Author: Nicholas Caito

Treatment and prevention of urinary tract infection with orally active FimH inhibitors.

Cusumano C.K., Pinkner J.S., Han Z., Greene S.E., Ford B.A., Crowley J.R., Henderson J.P., Janetka J.W., and Hultgren S.J.
Treatment and prevention of urinary tract infection with orally active FimH inhibitors.
Sci Transl Med. 3(109):109ra115. doi: 10.1126/scitranslmed.3003021. (2011) (Abstract)

Hydrogen/deuterium exchange and electron-transfer dissociation mass spectrometry determine the interface and dynamics of apolipoprotein E oligomerization.

Huang R.Y., Garai K., Frieden C., & Gross M.L. (2011). “Hydrogen/deuterium exchange and electron-transfer dissociation mass spectrometry determine the interface and dynamics of apolipoprotein E oligomerization.” Biochemistry. 2011 Nov 1;50(43):9273-82. doi: 10.1021/bi2010027. Epub 2011 Oct 5. (Abstract)

The unstructured C-terminal tail of yeast Dpb11 (human TopBP1) protein is dispensable for DNA replication and the S phase checkpoint but required for the G2/M checkpoint.

Navadgi-Patil, V.M., Kumar, S. and Burgers, P.M.
The unstructured C-terminal tail of yeast Dpb11 (human TopBP1) protein is dispensable for DNA replication and the S phase checkpoint but required for the G2/M checkpoint.
J Biol Chem 286:40999-41007 (2011). (Abstract)

Mass spectrometry-based protein footprinting characterizes the structures of oligomeric apolipoprotein E2, E3, and E4.

Gau B.C., Garai K., Frieden C., & Gross M.L. (2011). “Mass spectrometry-based protein footprinting characterizes the structures of oligomeric apolipoprotein E2, E3, and E4.” Biochemistry. 2011 Sep 27;50(38):8117-26. doi: 10.1021/bi200911c. Epub 2011 Sep 2. (Abstract)

Diffusion of MMPs on the surface of collagen fibrils: the mobile cell surface-collagen substratum interface.

Collier I.E., Legant W., Marmer B., Lubman O., Saffarian S., Wakatsuki T., Elson E., & Goldberg G.I. (2011). “Diffusion of MMPs on the surface of collagen fibrils: the mobile cell surface-collagen substratum interface.” PLoS One. 2011;6(9):e24029. doi: 10.1371/journal.pone.0024029. Epub 2011 Sep 1. (Abstract)

Drug-like leads for steric discrimination between substrate and inhibitors of human acetylcholinesterase.

Wildman S.A., Zheng X., Sept D., Auletta J.T., Rosenberry T.L., and Marshall G.R. (2011) “Drug-like leads for steric discrimination between substrate and inhibitors of human acetylcholinesterase.” Chem Biol Drug Des. 2011 Oct;78(4):495-504. doi: 10.1111/j.1747-0285.2011.01157.x. Epub 2011 Aug 22. (Abstract)