Author: Nicholas Caito

Regulation of single-stranded DNA binding by the C termini of Escherichia coli single-stranded DNA-binding (SSB) protein.

Kozlov A.G., Cox M.M., and Lohman T.M. (2010) “Regulation of single-stranded DNA binding by the C termini of Escherichia coli single-stranded DNA-binding (SSB) protein.” J Biol Chem. 2010 May 28;285(22):17246-52. doi: 10.1074/jbc.M110.118273. Epub 2010 Apr 1. (Abstract)

E. coli SSB tetramer binds the first and second molecules of (dT)(35) with heat capacities of opposite sign.

Kozlov A.G. & Lohman T.M. (2010). “E. coli SSB tetramer binds the first and second molecules of (dT)(35) with heat capacities of opposite sign.” Biophys Chem. 2011 Nov;159(1):48-57. doi: 10.1016/j.bpc.2011.05.005. Epub 2011 May 12. (Abstract)

Binding specificity of Escherichia coli single-stranded DNA binding protein for the chi subunit of DNA pol III holoenzyme and PriA helicase.

Kozlov A.G., Jezewska M.J., Bujalowski W., and Lohman T.M. (2010) “Binding specificity of Escherichia coli single-stranded DNA binding protein for the chi subunit of DNA pol III holoenzyme and PriA helicase.” Biochemistry. 2010 May 4;49(17):3555-66. doi: 10.1021/bi100069s. (Abstract)

A joint x-ray and neutron study on amicyanin reveals the role of protein dynamics in electron transfer.

Sukumar N., Mathews F.S., Langan P., & Davidson V.L. (2010). “A joint x-ray and neutron study on amicyanin reveals the role of protein dynamics in electron transfer.” Proc Natl Acad Sci U S A. 2010 Apr 13;107(15):6817-22. doi: 10.1073/pnas.0912672107. Epub 2010 Mar 29. (Abstract)

Parallel multiplicative target screening against divergent bacterial replicases: identification of specific inhibitors with broad spectrum potential.

Dallmann, H.G., Fackelmayer, O.J., Tomer, G., Chen, J., Wiktor-Becker, A., Ferrara, T., Pope, C., Oliveira, M.T., Burgers, P.M., Kaguni, L.S. and McHenry, C.S.
Parallel multiplicative target screening against divergent bacterial replicases: identification of specific inhibitors with broad spectrum potential.
Biochemistry. 49:2551-2562 (2010). (Abstract)

Using ligand-based virtual screening to allosterically stabilize the activated state of a GPCR.

Taylor C.M., Rockweiler N.B., Liu C., Rikimaru L., Tunemalm A.K., Kisselev O.G., and Marshall G.R. (2010) “Using ligand-based virtual screening to allosterically stabilize the activated state of a GPCR.” Chem Biol Drug Des. 2010 Mar;75(3):325-32. doi: 10.1111/j.1747-0285.2009.00944.x. Epub 2010 Jan 19. (Abstract)