Alexander Kozlov

Alexander Kozlov
Research Instructor

Biochemistry and Molecular Biophysics

Lab Website

Room: 2803 North Building
Phone: 314-362-4394

Select Publications

Nguyen B., Ciuba M.A., Kozlov A.G., Levitus M., & Lohman T.M. (2019). “Protein Environment and DNA Orientation Affect Protein-Induced Cy3 Fluorescence Enhancement.” Biophys J. 2019 Jun 7. pii: S0006-3495(19)30448-5. doi: 10.1016/j.bpj.2019.05.026. [Epub ahead of print] (Abstract)

Min Kyung Shinn, Alexander G. Kozlov, & Timothy M. Lohman. (2019). “Binding Specificity of E. coli SSB C-Terminal Tails to SIPs” Biophysical Journal. Volume 116, Issue 3, Supplement 1, 15 February 2019, Page 77a. (Abstract)

Dubiel K., Myers A.R., Kozlov A.G., Yang O., Zhang J., Ha T., Lohman T.M., & Keck J.L. (2018). “Structural Mechanisms of Cooperative DNA Binding by Bacterial Single-Stranded DNA-Binding Proteins.” J Mol Biol. 2018 Nov 22. pii: S0022-2836(18)31046-5. doi: 10.1016/j.jmb.2018.11.019. [Epub ahead of print] (Abstract)

Johnson B., McConnell P., Kozlov A.G., Mekel M., Lohman T.M., Gross M.L., Amarasinghe G.K., & Cooper J.A. (2018). “Allosteric Coupling of CARMIL and V-1 Binding to Capping Protein Revealed by Hydrogen-Deuterium Exchange.” Cell Rep. 2018 May 29;23(9):2795-2804. doi: 10.1016/j.celrep.2018.04.096. (Abstract)

Min Kyung Shinn, Alexander G. Kozlov, & Timothy M. Lohman (2018). “Allosteric Effect of E. coli SSB C-Terminal Tails on RecOR Binding to DNA” Biophysical Journal, Volume 114, Issue 3, Supplement 1, 2 February 2018, Page 441a (Abstract)

Kozlov A.G., Shinn M.K., Weiland E.A., & Lohman T.M. (2017). “Glutamate promotes SSB protein-protein Interactions via intrinsically disordered regions.” J Mol Biol. 2017 Sep 1;429(18):2790-2801. doi: 10.1016/j.jmb.2017.07.021. Epub 2017 Aug 3. (Abstract)

Waldman V.M., Weiland E., Kozlov A.G., & Lohman T.M. (2016). “Is a fully wrapped SSB-DNA complex essential for Escherichia coli survival?” Nucleic Acids Res. 2016 May 19;44(9):4317-29. doi: 10.1093/nar/gkw262. Epub 2016 Apr 15. (Abstract)

Sokoloski J.E., Kozlov A.G., Galletto R., & Lohman T.M. (2016). “Chemo-mechanical pushing of proteins along single-stranded DNA.” Proc Natl Acad Sci U S A. 2016 May 31;113(22):6194-9. doi: 10.1073/pnas.1602878113. Epub 2016 May 16. (Abstract)

Suksombat S., Khafizov R., Kozlov A.G., Lohman T.M., & Chemla Y.R. (2015). “Structural dynamics of E. coli single-stranded DNA binding protein reveal DNA wrapping and unwrapping pathways.” Elife. 2015 Aug 25;4. doi: 10.7554/eLife.08193. (Abstract)

Kozlov A.G., Weiland E., Mittal A., Waldman V., Antony E., Fazio N., Pappu R.V., & Lohman T.M. (2015). “Intrinsically disordered C-terminal tails of E. coli single-stranded DNA binding protein regulate cooperative binding to single-stranded DNA.” J Mol Biol. 2015 Feb 27;427(4):763-74. doi: 10.1016/j.jmb.2014.12.020. Epub 2015 Jan 3. (Abstract)

Lee K.S., Marciel A.B., Kozlov A.G., Schroeder C.M., Lohman T.M., & Ha T. (2014). “Ultrafast redistribution of E. coli SSB along long single-stranded DNA via intersegment transfer.” J Mol Biol. 2014 Jun 26;426(13):2413-21. doi: 10.1016/j.jmb.2014.04.023. Epub 2014 May 2. (Abstract)

Antony E., Weiland E., Yuan Q., Manhart C.M., Nguyen B., Kozlov A.G., McHenry C.S., & Lohman T.M. (2013). “Multiple C-terminal tails within a single E. coli SSB homotetramer coordinate DNA replication and repair.” J Mol Biol. 2013 Nov 29;425(23):4802-19. doi: 10.1016/j.jmb.2013.08.021. Epub 2013 Sep 7. (Abstract)

Kozlov A.G., Galletto R., & Lohman T.M. (2012). “SSB-DNA binding monitored by fluorescence intensity and anisotropy.” Methods Mol Biol. 2012;922:55-83. doi: 10.1007/978-1-62703-032-8_4. (Abstract)

Kozlov A.G. & Lohman T.M. (2012). “SSB binding to ssDNA using isothermal titration calorimetry.” Methods Mol Biol. 2012;922:37-54. doi: 10.1007/978-1-62703-032-8_3. (Abstract)

Antony E., Kozlov A.G., Nguyen B., & Lohman T.M. (2012). “Plasmodium falciparum SSB tetramer binds single-stranded DNA only in a fully wrapped mode.” J Mol Biol. 2012 Jul 20;420(4-5):284-95. doi: 10.1016/j.jmb.2012.04.022. Epub 2012 Apr 26. (Abstract)