Alexander Kozlov

Alexander Kozlov
Research Instructor

Biochemistry and Molecular Biophysics

Lab Website

Room: 2803 North Building
Phone: 314-362-4394

Select Publications

Alexander G. Kozlov & Timothy M. Lohman (2021). “Probing E. coli SSB Protein-DNA topology by reversing DNA backbone polarity” Biophys J. 2021 Apr 20;120(8):1522-1533. doi: 10.1016/j.bpj.2021.02.025. Epub 2021 Feb 23. (Abstract)

Min Kyung Shinn, Alexander G. Kozlov, & Timothy M. Lohman (2021). “Allosteric effects of SSB C-terminal tail on assembly of E. coli RecOR proteins” Nucleic Acids Res. 2021 Feb 26;49(4):1987-2004. doi: 10.1093/nar/gkaa1291. (Abstract)

Katarzyna Dubiel, Camille Henry, Lisanne M. Spenkelink, Alexander G. Kozlov, Elizabeth A. Wood, Slobodan Jergic, Nicholas E. Dixon, Antoine M. van Oijen, Michael M. Cox, Timothy M. Lohman, Steven J. Sandler, & James L. Keck (2020). “Development of a Single-Stranded DNA-binding Protein Fluorescent Fusion Toolbox” Nucleic Acids Res. 2020 Jun 19;48(11):6053-6067. doi: 10.1093/nar/gkaa320. (Abstract)

Patrick McConnell, Marlene Mekel, Alex G. Kozlov, Olivia L. Mooren, Timothy M. Lohman, & John A. Cooper (2020). “Comparative Analysis of CPI-Motif Regulation of Biochemical Functions of Actin Capping Protein” Biochemistry. 2020 Mar 24;59(11):1202-1215. doi: 10.1021/acs.biochem.0c00092. Epub 2020 Mar 10. (Abstract)

Alexander G. Kozlov, Min Kyung Shinn, & Timothy M. Lohman (2019). “Regulation of Nearest-neighbor cooperative binding of E. coli SSB protein to DNA” Biophysical Journal. 28 October 2019. (Abstract)

Ordabayev Y.A., Nguyen B., Kozlov A.G., Jia H., & Lohman T.M. (2019). “UvrD helicase activation by MutL involves rotation of its 2B subdomain.” Proc Natl Acad Sci U S A. 2019 Jul 30. pii: 201905513. doi: 10.1073/pnas.1905513116. [Epub ahead of print] (Abstract)

Shinn M.K., Kozlov A.G., Nguyen B., Bujalowski W.M., & Lohman T.M. (2019). “Are the intrinsically disordered linkers involved in SSB binding to accessory proteins?” Nucleic Acids Res. 2019 Jul 22. pii: gkz606. doi: 10.1093/nar/gkz606. [Epub ahead of print] (Abstract)

Nguyen B., Ciuba M.A., Kozlov A.G., Levitus M., & Lohman T.M. (2019). “Protein Environment and DNA Orientation Affect Protein-Induced Cy3 Fluorescence Enhancement.” Biophys J. 2019 Jun 7. pii: S0006-3495(19)30448-5. doi: 10.1016/j.bpj.2019.05.026. [Epub ahead of print] (Abstract)

Min Kyung Shinn, Alexander G. Kozlov, & Timothy M. Lohman. (2019). “Binding Specificity of E. coli SSB C-Terminal Tails to SIPs” Biophysical Journal. Volume 116, Issue 3, Supplement 1, 15 February 2019, Page 77a. (Abstract)

Katarzyna Dubiel, Angela R. Myers, Alexander G. Kozlov, Olivia Yang, Jichuan Zhang, Taekjip Ha, Timothy M. Lohman, & James L. Keck (2019). “Structural Mechanisms of Cooperative DNA Binding by Bacterial Single-Stranded DNA-Binding Proteins” J Mol Biol. 2019 Jan 18;431(2):178-195. doi: 10.1016/j.jmb.2018.11.019. Epub 2018 Nov 22. (Abstract)

Johnson B., McConnell P., Kozlov A.G., Mekel M., Lohman T.M., Gross M.L., Amarasinghe G.K., & Cooper J.A. (2018). “Allosteric Coupling of CARMIL and V-1 Binding to Capping Protein Revealed by Hydrogen-Deuterium Exchange.” Cell Rep. 2018 May 29;23(9):2795-2804. doi: 10.1016/j.celrep.2018.04.096. (Abstract)

Min Kyung Shinn, Alexander G. Kozlov, & Timothy M. Lohman (2018). “Allosteric Effect of E. coli SSB C-Terminal Tails on RecOR Binding to DNA” Biophysical Journal, Volume 114, Issue 3, Supplement 1, 2 February 2018, Page 441a (Abstract)

Kozlov A.G., Shinn M.K., Weiland E.A., & Lohman T.M. (2017). “Glutamate promotes SSB protein-protein Interactions via intrinsically disordered regions.” J Mol Biol. 2017 Sep 1;429(18):2790-2801. doi: 10.1016/j.jmb.2017.07.021. Epub 2017 Aug 3. (Abstract)

Waldman V.M., Weiland E., Kozlov A.G., & Lohman T.M. (2016). “Is a fully wrapped SSB-DNA complex essential for Escherichia coli survival?” Nucleic Acids Res. 2016 May 19;44(9):4317-29. doi: 10.1093/nar/gkw262. Epub 2016 Apr 15. (Abstract)

Sokoloski J.E., Kozlov A.G., Galletto R., & Lohman T.M. (2016). “Chemo-mechanical pushing of proteins along single-stranded DNA.” Proc Natl Acad Sci U S A. 2016 May 31;113(22):6194-9. doi: 10.1073/pnas.1602878113. Epub 2016 May 16. (Abstract)