicholas Legere, Ketan Thakar, Yanfen Zhu, Harianto Tjong, Andrea Wilderman, W Tom Stump, Lina Greenberg, Michael J Greenberg, Justin Cotney, Chia-Lin Wei, & J Travis Hinson (2024). “CRISPR Activation Reverses Haploinsufficiency and Functional Deficits Caused by TTN Truncation Variants” Circulation. 2024 Apr 16;149(16):1285-1297. doi: 10.1161/CIRCULATIONAHA.123.063972. Epub 2024 Jan 18. (Abstract)
Brent Scott & Michael J Greenberg (2023). “Multiscale biophysical models of cardiomyopathies reveal complexities challenging existing dogmas” Biophys J. 2023 Dec 19;122(24):4632-4634. doi: 10.1016/j.bpj.2023.11.014. Epub 2023 Nov 25. (Abstract)
Mor Varon, Daniel Dovrat, Jonathan Heuzé, Ioannis Tsirkas, Saurabh P Singh, Philippe Pasero, Roberto Galletto, & Amir Aharoni (2024). “Rrm3 and Pif1 division of labor during replication through leading and lagging strand G-quadruplex” Nucleic Acids Res. 2024 Feb 28;52(4):1753-1762. doi: 10.1093/nar/gkad1205. (Abstract)
Ankita Chadda, Alexander G Kozlov, Binh Nguyen, Timothy M Lohman, & Eric A Galburt (2024). “Mycobacterium tuberculosis Ku Stimulates Multi-round DNA Unwinding by UvrD1 Monomers” J Mol Biol. 2024 Jan 15;436(2):168367. doi: 10.1016/j.jmb.2023.168367. Epub 2023 Nov 14. (Abstract)
Drake Jensen, Ana Ruiz Manzano, Maxwell Rector, Eric J Tomko, M Thomas Record, & Eric A Galburt (2023). “High-throughput, fluorescent-aptamer-based measurements of steady-state transcription rates for the Mycobacterium tuberculosis RNA polymerase” J Cell Biol. 2024 Jan 1;223(1):e202312031. doi: 10.1083/jcb.202312031. Epub 2023 Dec 12. (Abstract)
John A Cooper (2024). “Capping protein regulators of actin assembly in budding yeast” J Cell Biol. 2024 Jan 1;223(1):e202312031. doi: 10.1083/jcb.202312031. Epub 2023 Dec 12. (Abstract)
Olivia L Mooren, Melissa D Stuchell-Brereton, Patrick McConnell, Chenbo Yan, Emily M Wilkerson, Dennis Goldfarb, John A Cooper, David Sept, & Andrea Soranno (2023). “Biophysical Mechanism of Allosteric Regulation of Actin Capping Protein” J Mol Biol. 2023 Dec 15;435(24):168342. doi: 10.1016/j.jmb.2023.168342. Epub 2023 Nov 2. (Abstract)
Alpha Raj Mekapogu, Zhihong Xu, Srinivasa Pothula, Chamini Perera, Tony Pang, S M Zahid Hosen, Vishnu Damalanka, James Janetka, David Goldstein, Romano Pirola, Jeremy Wilson & Minoti Apte (2023). “HGF/c-Met pathway inhibition combined with chemotherapy increases cytotoxic T-cell infiltration and inhibits pancreatic tumour growth and metastasis” Cancer Lett. 2023 Aug 1:568:216286. doi: 10.1016/j.canlet.2023.216286. Epub 2023 Jun 22. (Abstract)
Denis Belitškin, Pauliina Munne, Shishir M Pant, Johanna M Anttila, Ilida Suleymanova, Kati Belitškina, Daniel Kirchhofer, James Janetka, Taivo Käsper, Sami Jalil, Jeroen Pouwels, Topi A Tervonen & Juha Klefström (2024). “Hepsin promotes breast tumor growth signaling via the TGFβ-EGFR axis” Mol Oncol. 2024 Mar;18(3):547-561. doi: 10.1002/1878-0261.13545. Epub 2023 Nov 13. (Abstract)
Vivian Truong Jones, Ramona Graves-Deal, Zheng Cao, Galina Bogatcheva, Marisol A Ramirez, Sarah J Harmych, James N Higginbotham, Vineeta Sharma, Vishnu C Damalanka, Claudia C Wahoski, Neeraj Joshi, Maria Johnson Irudayam, Joseph T Roland, Gregory D Ayers, Qi Liu, Robert J Coffey, James W Janetka & Bhuminder Singh (2024). “Inhibition of autocrine HGF maturation overcomes cetuximab resistance in colorectal cancer” Cell Mol Life Sci. 2024 Jan 12;81(1):28. doi: 10.1007/s00018-023-05071-5. (Abstract)
Robert Obermann, Bereket Yemane, Cassie Jarvis, Francisco M Franco, Yevhenii Kyriukha, William Nolan, Beth Gohara, Andrzej M Krezel, Scott A Wildman & James W Janetka (2024). “Small Molecule Antagonists of the DNA Repair ERCC1/XPA Protein-Protein Interaction” ChemMedChem. 2024 Feb 1:e202300648. doi: 10.1002/cmdc.202300648. Online ahead of print. (Abstract)
Amarendar Reddy Maddirala, Kevin Tamadonfar, Jerome S Pinkner, Denise Sanick, Scott J Hultgren & James W Janetka (2024). “Discovery of Orally Bioavailable FmlH Lectin Antagonists as Treatment for Urinary Tract Infections” J Med Chem. 2024 Mar 14;67(5):3668-3678. doi: 10.1021/acs.jmedchem.3c02128. Epub 2024 Feb 3. (Abstract)
Vishnu C Damalanka, Victoria Banas, Paolo De Bona, Maithri M Kashipathy, Kevin Battaile, Scott Lovell & James W Janetka (2024). “Mechanism-Based Macrocyclic Inhibitors of Serine Proteases” J Med Chem2024 Mar 28;67(6):4833-4854. doi: 10.1021/acs.jmedchem.3c02388. Epub 2024 Mar 13. (Abstract)
Adrianus C. M. Boon, Traci L. Bricker, Ethan J. Fritch, Sarah R. Leist, Kendra Gully, Ralph S. Baric, Rachel L. Graham, Brigid V. Troan, Matthew Mahoney & James W. Janetka (2024). “Efficacy of host cell serine protease inhibitor MM3122 against SARS-CoV-2 for treatment and prevention of COVID-19.” J Virol. 2024 Apr;9. doi:10.1128/jvi.01903-23 (Abstract)