Natalie M. Niemi, Ph.D.

Natalie Niemi
Assistant Professor

Biochemistry and Molecular Biophysics

Lab Website
Publications (PubMed / NIH)

Office: 2813 North Building



The Niemi Lab investigates how mitochondria are built, regulated, and maintained across physiological contexts. We blend biochemistry, systems biology, and physiology to understand mechanisms of mitochondrial regulation and how they influence metabolism and organellar function. Using insights gained from our molecular studies, we aim to understand how mitochondrial dysfunction contributes to mammalian pathophysiology, with the long-term goal of translating our discoveries into new therapeutic options to restore mitochondrial function in human disease.

Mechanisms of mitochondrial biogenesis, regulation, and turnover.

Select Publications

Jesse G. Meyer, Natalie M. Niemi, David J. Pagliarini, & Joshua J. Coon (2020). “Quantitative shotgun proteome analysis by direct infusion” Nat Methods. 2020 Dec;17(12):1222-1228. doi: 10.1038/s41592-020-00999-z. Epub 2020 Nov 23. (Abstract)

Jason D Fernandes, Sarvenaz Sarabipour, Christopher T Smith, Natalie M Niemi, Nafisa M Jadavji, Ariangela J Kozik, Alex S Holehouse, Vikas Pejaver, Orsolya Symmons, Alexandre W Bisson Filho, & Amanda Haage (2020). “A survey-based analysis of the academic job market” Elife. 2020 Jun 12;9:e54097. doi: 10.7554/eLife.54097. Online ahead of print. (Abstract)