Recent Publications

Publications by faculty, post-doctoral associates, students, and staff of Biochemistry and Molecular Biophysics.

More can be found in the Archives.

  • Kunkel T.A. and Burgers P.M.
    Arranging eukaryotic nuclear DNA polymerases for replication: Specific interactions with accessory proteins arrange Pols α, δ, and ϵ in the replisome for leading-strand and lagging-strand DNA replication.
    Bioessays. 39(8). (2017) (Abstract)

  • Albert B.J., Niu A., Ramani R., Marshall G.R., Wender P.A., Williams R.M., Ratner L., Barnes A.B., and Kyei G.B.
    Combinations of isoform-targeted histone deacetylase inhibitors and bryostatin analogues display remarkable potency to activate latent HIV without global T-cell activation.
    Sci Rep. 7(1):7456. (2017) (Abstract)

  • Kozlov A.G., Shinn M.K., Weiland E.A., and Lohman T.M.
    Glutamate promotes SSB protein-protein Interactions via intrinsically disordered regions.
    J Mol Biol. pii: S0022-2836(17)30371-6. (2017) (Abstract)

  • McCune B.T., Tang W., Lu J., Eaglesham J.B., Thorne L., Mayer A.E., Condiff E., Nice T.J., Goodfellow I., Krezel A.M., and Virgin H.W.
    Noroviruses Co-opt the Function of Host Proteins VAPA and VAPB for Replication via a Phenylalanine-Phenylalanine-Acidic-Tract-Motif Mimic in Nonstructural Viral Protein NS1/2.
    MBio. 8(4) (2017) (Abstract)

  • Rebekah H. Griesenauer and Michael S.Kinch
    2016 in review: FDA approvals of new molecular entities
    Drug Discovery Today. S1359-6446(17)30129-0. (2017) (Abstract)

  • Franziska Zosel, Dominik Haenni, Andrea Soranno, Daniel Nettels, and Benjamin Schuler
    Combining short- and long-range fluorescence reporters with simulations to explore the intramolecular dynamics of an intrinsically disordered protein
    The Journal of Chemical Physics, Volume 147, Issue 15 (2017). (Abstract)

  • Stark B.C., Lanier M.H., and Cooper J.A.
    CARMIL family proteins as multidomain regulators of actin-based motility.
    Mol Biol Cell. 28(13):1713-1723 (2017) (Abstract)

  • Stewart-Hutchinson P.J., Szasz T.P., Jaeger E.R., Onken M.D., Cooper J.A., and Morley S.C.
    Technical Advance: New in vitro method for assaying the migration of primary B cells using an endothelial monolayer as substrate.
    J Leukoc Biol. (2017) (Abstract)

  • Caitlin N. Spaulding, Roger D. Klein, Ségolène Ruer, Andrew L. Kau, Henry L. Schreiber, Zachary T. Cusumano, Karen W. Dodson, Jerome S. Pinkner, Daved H. Fremont, James W. Janetka, Han Remaut, Jeffrey I. Gordon, & Scott J. Hultgren
    Selective depletion of uropathogenic E. coli from the gut by a FimH antagonist
    Nature (2017) (Abstract)

  • Frieden C., Wang H., and Ho C.M.W.
    A mechanism for lipid binding to apoE and the role of intrinsically disordered regions coupled to domain-domain interactions.
    Proc Natl Acad Sci U S A. 114(24):6292-6297. (2017) (Abstract)

  • Benjamin Y. Owusu, Shantasia Thomas, Phanindra Venukadasula, Zhenfu Han, James W. Janetka, Robert A. Galemmo Jr and Lidija Klampfer
    Targeting the tumor-promoting microenvironment in MET-amplified NSCLC cells with a novel inhibitor of pro-HGF activation
    Oncotarget (2017) (Abstract)

  • Kinch M.S. and Woodard P.K.
    Analysis of FDA-approved imaging agents.
    Drug Discov Today. (2017) (Abstract)

