Category: Research Awards

All Research Awards

Targeting a transcriptional co-repressor to prevent photoreceptor degeneration

January 1st, 2024 – Alex Holehouse, PhD Assistant Professor in the Department of Biochemistry and Molecular Biophysics, along with Joe Corbo, MD, PhD, in the Department of Pathology and Immunology, received a new two-year grant award from the Hope Center entitled “Targeting a transcriptional co-repressor to prevent photoreceptor degeneration.”

Uncovering the regulatory logic of gene expression encoded by disordered regions

September 1st, 2023 – Alex Holehouse, PhD, Assistant Professor in the Department of Biochemistry and Molecular Biophysics, received a 2023 NIH New Innovator Award. This five-year award from the National Institute of Health, administered through the National Cancer Institute, is entitled “Uncovering the regulatory logic of gene expression encoded by disordered regions.”.

Innovative therapeutic strategies to support elimination of river blindness

September 11th, 2023 – James Janetka, PhD, Professor in the Department of Biochemistry and Molecular Biophysics along with Makedonka Mitreva, PhD, Medicine of Medicine and Genetics, received a new four-year grant award from the National Institute of Allergy and Infectious Diseases, National Institutes of Health, for their research entitled “Innovative therapeutic strategies to support elimination of river blindness”.

The role of protein phosphorylation in the mitochondrial matrix in determining mitophagic selectivity

August 11th, 2023 – Natalie M. Niemi, PhD, Assistant Professor in the department of Biochemistry and Molecular Biophysics, received a new four-year grant award from Molecular and Cellular Biosciences Core Programs of the National Science Federation for her research entitled “The role of protein phosphorylation in the mitochondrial matrix in determining mitophagic selectivity”.

Delineating phosphorylation-mediated regulation of mitochondrial function

August 11th, 2023 – Natalie M. Niemi, PhD, Assistant Professor in the department of Biochemistry and Molecular Biophysics, received a new five-year MIRA grant award from National Institute of General Medical Sciences for her research entitled “Delineating phosphorylation-mediated regulation of mitochondrial function”.

Investigating mitochondrial protein phosphorylation in NAFLD and NASH

August 11th, 2023 – Natalie M. Niemi, PhD, Assistant Professor in the department of Biochemistry and Molecular Biophysics, received a one-year grant award from the Washington University Digestive Disease Research Core Center (DDRCC), sponsored by the National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) for her research entitled “Investigating mitochondrial protein phosphorylation in NAFLD and NASH”.

Molecular determinants of evolutionary conservation in disordered protein regions

Oct 1st 2022 – Alex Holehouse, assistant professor of biochemistry and molecular has received $380,000 in funding from the Human Frontiers Science Program (HFSP) to lead a three-year project titled “Molecular determinants of evolutionary conservation in disordered protein regions”. This project will integrate computational and experimental approaches to uncover who intrinsically disordered protein regions evolve. The proposal involves co-investigators Dr. Hyun Kate Lee (University of Toronto, CA) and Dr. Dolf Weijers (Wageningen University, NL).

Molecular engineering to understand desiccation protection and water responsiveness.

Oct 1st 2022 – Alex Holehouse, assistant professor of biochemistry and molecular has received more than $450,000 in funding from the National Science Foundation (NSF) to lead a five-year project titled “Molecular engineering to understand desiccation protection and water responsiveness.” The project is part of a larger grant called “Life without water: protecting macromolecules, cells, and organisms during desiccation and rehydration across kingdoms of life.” This grant establishes the Water and Life Interface Institute led by Carnegie Science (https://www.walii.science/). The new initiative includes collaborators from at least nine research institutions nationwide.

Quantitative mass spectrometry for comprehending epigenetic mechanisms in a new underlying neurological developmental disorder

August 16th, 2022 – Benjamin Garcia, PhD, Raymond H. Wittcoff Distinguished Professor and Head of Biochemistry and Molecular Biophysics, along with Elizabeth Bhoj, MD, PhD, Assistant Professor of Pediatrics, University of Pennsylvania of Medicine and Children’s Hospital of Philadelphia received a five year grant from the National Institutes of Health for their research entitled “Quantitative mass spectrometry for comprehending epigenetic mechanisms in a new underlying neurological developmental disorder”.