Song J.G., King M.R., Zhang R., Kadzik R.S., Thawani A., & Petry S. (2018) “Mechanism of how augmin directly targets the γ-tubulin ring complex to microtubules.” J Cell Biol. 2018 Jul 2;217(7):2417-2428. doi: 10.1083/jcb.201711090. Epub 2018 Jun 6. (Abstract)
Author: Nicholas Caito
On May 24, 2018, Mr. Darrell Baldwin received the Washington University School of Medicine 2018 Operations Staff Service Award.
The Operations Staff Service award is given to a staff member who has demonstrated outstanding leadership, exceptional performance in their position and superior service.
The department surprised Darrell with an award ceremony and celebration in the seminar room where Dr. David Perlmutter, Dean of the Medical School, said a few words and presented Darrell with his award.
Weber G., DeKoster G.T., Holton N., Hall K.B., & Wahl M.C. (2018). “Molecular principles underlying dual RNA specificity in the Drosophila SNF protein.” Nat Commun. 2018 Jun 7;9(1):2220. doi: 10.1038/s41467-018-04561-6. (Abstract)
Allosteric Coupling of CARMIL and V-1 Binding to Capping Protein Revealed by Hydrogen-Deuterium Exchange.
Johnson B., McConnell P., Kozlov A.G., Mekel M., Lohman T.M., Gross M.L., Amarasinghe G.K., & Cooper J.A. (2018). “Allosteric Coupling of CARMIL and V-1 Binding to Capping Protein Revealed by Hydrogen-Deuterium Exchange.” Cell Rep. 2018 May 29;23(9):2795-2804. doi: 10.1016/j.celrep.2018.04.096. (Abstract)
Ms. Melissa Budelier and Ms. Lucy Li were awarded the 2018 Ceil M. DeGutis Prize in Chemical Biology/Medicinal Chemistry.
On May 22nd, 2018, Ms. Melissa Budelier and Ms. Lucy Li were awarded the 2018 Ceil M. DeGutis Prize in Chemical Biology/Medicinal Chemistry.
Ms. Budelier presented her research entitled “Mapping Ligand Binding Sites in Integral Membrane Proteins”. Ms. Budelier was a graduate student in the Biochemistry, Biophysics and Structural Biology Program. Ms. Budelier was nominated by her thesis mentor Dr. Alex Evers. In Dr. Evers lab, Melissa’s work focused on developing chemical biology tools and mass spectrometric (MS) methods to sequence the transmembrane domains (TMDs) of integral membrane proteins (IMPs) and identified the sites at which sterol analogue photoaffinity labeling reagents modify these proteins. (more…)
Tyagi R., Maddirala A.R., Elfawal M., Fischer C., Bulman C.A., Rosa B.A., Gao X., Chugani R., Zhou M., Helander J., Brindley P.J., Tseng C.C., Greig I.R., Sakanari J., Wildman S.A., Aroian R., Janetka J.W., & Mitreva M. (2018). “Small Molecule Inhibitors of Metabolic Enzymes Repurposed as a New Class of Anthelmintics.” ACS Infect Dis. 2018 May 14. doi: 10.1021/acsinfecdis.8b00090. (Abstract)
Kinch M.S. & Griesenauer R.H. (2018). “2017 in review: FDA approvals of new molecular entities.” Drug Discov Today. 2018 May 8. pii: S1359-6446(18)30088-6. doi: 10.1016/j.drudis.2018.05.011. (Abstract)
Atypical Cadherin Dachsous1b Interacts with Ttc28 and Aurora B to Control Microtubule Dynamics in Embryonic Cleavages.
Chen J., Castelvecchi G.D., Li-Villarreal N., Raught B., Krezel A.M., McNeill H., & Solnica-Krezel L. (2018). “Atypical Cadherin Dachsous1b Interacts with Ttc28 and Aurora B to Control Microtubule Dynamics in Embryonic Cleavages.” Dev Cell. 2018 May 7;45(3):376-391.e5. doi: 10.1016/j.devcel.2018.04.009. (Abstract)
May 2nd, 2018 – Andrea Soranno, PhD, Assistant Professor of Biochemistry and Molecular Biophysics received a Knight ADRC Pilot Grant award from the Alzheimer’s Disease Research Center (ADRC) for his work entitled “Conformational analysis of ApoE and its role in AD mechanism”.