High resolution crystal structure of rat long chain hydroxy acid oxidase in complex with the inhibitor 4-carboxy-5-[(4-chlorophenyl)sulfanyl]-1, 2, 3-thiadiazole. Implications for inhibitor specificity and drug design.

(May 9th, 2012)

Chen Z.W., Vignaud C., Jaafar A., Levy B., Gueritte F., Guenard D., Lederer F., & Mathews F.S. (2012). “High resolution crystal structure of rat long chain hydroxy acid oxidase in complex with the inhibitor 4-carboxy-5-[(4-chlorophenyl)sulfanyl]-1, 2, 3-thiadiazole. Implications for inhibitor specificity and drug design.” Biochimie. 2012 May;94(5):1172-9. doi: 10.1016/j.biochi.2012.02.003. Epub 2012 Feb 9. (Abstract)