A conservative isoleucine to leucine mutation causes major rearrangements and cold sensitivity in KlenTaq1 DNA polymerase.

(Jan 27th, 2015)

Wu E.Y., Walsh A.R., Materne E.C., Hiltner E.P., Zielinski B., Miller B.R. 3rd, Mawby L., Modeste E., Parish C.A., Barnes W.M., & Kermekchiev M.B. (2015). “A conservative isoleucine to leucine mutation causes major rearrangements and cold sensitivity in KlenTaq1 DNA polymerase.” Biochemistry. 2015 Jan 27;54(3):881-9. doi: 10.1021/bi501198f. Epub 2015 Jan 9. (Abstract)