Category: Galburt Publications

TFIIH generates a six-base-pair open complex during RNAP II transcription initiation and start-site scanning.

Tomko E.J., Fishburn J., Hahn S., & Galburt E.A. (2017). “TFIIH generates a six-base-pair open complex during RNAP II transcription initiation and start-site scanning.” Nat Struct Mol Biol. 2017 Dec;24(12):1139-1145. doi: 10.1038/nsmb.3500. Epub 2017 Nov 6. (Abstract)

Effects of Increasing the Affinity of CarD for RNA Polymerase on Mycobacterium tuberculosis Growth, rRNA Transcription, and Virulence.

Garner A.L., Rammohan J., Huynh J.P., Onder L.M., Chen J., Bae B., Jensen D., Weiss L.A., Ruiz Manzano A., Darst S.A., Campbell E.A., Nickels B.E., Galburt E.A., & Stallings C.L. (2016). “Effects of Increasing the Affinity of CarD for RNA Polymerase on Mycobacterium tuberculosis Growth, rRNA Transcription, and Virulence.” J Bacteriol. 2017 Jan 30;199(4). pii: e00698-16. doi: 10.1128/JB.00698-16. Print 2017 Feb 15. (Abstract)

A Kinetic Signature for Parallel Pathways: Conformational Selection and Induced Fit. Links and Disconnects between Observed Relaxation Rates and Fractional Equilibrium Flux under Pseudo-First-Order Conditions.

Galburt E.A. & Rammohan J. (2016). “A Kinetic Signature for Parallel Pathways: Conformational Selection and Induced Fit. Links and Disconnects between Observed Relaxation Rates and Fractional Equilibrium Flux under Pseudo-First-Order Conditions.” Biochemistry. 2016 Dec 20;55(50):7014-7022. Epub 2016 Dec 8. (Abstract)

Cooperative stabilization of Mycobacterium tuberculosis rrnAP3 promoter open complexes by RbpA and CarD.

Rammohan J., Ruiz Manzano A., Garner A.L., Prusa J. Stallings C.L., & Galburt E.A. (2016). “Cooperative stabilization of Mycobacterium tuberculosis rrnAP3 promoter open complexes by RbpA and CarD.” Nucleic Acids Res. 2016 Sep 6;44(15):7304-13. doi: 10.1093/nar/gkw577. Epub 2016 Jun 24. (Abstract)

Transcription Start Site Scanning and the Requirement for ATP during Transcription Initiation by RNA Polymerase II.

Fishburn J., Galburt E., & Hahn S. (2016). “Transcription Start Site Scanning and the Requirement for ATP during Transcription Initiation by RNA Polymerase II.” J Biol Chem. 2016 Jun 17;291(25):13040-7. doi: 10.1074/jbc.M116.724583. Epub 2016 Apr 17. (Abstract)

Double-stranded DNA translocase activity of transcription factor TFIIH and the mechanism of RNA polymerase II open complex formation.

Fishburn J., Tomko E., Galburt E., & Hahn S. (2015). “Double-stranded DNA translocase activity of transcription factor TFIIH and the mechanism of RNA polymerase II open complex formation.” Proc Natl Acad Sci U S A. 2015 Mar 31;112(13):3961-6. doi: 10.1073/pnas.1417709112. Epub 2015 Mar 16. (Abstract)