Category: Galletto Publications

Dr. Galletto’s Publications

The signature motif of the Saccharomyces cerevisiae Pif1 DNA helicase is essential in vivo for mitochondrial and nuclear functions and in vitro for ATPase activity.

Geronimo C.L., Singh S.P., Galletto R., & Zakian V.A. (2018). “The signature motif of the Saccharomyces cerevisiae Pif1 DNA helicase is essential in vivo for mitochondrial and nuclear functions and in vitro for ATPase activity.” Nucleic Acids Res. 2018 Sep 19;46(16):8357-8370. doi: 10.1093/nar/gky655. (Abstract)

The mitochondrial single-stranded DNA binding protein from S. cerevisiae, Rim1, does not form stable homo-tetramers and binds DNA as a dimer of dimers.

Singh S.P., Kukshal V., De Bona P., Antony E., & Galletto R. (2018). “The mitochondrial single-stranded DNA binding protein from S. cerevisiae, Rim1, does not form stable homo-tetramers and binds DNA as a dimer of dimers.” Nucleic Acids Res. 2018 Jun 21. doi: 10.1093/nar/gky530. (Abstract)

Pif1 removes a Rap1-dependent barrier to the strand displacement activity of DNA polymerase δ.

Koc K.N., Singh S.P., Stodola J.L., Burgers P.M., & Galletto R. (2016). “Pif1 removes a Rap1-dependent barrier to the strand displacement activity of DNA polymerase δ.” Nucleic Acids Res. 2016 May 5;44(8):3811-9. doi: 10.1093/nar/gkw181. Epub 2016 Mar 21. (Abstract)

Singh, S.P., Koc, K.N., Stodola, J.L. and Galletto, R.
A Monomer of Pif1 Unwinds Double-Stranded DNA and It Is Regulated by the Nature of the Non-Translocating Strand at the 3′-End.
J Mol Biol 428:1053-1067 (2016). (Abstract)