Spotlight on Research – Li Lab
The Li Lab studies the structure and function of integral membrane proteins, with a focus on ones that are important for hematologic and cardiovascular systems. We use a variety of structural biology, biochemistry, cell biology and mass spectrometry techniques to understand the structural mechanism of these membrane proteins. Structural insights give us a novel angle to elucidate the actions of these proteins in cellular settings. Deep understanding of protein structure and function often has implications significant for human disease. In addition, these proteins provide challenges that motivate us to develop new structural and biochemical methods broadly applicable to membrane biology.
