Author: Nicholas Caito
April 29th, 2019 – Andrea Soranno, PhD, Assistant Professor of Biochemistry and Molecular Biophysics received a new five year grant award from the National Institute on Aging for his research entitled “Conformational and functional analysis of Apolipoprotein E”.
Josh Rackers is a graduate student in Biophysics at Washington University in St. Louis. His work focuses on using the tools of applied quantum mechanics to predict the behavior and interactions of biological molecules. This work is motivated by a deeply held belief that physics holds the answers to many of biology’s most important problems. Josh obtained a bachelor’s degree in Physics and Political Science from The Ohio State University. While at Ohio State, he performed research on Positron Emission Tomography (PET) silicon-based detector design. Following graduation, Josh decided that the most immediate way to make an impact on the world was to become a teacher. He was selected for Teach For America, an organization that places top university graduates in teaching positions at poor, mostly-urban schools. He taught high school physics and chemistry in Baltimore, Maryland in what was certainly the most difficult and rewarding job of his career. He claims to have succeeded in persuading a generation of students that physics really does matter to the real world. (more…)
Recent progress on inhibitors of the type II transmembrane serine proteases, hepsin, matriptase and matriptase-2.
Damalanka V.C. & Janetka J.W. (2019). “Recent progress on inhibitors of the type II transmembrane serine proteases, hepsin, matriptase and matriptase-2.” Future Med Chem. 2019 Apr 4. doi: 10.4155/fmc-2018-0446. [Epub ahead of print] (Abstract)
Congratulations to Sukrit Singh for being selected for the 2019 MilliporeSigma Fellowship in memory of Dr. Gerty Cori
Sukrit is a graduate student in the Computational and Molecular Biophysics program. He is doing his PhD thesis work in the lab of Dr. Greg Bowman. Sukrit’s thesis is focused on understanding and exploiting allostery and dynamics in cellular signaling to develop anti-cancer therapeutics. (more…)
Michael Kinch (2019). “The End of the Beginning: Cancer, Immunity, and the Future of a Cure” ISBN-13: 978-1643130255, ISBN-10: 1643130250
Native Mass Spectrometry, Ion Mobility, Electron-Capture Dissociation, and Modeling Provide Structural Information for Gas-Phase Apolipoprotein E Oligomers.
Wang H., Eschweiler J., Cui W., Zhang H., Frieden C., Ruotolo B.T., & Gross M.L. (2019) “Native Mass Spectrometry, Ion Mobility, Electron-Capture Dissociation, and Modeling Provide Structural Information for Gas-Phase Apolipoprotein E Oligomers.” J Am Soc Mass Spectrom. 2019 Mar 18. doi: 10.1007/s13361-019-02148-z. [Epub ahead of print] (Abstract)
Tomko E.J. & Galburt E.A. (2019). “Single-molecule approach for studying RNAP II transcription initiation using magnetic tweezers.” Methods. 2019 Mar 18. pii: S1046-2023(18)30297-4. doi: 10.1016/j.ymeth.2019.03.010. [Epub ahead of print] (Abstract)
Congratulations to Min Kyung Shinn, whose poster at the 2019 Biophysical Society was recognized with a Student Research Achievement Award (SRAA). The SRAA Poster Competition is open to all BPS Student members who are presenting posters at the Annual Meeting. Students must register for this event when they submit their abstract in one of nine subject categories. The SRAA Poster Competition involved over 300 participants this year, a Society record. (more…)
Cooperative Changes in Solvent Exposure Identify Cryptic Pockets, Switches, and Allosteric Coupling.
Porter J.R., Moeder K.E., Sibbald C.A., Zimmerman M.I., Hart K.M., Greenberg M.J., & Bowman G.R. (2019). “Cooperative Changes in Solvent Exposure Identify Cryptic Pockets, Switches, and Allosteric Coupling.” Biophys J. 2019 Mar 5;116(5):818-830. doi: 10.1016/j.bpj.2018.11.3144. Epub 2019 Jan 25. (Abstract)