Author: Nicholas Caito

Congratulations to Darrell Baldwin!

On May 24, 2018, Mr. Darrell Baldwin received the Washington University School of Medicine 2018 Operations Staff Service Award.
The Operations Staff Service award is given to a staff member who has demonstrated outstanding leadership, exceptional performance in their position and superior service.
The department surprised Darrell with an award ceremony and celebration in the seminar room where Dr. David Perlmutter, Dean of the Medical School, said a few words and presented Darrell with his award.

Allosteric Coupling of CARMIL and V-1 Binding to Capping Protein Revealed by Hydrogen-Deuterium Exchange.

Johnson B., McConnell P., Kozlov A.G., Mekel M., Lohman T.M., Gross M.L., Amarasinghe G.K., & Cooper J.A. (2018). “Allosteric Coupling of CARMIL and V-1 Binding to Capping Protein Revealed by Hydrogen-Deuterium Exchange.” Cell Rep. 2018 May 29;23(9):2795-2804. doi: 10.1016/j.celrep.2018.04.096. (Abstract)

Ms. Melissa Budelier and Ms. Lucy Li were awarded the 2018 Ceil M. DeGutis Prize in Chemical Biology/Medicinal Chemistry.

On May 22nd, 2018, Ms. Melissa Budelier and Ms. Lucy Li were awarded the 2018 Ceil M. DeGutis Prize in Chemical Biology/Medicinal Chemistry.

Ms. Budelier presented her research entitled “Mapping Ligand Binding Sites in Integral Membrane Proteins”. Ms. Budelier was a graduate student in the Biochemistry, Biophysics and Structural Biology Program. Ms. Budelier was nominated by her thesis mentor Dr. Alex Evers. In Dr. Evers lab, Melissa’s work focused on developing chemical biology tools and mass spectrometric (MS) methods to sequence the transmembrane domains (TMDs) of integral membrane proteins (IMPs) and identified the sites at which sterol analogue photoaffinity labeling reagents modify these proteins. (more…)

2018 – International Potluck

On April 20, 2018, the department hosted its very first international potluck. We have many people bring in their favorite home cooked dishes from all over the world. Everything was very delicious!

Click on the following to view more photos or a slideshow of the photos taken at the event.

Small Molecule Inhibitors of Metabolic Enzymes Repurposed as a New Class of Anthelmintics.

Tyagi R., Maddirala A.R., Elfawal M., Fischer C., Bulman C.A., Rosa B.A., Gao X., Chugani R., Zhou M., Helander J., Brindley P.J., Tseng C.C., Greig I.R., Sakanari J., Wildman S.A., Aroian R., Janetka J.W., & Mitreva M. (2018). “Small Molecule Inhibitors of Metabolic Enzymes Repurposed as a New Class of Anthelmintics.” ACS Infect Dis. 2018 May 14. doi: 10.1021/acsinfecdis.8b00090. (Abstract)

Atypical Cadherin Dachsous1b Interacts with Ttc28 and Aurora B to Control Microtubule Dynamics in Embryonic Cleavages.

Chen J., Castelvecchi G.D., Li-Villarreal N., Raught B., Krezel A.M., McNeill H., & Solnica-Krezel L. (2018). “Atypical Cadherin Dachsous1b Interacts with Ttc28 and Aurora B to Control Microtubule Dynamics in Embryonic Cleavages.” Dev Cell. 2018 May 7;45(3):376-391.e5. doi: 10.1016/j.devcel.2018.04.009. (Abstract)