Biography:
Emma received her B.S. in Biochemistry and her B.A. in Microbiology from Indiana University in Bloomington. After graduation, Emma joined the Medical Scientist Training Program at Washington University in St. Louis where she became part of the Immunology program in the Division of Biology and Biomedical Sciences for her graduate studies. (more…)
Biography:
Sarah received her undergraduate degree in biochemistry from the Ohio State University and joined the Division of Biological and Biomedical Sciences at Washington University in St. Louis in 2016 as part of the Biochemistry, Biophysics, and Structural Biology. Sarah is completing her thesis work in the lab of Dr. Michael Greenberg with her focus being the study of mutations in the protein troponin T which lead to familial cardiomyopathies. (more…)
Seminar Title: Elucidating Enhancer Function in Epidermal Development
Biography
Dr. Mary Elizabeth Mathyer received her B.A. in Biology and Theatre Arts from Kalamazoo College in 2014. After graduation, Dr. Mathyer joined the Molecular Genetics and Genomics program in the Division of Biology and Biomedical Sciences at Washington University in St. Louis. (more…)
Seminar Title: “Highlights from “The degenerating star clock”: Astrocytes, Alzheimer’s disease, and the circadian clock”
Biography:
Dr. Brian Lananna received his B.A. in Psychology from Dartmouth College before joining the Division of Biological and Biomedical Sciences at Washington University as a Neuroscience graduate student in 2014. At Washington University, Dr. Lananna studied circadian clock regulation of astrocytic and microglial immune activation in the context of aging and Alzheimer’s disease in the lab of Dr. Erik Musiek in the department of Neurology. He was able to show that the circadian clock within astrocytes cell autonomously regulates astrocyte activation. Dr. Lananna has also demonstrated that a previously known Alzheimer’s biomarker, Chi3l1 (YKL-40) is regulated in astrocytes by the circadian clock. Further, he discovered that suppression of this protein can suppress beta-amyloid deposition in a mouse model and is associated with slower disease progression in humans with Alzheimer’s disease. Dr. Lananna defended his thesis, entitled “The degenerating star clock: Circadian clock regulation of astrogliosis and implications for Alzheimer’s disease” on April 10, 2019. (more…)
Seminar Title: Yeast cell cycle checkpoint regulation in response to DNA breaks and short telomeres
Biography
Sarem received her undergraduate degree in Biology from Shaw University in Raleigh, North Carolina. She joined the Division of Biological and Biomedical Sciences at Washington University in St. Louis in 2012 as part of the Molecular Cell Biology program. Sarem has always been interested in mechanisms employed by different organisms to maintain genome integrity. Prior to joining DBBS, Sarem worked on the mammalian DNA replication origin-licensing factor, Cdt1. (more…)