Author: Conrad Weiland

Insights into post-translational regulation of skeletal muscle contractile function by the acetyltransferases, p300 and CBP

Gretchen A Meyer, Jeremie L A Ferey, James A Sanford, Liam S Fitzgerald, Akiva E Greenberg, Kristoffer Svensson, Michael J Greenberg, & Simon Schenk (2024). “Insights into post-translational regulation of skeletal muscle contractile function by the acetyltransferases, p300 and CBP” bioRxiv [Preprint]. 2024 Feb 29:2024.02.27.582179. doi: 10.1101/2024.02.27.582179. (Abstract)

CRISPR Activation Reverses Haploinsufficiency and Functional Deficits Caused by TTN Truncation Variants

Shahnaz Ghahremani, Aditya Kanwal, Anthony Pettinato, Feria Ladha, Nicholas Legere, Ketan Thakar, Yanfen Zhu, Harianto Tjong, Andrea Wilderman, W Tom Stump, Lina Greenberg, Michael J Greenberg, Justin Cotney, Chia-Lin Wei, & J Travis Hinson (2024). “CRISPR Activation Reverses Haploinsufficiency and Functional Deficits Caused by TTN Truncation Variants” Circulation. 2024 Apr 16;149(16):1285-1297. doi: 10.1161/CIRCULATIONAHA.123.063972. Epub 2024 Jan 18. (Abstract)

Rrm3 and Pif1 division of labor during replication through leading and lagging strand G-quadruplex

Mor Varon, Daniel Dovrat, Jonathan HeuzĂ©, Ioannis Tsirkas, Saurabh P Singh, Philippe Pasero, Roberto Galletto, & Amir Aharoni (2024). “Rrm3 and Pif1 division of labor during replication through leading and lagging strand G-quadruplex” Nucleic Acids Res. 2024 Feb 28;52(4):1753-1762. doi: 10.1093/nar/gkad1205. (Abstract)

Mycobacterium tuberculosis Ku Stimulates Multi-round DNA Unwinding by UvrD1 Monomers

Ankita Chadda, Alexander G Kozlov, Binh Nguyen, Timothy M Lohman, & Eric A Galburt (2024). “Mycobacterium tuberculosis Ku Stimulates Multi-round DNA Unwinding by UvrD1 Monomers” J Mol Biol. 2024 Jan 15;436(2):168367. doi: 10.1016/j.jmb.2023.168367. Epub 2023 Nov 14. (Abstract)

High-throughput, fluorescent-aptamer-based measurements of steady-state transcription rates for the Mycobacterium tuberculosis RNA polymerase

Drake Jensen, Ana Ruiz Manzano, Maxwell Rector, Eric J Tomko, M Thomas Record, & Eric A Galburt (2023). “High-throughput, fluorescent-aptamer-based measurements of steady-state transcription rates for the Mycobacterium tuberculosis RNA polymerase” J Cell Biol. 2024 Jan 1;223(1):e202312031. doi: 10.1083/jcb.202312031. Epub 2023 Dec 12. (Abstract)

Biophysical Mechanism of Allosteric Regulation of Actin Capping Protein

Olivia L Mooren, Melissa D Stuchell-Brereton, Patrick McConnell, Chenbo Yan, Emily M Wilkerson, Dennis Goldfarb, John A Cooper, David Sept, & Andrea Soranno (2023). “Biophysical Mechanism of Allosteric Regulation of Actin Capping Protein” J Mol Biol. 2023 Dec 15;435(24):168342. doi: 10.1016/j.jmb.2023.168342. Epub 2023 Nov 2. (Abstract)

Congratulations to Jinping Yang for receiving the 2023 Ceil M. DeGutis Prize Fellows Award

Jinping Yang Jinping Yang is a 5th year PhD student from the Department of Chemistry. She grew up in a small town in China, where she discovered her passion for chemistry during high school. Intrigued by the profound interconnection between chemistry and the fundamental aspects of life, Jinping decided to pursue her undergraduate degree in chemistry and was supported by the Top-Notch Student Cultivation in Math and Sciences Scholarship at Xiamen University. (more…)