Category: Frazier Publications

Dr. Frazier’s Publications

Attenuation of Ischemia-Reperfusion Injury and Improvement of Survival in Recipients of Steatotic Rat Livers Using CD47 Monoclonal Antibody.

Xiao Z., Banan B., Xu M., Jia J., Manning P.T., Hiebsch R.R., Gunasekaran M., Upadhya G.A., Frazier W.A., Mohanakumar T., Lin Y., & Chapman W.C. (2016). “Attenuation of Ischemia-Reperfusion Injury and Improvement of Survival in Recipients of Steatotic Rat Livers Using CD47 Monoclonal Antibody.” Transplantation. 2016 Jul;100(7):1480-9. doi: 10.1097/TP.0000000000001186. (Abstract)

Phosphorylation of the BNIP3 C-Terminus Inhibits Mitochondrial Damage and Cell Death without Blocking Autophagy.

Liu K.E. & Frazier W.A. (2015). “Phosphorylation of the BNIP3 C-Terminus Inhibits Mitochondrial Damage and Cell Death without Blocking Autophagy.” PLoS One. 2015 Jun 23;10(6):e0129667. doi: 10.1371/journal.pone.0129667. eCollection 2015. (Abstract)

Antibody mediated therapy targeting CD47 inhibits tumor progression of hepatocellular carcinoma.

Xiao Z.Y., Chung H., Banan B., Manning P.T., Ott K.C., Lin S., Capoccia B.J., Subramanian V., Hiebsch R.R., Upadhya G., Mohanakumar T., Frazier W.A., Lin Y., & Chapman W.C. (2015). “Antibody mediated therapy targeting CD47 inhibits tumor progression of hepatocellular carcinoma.” Cancer Lett. 2015 May 1;360(2):302-9. doi: 10.1016/j.canlet.2015.02.036. Epub 2015 Feb 23. (Abstract)

Thrombospondin-1 regulates bone homeostasis through effects on bone matrix integrity and nitric oxide signaling in osteoclasts.

Amend S.R., Uluckan O., Hurchla M., Leib D., Novack D.V., Silva M., Frazier W., & Weilbaecher K.N. (2015). “Thrombospondin-1 regulates bone homeostasis through effects on bone matrix integrity and nitric oxide signaling in osteoclasts.” J Bone Miner Res. 2015 Jan;30(1):106-15. doi: 10.1002/jbmr.2308. (Abstract)

CD47 blockade reduces ischemia/reperfusion injury and improves survival in a rat liver transplantation model.

Xiao Z.Y., Banan B., Jia J., Manning P.T., Hiebsch R.R., Gunasekaran M., Upadhya G., Frazier W.A., Mohanakumar T., & Chapman W.C. (2015). “CD47 blockade reduces ischemia/reperfusion injury and improves survival in a rat liver transplantation model.” Liver Transpl. 2015 Apr;21(4):468-477. doi: 10.1002/lt.24059. Epub 2015 Jan 29. (Abstract)

CD47 blockade reduces ischemia-reperfusion injury and improves outcomes in a rat kidney transplant model.

Lin Y., Manning P.T., Jia J., Gaut J.P., Xiao Z., Capoccia B.J., Chen C.C., Hiebsch R.R., Upadhya G., Mohanakumar T., Frazier W.A., & Chapman W.C. (2014). “CD47 blockade reduces ischemia-reperfusion injury and improves outcomes in a rat kidney transplant model.” Transplantation. 2014 Aug 27;98(4):394-401. doi: 10.1097/TP.0000000000000252. (Abstract)

CD47 plays a critical role in T-cell recruitment by regulation of LFA-1 and VLA-4 integrin adhesive functions.

Azcutia V., Routledge M., Williams M.R., Newton G., Frazier W.A., Manica A., Croce K.J., Parkos C.A., Schmider A.B., Turman M.V., Soberman R.J., & Luscinskas F.W. (2013). “CD47 plays a critical role in T-cell recruitment by regulation of LFA-1 and VLA-4 integrin adhesive functions.” Mol Biol Cell. 2013 Nov;24(21):3358-68. doi: 10.1091/mbc.E13-01-0063. Epub 2013 Sep 4. (Abstract)

Inhibitory signaling through signal regulatory protein-α is not sufficient to explain the antitumor activities of CD47 antibodies.

Soto-Pantoja D.R., Miller T.W., Frazier W.A., & Roberts D.D. (2012). “Inhibitory signaling through signal regulatory protein-α is not sufficient to explain the antitumor activities of CD47 antibodies.” Proc Natl Acad Sci U S A. 2012 Oct 16;109(42):E2842; author reply E2844-5. doi: 10.1073/pnas.1205441109. Epub 2012 Aug 24. (Abstract)