Rui Zhang

Assistant Professor

Biochemistry and Molecular Biophysics

Lab Website
Publications (PubMed / NIH)

Office: 253 McDonnell Sciences Building
Phone: 314-273-1663
E-mail: zhangrui@wustl.edu

 

Select Publications

Venecia Valdez, Meisheng Ma, Bernardo Gouveia, Rui Zhang & Sabine Petry (2024). “HURP facilitates spindle assembly by stabilizing microtubules and working synergistically with TPX2” bioRxiv. [Preprint]. 2023 Dec 18:2023.12.18.571906. doi: 10.1101/2023.12.18.571906. (Abstract)

Kiarash Jamali, Lukas Käll, Rui Zhang, Alan Brown, Dari Kimanius & Sjors H W Scheres (2024). “Automated model building and protein identification in cryo-EM maps” Nature. 2024 Apr;628(8007):450-457. doi: 10.1038/s41586-024-07215-4. Epub 2024 Feb 26. (Abstract)

Ankit Garg, Silvia Jansen, Rui Zhang, Kory J Lavine & Michael J Greenberg (2024). “Dilated cardiomyopathy-associated skeletal muscle actin (ACTA1) mutation R256H disrupts actin structure and function and causes cardiomyocyte hypocontractility” bioRxiv. [Preprint]. 2024 Mar 12:2024.03.10.583979. doi: 10.1101/2024.03.10.583979. (Abstract)

Steven L Brody, Jiehong Pan, Tao Huang, Jian Xu, Huihui Xu, Jeffrey Koenitizer, Steven K Brennan, Rashmi Nanjundappa, Thomas G Saba, Andrew Berical, Finn J Hawkins, Xiangli Wang, Rui Zhang, Moe R Mahjoub, Amjad Horani & Susan K Dutcher (2024). “Loss of an extensive ciliary connectome induces proteostasis and cell fate switching in a severe motile ciliopathy” bioRxiv. [Preprint]. 2024 Mar 21:2024.03.20.585965. doi: 10.1101/2024.03.20.585965. (Abstract)

Jin Dai, Meisheng Ma, Qingwei Niu, Robyn J Eisert, Xiangli Wang, Poulomi Das, Karl F Lechtreck, Susan K Dutcher, Rui Zhang & Alan Brown (2024). “Mastigoneme structure reveals insights into the O-linked glycosylation code of native hydroxyproline-rich helices” Cell. 2024 Apr 11;187(8):1907-1921.e16. doi: 10.1016/j.cell.2024.03.005. Epub 2024 Mar 28. (Abstract)

Ankit Garg, Silvia Jansen, Rui Zhang, Kory J Lavine, & Michael J Greenberg (2024). “Dilated cardiomyopathy-associated skeletal muscle actin (ACTA1) mutation R256H disrupts actin structure and function and causes cardiomyocyte hypocontractility” bioRxiv [Preprint]. 2024 Mar 12:2024.03.10.583979. doi: 10.1101/2024.03.10.583979 (Abstract)

Linxuan Hao, Rui Zhang, & Timothy M. Lohman (2021). “Heterogeneity in E. coli RecBCD Helicase-DNA Binding and Base Pair Melting” J Mol Biol. 2021 Sep 3;433(18):167147. doi: 10.1016/j.jmb.2021.167147. Epub 2021 Jul 9. (Abstract)

Xiangli Wang, Yong Fu, Wandy L. Beatty, Meisheng Ma, Alan Brown, L. David Sibley, & Rui Zhang (2021). “Cryo-EM structure of cortical microtubules from human parasite Toxoplasma gondii identifies their microtubule inner proteins” Nat Commun. 2021 May 24;12(1):3065. doi: 10.1038/s41467-021-23351-1. (Abstract)

Miao Gui, Meisheng Ma, Erica Sze-Tu, Xiangli Wang, Fujiet Koh, Ellen D. Zhong, Bonnie Berger, Joseph H. Davis, Susan K. Dutcher, Rui Zhang, & Alan Brown (2020). “Structures of radial spokes and associated complexes important for ciliary motility” Nat Struct Mol Biol. 2021 Jan;28(1):29-37. doi: 10.1038/s41594-020-00530-0. Epub 2020 Dec 14. (Abstract)

Meisheng Ma, Mihaela Stoyanova, Griffin Rademacher, Susan K. Dutcher, Alan Brown, & Rui Zhang (2019). “Structure of the Decorated Ciliary Doublet Microtubule” Cell. Volume 179, Issue 4, 31 October 2019, Pages 909-922.e12. doi: 10.1016/j.cell.2019.09.030 (Abstract)

Lisa Eshun-Wilson, Rui Zhang, Didier Portran, Maxence Nachury, Daniel Toso, Thomas Lohr, Michelle Vendruscolo, Massimiliano Bonomi, James Fraser, & Eva Nogales (2019). “Effects of α-tubulin acetylation on microtubule structure and stability” bioRxiv. January 09, 2019. doi.org/10.1101/516591. (Abstract)

Song J.G., King M.R., Zhang R., Kadzik R.S., Thawani A., & Petry S. (2018) “Mechanism of how augmin directly targets the γ-tubulin ring complex to microtubules.” J Cell Biol. 2018 Jul 2;217(7):2417-2428. doi: 10.1083/jcb.201711090. Epub 2018 Jun 6. (Abstract)

Zhang R., Alushin G.M., Brown A., & Nogales E. (2015) “Mechanistic Origin of Microtubule Dynamic Instability and Its Modulation by EB Proteins.” Cell. 2015 Aug 13;162(4):849-59. doi: 10.1016/j.cell.2015.07.012. Epub 2015 Jul 30. (Abstract)