Spotlight on Research – Burgers Lab

The Burgers Lab studies DNA replication and DNA damage response in eukaryotic cells. Using yeast as a model organism, the lab integrates the biochemical analysis of DNA-protein interactions in purified model systems with the genetic analysis of targeted yeast mutants. Specific areas of interest are lagging strand DNA replication and Okazaki fragment maturation, damage induced mutagenesis, and DNA damage cell cycle checkpoints.

DNA replication fork and Okazaki fragment maturation