CRISPR Activation Reverses Haploinsufficiency and Functional Deficits Caused by TTN Truncation Variants
Shahnaz Ghahremani, Aditya Kanwal, Anthony Pettinato, Feria Ladha, Nicholas Legere, Ketan Thakar, Yanfen Zhu, Harianto Tjong, Andrea Wilderman, W Tom Stump, Lina Greenberg, Michael J Greenberg, Justin Cotney, Chia-Lin Wei, & J Travis Hinson (2024). “CRISPR Activation Reverses Haploinsufficiency and Functional Deficits Caused by TTN Truncation Variants” Circulation. 2024 Apr 16;149(16):1285-1297. doi: 10.1161/CIRCULATIONAHA.123.063972. Epub 2024 Jan 18. (Abstract)
Jinping Yang is a 5th year PhD student from the Department of Chemistry. She grew up in a small town in China, where she discovered her passion for chemistry during high school. Intrigued by the profound interconnection between chemistry and the fundamental aspects of life, Jinping decided to pursue her undergraduate degree in chemistry and was supported by the Top-Notch Student Cultivation in Math and Sciences Scholarship at Xiamen University. 
Jasmine Cubuk is a recent graduate in the Biochemistry, Biophysics, and Structural Biology (BBSB) program. She defended on April 21st, 2023. She did her PhD thesis work in the lab of Dr. Andrea Soranno, where she studied how sequence composition of intrinsically disordered regions within a protein can affect interactions with both proteins and nucleic acids using single-molecule fluorescence spectroscopy.