Author: Nicholas Caito

Molecular determinants of evolutionary conservation in disordered protein regions

Oct 1st 2022 – Alex Holehouse, assistant professor of biochemistry and molecular has received $380,000 in funding from the Human Frontiers Science Program (HFSP) to lead a three-year project titled “Molecular determinants of evolutionary conservation in disordered protein regions”. This project will integrate computational and experimental approaches to uncover who intrinsically disordered protein regions evolve. The proposal involves co-investigators Dr. Hyun Kate Lee (University of Toronto, CA) and Dr. Dolf Weijers (Wageningen University, NL).

Molecular engineering to understand desiccation protection and water responsiveness.

Oct 1st 2022 – Alex Holehouse, assistant professor of biochemistry and molecular has received more than $450,000 in funding from the National Science Foundation (NSF) to lead a five-year project titled “Molecular engineering to understand desiccation protection and water responsiveness.” The project is part of a larger grant called “Life without water: protecting macromolecules, cells, and organisms during desiccation and rehydration across kingdoms of life.” This grant establishes the Water and Life Interface Institute led by Carnegie Science (https://www.walii.science/). The new initiative includes collaborators from at least nine research institutions nationwide.