Maxene Ilagan

Maxene Ilagan
Assistant Professor

Biochemistry and Molecular Biophysics

Lab Website
Publications (PubMed / NIH)

Office: 2603 Cancer Research Building
Phone: 314-362-4445

Select Publications

Heitmeier M.R., Hresko R.C., Edwards R.L., Prinsen M.J., Ilagan M.X.G., Odom John A.R, & Hruz P.W. (2019). “Identification of druggable small molecule antagonists of the Plasmodium falciparum hexose transporter PfHT and assessment of ligand access to the glucose permeation pathway via FLAG-mediated protein engineering.” PLoS One. 2019 May 9;14(5):e0216457. doi: 10.1371/journal.pone.0216457. eCollection 2019. (Abstract)

Liu G., Nash P.J., Johnson B., Pietzsch C., Ilagan M.X., Bukreyev A., Basler C.F., Bowlin T.L., Moir D.T., Leung D.W., & Amarasinghe G.K. (2017). “A Sensitive in Vitro High-Throughput Screen To Identify Pan-filoviral Replication Inhibitors Targeting the VP35-NP Interface.” ACS Infect Dis. 2017 Mar 10;3(3):190-198. doi: 10.1021/acsinfecdis.6b00209. Epub 2017 Feb 9. (Abstract)

Kraft T.E., Heitmeier M.R., Putanko M., Edwards R.L., Ilagan M.X., Payne M.A., Autry J.M., Thomas D.D., Odom A.R., and Hruz P.W. (2016) “A Novel Fluorescence Resonance Energy Transfer-Based Screen in High-Throughput Format To Identify Inhibitors of Malarial and Human Glucose Transporters.” Antimicrob Agents Chemother. 2016 Nov 21;60(12):7407-7414. Print 2016 Dec. (Abstract)

Thomas J.J., Abed M., Heuberger J., Novak R., Zohar Y., Beltran Lopez A.P., Trausch-Azar J.S., Ilagan M.X., Benhamou D., Dittmar G., Kopan R., Birchmeier W., Schwartz A.L., and Orian A. (2016) “RNF4-Dependent Oncogene Activation by Protein Stabilization.” Cell Rep. 2016 Sep 20;16(12):3388-3400. doi: 10.1016/j.celrep.2016.08.024. (Abstract)

Ilagan M.X. and Kopan R. (2014) “Monitoring Notch activation in cultured mammalian cells: luciferase complementation imaging assays.” Methods Mol Biol. 2014;1187:155-68. doi: 10.1007/978-1-4939-1139-4_12. (Abstract)

Yang K.S., Ilagan M.X., Pinica-Worms D. and Pike L.J. (2009) “Luciferase fragment complementation imaging of conformational changes in the epidermal growth factor receptor.” J Biol Chem. 2009 Mar 20;284(12):7474-82. doi: 10.1074/jbc.M808041200. Epub 2009 Jan 26. (Abstract)