Author: Conrad Weiland

Stable isotope tracing in vivo reveals a metabolic bridge linking the microbiota to host histone acetylation

Peder J Lund, Leah A Gates, Marylene Leboeuf, Sarah A Smith, Lillian Chau, Mariana Lopes, Elliot S Friedman, Yedidya Saiman, Min Soo Kim, Clarissa A Shoffler, Christopher Petucci, C David Allis, Gary D Wu & Benjamin A Garcia (2022). “Stable isotope tracing in vivo reveals a metabolic bridge linking the microbiota to host histone acetylation” Cell Rep. 2022 Dec 13;41(11):111809. doi: 10.1016/j.celrep.2022.111809. (Abstract)

Permethylation of Ribonucleosides Provides Enhanced Mass Spectrometry Quantification of Post-Transcriptional RNA Modifications

Yixuan Xie, Kevin A Janssen, Alessandro Scacchetti, Elizabeth G Porter, Zongtao Lin, Roberto Bonasio & Benjamin A Garcia (2022). “Permethylation of Ribonucleosides Provides Enhanced Mass Spectrometry Quantification of Post-Transcriptional RNA Modifications” Anal Chem. 2022 May 24;94(20):7246-7254. doi: 10.1021/acs.analchem.2c00471. Epub 2022 May 12. (Abstract)

Epigenomic Reordering Induced by Polycomb Loss Drives Oncogenesis but Leads to Therapeutic Vulnerabilities in Malignant Peripheral Nerve Sheath Tumors

John B Wojcik, Dylan M Marchione, Simone Sidoli, Anissa Djedid, Amanda Lisby, Jacek Majewski & Benjamin A Garcia (2019). “Epigenomic Reordering Induced by Polycomb Loss Drives Oncogenesis but Leads to Therapeutic Vulnerabilities in Malignant Peripheral Nerve Sheath Tumors” Cancer Res. 2019 Jul 1;79(13):3205-3219. doi: 10.1158/0008-5472.CAN-18-3704. Epub 2019 Mar 21. (Abstract)

Single Cell Proteomics by Data-Independent Acquisition To Study Embryonic Asymmetry in Xenopus laevis

Anumita Saha-Shah, Melody Esmaeili, Simone Sidoli, Hyojeong Hwang, Jing Yang, Peter S Klein & Benjamin A Garcia (2019). “Single Cell Proteomics by Data-Independent Acquisition To Study Embryonic Asymmetry in Xenopus laevis” Anal Chem. 2019 Jul 16;91(14):8891-8899. doi: 10.1021/acs.analchem.9b00327. Epub 2019 Jun 27. (Abstract)

One minute analysis of 200 histone posttranslational modifications by direct injection mass spectrometry

Simone Sidoli, Yekaterina Kori, Mariana Lopes, Zuo-Fei Yuan, Hee Jong Kim, Katarzyna Kulej, Kevin A Janssen, Laura M Agosto, Julia Pinheiro Chagas da Cunha, Andrew J Andrews & Benjamin A Garcia (2019). “One minute analysis of 200 histone posttranslational modifications by direct injection mass spectrometry” Genome Res. 2019 Jun;29(6):978-987. doi: 10.1101/gr.247353.118. Epub 2019 May 23. (Abstract)

Regulation of proline-directed kinases and the trans-histone code H3K9me3/H4K20me3 during human myogenesis

Natarajan V Bhanu, Simone Sidoli, Zuo-Fei Yuan, Rosalynn C Molden & Benjamin A Garcia (2019). “Regulation of proline-directed kinases and the trans-histone code H3K9me3/H4K20me3 during human myogenesis” J Biol Chem. 2019 May 17;294(20):8296-8308. doi: 10.1074/jbc.RA118.004977. Epub 2019 Mar 14. (Abstract)

Hydrogen-Deuterium Exchange Coupled to Top- and Middle-Down Mass Spectrometry Reveals Histone Tail Dynamics before and after Nucleosome Assembly

Kelly R Karch, Mariel Coradin, Levani Zandarashvili, Zhong-Yuan Kan, Morgan Gerace, S Walter Englander, Ben E Black & Benjamin A Garcia (2018). “Hydrogen-Deuterium Exchange Coupled to Top- and Middle-Down Mass Spectrometry Reveals Histone Tail Dynamics before and after Nucleosome Assembly” Structure. 2018 Dec 4;26(12):1651-1663.e3. doi: 10.1016/j.str.2018.08.006. Epub 2018 Oct 4. (Abstract)

Characterization of histone acylations links chromatin modifications with metabolism

Johayra Simithy, Simone Sidoli, Zuo-Fei Yuan, Mariel Coradin, Natarajan V Bhanu, Dylan M Marchione, Brianna J Klein, Gleb A Bazilevsky, Cheryl E McCullough, Robert S Magin, Tatiana G Kutateladze, Nathaniel W Snyder, Ronen Marmorstein & Benjamin A Garcia (2017). “Characterization of histone acylations links chromatin modifications with metabolism” Nat Commun. 2017 Oct 26;8(1):1141. doi: 10.1038/s41467-017-01384-9. (Abstract)