Author: Conrad Weiland

2024 BMB Seed Grant Program

The mission of the BMB Research Seed Grant Program is to promote BMB researchers at all levels to develop new avenues of research and/or collaborations that extend beyond their lab’s current research. The BMB Research Seed grant program goal is to stimulate new interactions with external scientists outside of the department.
A broad spectrum of proposal topics will be considered including fundamental studies in biochemistry/biophysics as well as more applied or disease-oriented studies that utilize quantitative or mechanistic approaches as a central component of the research.

Please click the link for more eligibility and application requirements. Application deadline is May 1st

Congratulations to Dept. Chair Dr. Benjamin Garcia for the following achievements:

Dr. Benjamin Garcia2024 ASMS DEIA Mentorship Award
The Diversity, Equity, Inclusion, and Accessibility (DEIA) Mentorship Award recognizes Dr. Garcia who has demonstrated exemplary service in the STEM mentoring and/or recruitment of individuals from groups that are underrepresented in the field of mass spectrometry.

2024 EAS Mass Spectrometry Award
Each year the Eastern Analytical Symposium honors Analytical Chemists who have distinguished career achievements. Dr. Garcia has been recognized for this award by advancing these fields by superior work in developing theory, techniques or instrumentation.

President-Elect of the U.S. Human Proteome Organization
US HUPO is an organization that engages in scientific and educational activities to encourage the use of proteomics technologies and to disseminate knowledge pertaining to the human proteome and that of model organisms.

Congratulations to Daniel Griffith for being selected as the 2024 MilliporeSigma Fellowship

Dan is a fifth-year graduate student in the Computational & Systems Biology (CSB) program. He is completing his Ph.D. in the lab of Dr. Alex Holehouse, Assistant Professor in the Department of Biochemistry & Molecular Biophysics, where he develops computational and experimental tools for investigating intrinsically disordered proteins and biomolecular condensates. (more…)

Congratulations to Tessa Lochetto for being selected for the 2024 Elliot L. Elson Education and Training Award

Tessa Lochetto Tessa is a third-year graduate student in the Molecular Cell Biology (MCB) program. She joined DBBS in 2021 and chose to pursue her PhD thesis work in the lab of Dr. Natalie Niemi, where she studies how dysregulated mitochondrial protein phosphorylation influences the form and function of striated muscle. Specifically, Tessa addresses how hyperphosphorylation of mitochondrial proteins contributes to pathophysiology and tissue dysfunction in cardiac and skeletal muscles using cellular and murine models. (more…)

Congratulations to Madison Stringer for being selected for the 2024 Elliot L. Elson Education and Training Award

Madison StringerMadison is a second-year graduate student in the Biochemistry, Biophysics, and Structural Biology (BBSB) program. She joined the BBSB program after receiving her B.A. in Biochemistry and Biophysics and M.Sc. in Biological Chemistry from the University of Pennsylvania. Her previous work focused on developing protein biosensors to be utilized for 129Xe Nuclear Magnetic Resonance Spectroscopy and Imaging in the lab of Dr. Ivan Dmochowski. (more…)

Expanding the Epitranscriptomic RNA Sequencing and Modification Mapping Mass Spectrometry Toolbox with Field Asymmetric Waveform Ion Mobility and Electrochemical Elution Liquid Chromatography

Richard Lauman, Hee Jong Kim, Lindsay K Pino, Alessandro Scacchetti, Yixuan Xie, Faith Robison, Simone Sidoli, Roberto Bonasio & Benjamin A Garcia (2023). “Expanding the Epitranscriptomic RNA Sequencing and Modification Mapping Mass Spectrometry Toolbox with Field Asymmetric Waveform Ion Mobility and Electrochemical Elution Liquid Chromatography” Anal Chem. 2023 Mar 28;95(12):5187-5195. doi: 10.1021/acs.analchem.2c04114. Epub 2023 Mar 14. (Abstract)

In utero pulse injection of isotopic amino acids quantifies protein turnover rates during murine fetal development

Josue Baeza, Barbara E. Coons, Zongtao Lin, John Riley, Mariel Mendoza, William H. Peranteau & Benjamin A Garcia (2024). “In utero pulse injection of isotopic amino acids quantifies protein turnover rates during murine fetal development” Cell Rep Methods. 2024 Feb 26;4(2):100713. doi: 10.1016/j.crmeth.2024.100713. (Abstract)

An Optimized and High-Throughput Method for Histone Propionylation and Data-Independent Acquisition Analysis for the Identification and Quantification of Histone Post-translational Modifications

Richard M Searfoss, Rashmi Karki, Zongtao Lin, Faith Robison & Benjamin A Garcia (2023). “An Optimized and High-Throughput Method for Histone Propionylation and Data-Independent Acquisition Analysis for the Identification and Quantification of Histone Post-translational Modifications” J Am Soc Mass Spectrom. 2023 Nov 1;34(11):2508-2517. doi: 10.1021/jasms.3c00223. Epub 2023 Oct 18. (Abstract)

SWAMNA: a comprehensive platform for analysis of nucleic acid modifications

Yixuan Xie, Francisca N. De Luna Vitorino, Ye Chen, Joanna K. Lempiäinen, Chenfeng Zhao, Robert T. Steinbock, Zongtao Lin, Xingyu Liu, Emily Zahn, Arabella L. Garcia, Matthew D. Weitzmancd & Benjamin A Garcia (2023). “SWAMNA: a comprehensive platform for analysis of nucleic acid modifications” Chem Commun. 2023, 59(83):12499-12502. (Abstract)