  • Mydock-McGrane L.K., Hannan T.J., and Janetka J.W.
    Rational Design Strategies for FimH Antagonists: New Drugs on the Horizon for Urinary Tract Infection and Crohn’s Disease.
    Expert Opin Drug Discov. (2017) (Abstract)

  • Wang H., Shu Q., Frieden C., and Gross M.L.
    Deamidation slows Curli Amyloid-Protein Aggregation.
    Biochemistry. (2017) (Abstract)

  • Benjamin Yaw Owusu, Robert Galemmo, James Janetka, and Lidija Klampfer
    Hepatocyte Growth Factor, a Key Tumor-Promoting Factor in the Tumor Microenvironment
    Cancers 2017, 9(4), 35 (2017) (Abstract)

  • Melissa M Budelier, Wayland WL Cheng, Lucie Bergdoll, Zi-Wei Chen, James W Janetka, Jeff Abramson, Kathiresan Krishnan, Laurel Mydock-McGrane, Douglas F Covey, Julian P Whitelegge, and Alex S Evers
    Photoaffinity labeling with cholesterol analogues precisely maps a cholesterol-binding site in voltage-dependent anion channel-1
    Journal of Biological Chemistry (2017) (Abstract)

  • Sun X., Laroche G., Wang X., Ågren H., Bowman G.R., Giguère P.M., and Tu Y.
    Propagation of the Allosteric Modulation Induced by Sodium in the δ-Opioid Receptor.
    Chemistry 23(19):4615-4624 (2017) (Abstract)

  • Tianyang Liu, Anbang Dai, Yong Cao, Rui Zhang, Meng-Qiu Dong, and Hong-Wei Wang
    Structural insights of WHAMM’s interaction with microtubules by cryo-EM
    Journal of Molecular Biology 429:1352–1363 (2017) (Abstract)

  • Sukrit Singh and Gregory R. Bowman
    Quantifying allosteric communication via both concerted structural changes and conformational disorder with CARDS
    J. Chem. Theory Comput. (2017) (Abstract)

  • Burgers P.M. and Kunkel T.A.
    Eukaryotic DNA Replication Fork.
    Annu Rev Biochem. 86:417-438 (2017) (Abstract)

  • Ballante F., Reddy D.R., Zhou N.J., and Marshall G.R.
    Structural insights of SmKDAC8 inhibitors: Targeting Schistosoma epigenetics through a combined structure-based 3D QSAR, in vitro and synthesis strategy.
    Bioorg Med Chem. (2017) (Abstract)

  • Vasilios Kalas, Jerome S. Pinkner, Thomas J. Hannan, Michael E. Hibbing, Karen W. Dodson, Alex S. Holehouse, Hao Zhang, Niraj H. Tolia, Michael L. Gross, Rohit V. Pappu, James Janetka and Scott J. Hultgren
    Evolutionary fine-tuning of conformational ensembles in FimH during host-pathogen interactions
    Science Advances Vol. 3, no. 2 (2017) (Abstract)

  • Galburt E.A. and Tomko E.J.
    Conformational selection and induced fit as a useful framework for molecular motor mechanisms.
    Biophys Chem. 223:11-16 (2017) (Abstract)

  • Chang Y.K., Srivastava Y., Hu C., Joyce A., Yang X., Zuo Z., Havranek J.J., Stormo G.D., and Jauch R.
    Quantitative profiling of selective Sox/POU pairing on hundreds of sequences in parallel by Coop-seq.
    Nucleic Acids Res. (2017) (Abstract)

  • Santiago-Tirado F.H., Onken M.D., Cooper J.A., Klein R.S., and Doering T.L.
    Trojan Horse Transit Contributes to Blood-Brain Barrier Crossing of a Eukaryotic Pathogen.
    MBio. (2017) (Abstract)

More can be found in the Archives.