Category: Bowman Publications

Dr. Bowman’s Publications

Designing small molecules to target cryptic pockets yields both positive and negative allosteric modulators.

Hart K.M., Moeder K.E., Ho C.M.W., Zimmerman M.I., Frederick T.E., and Bowman G.R.
Designing small molecules to target cryptic pockets yields both positive and negative allosteric modulators.
PLoS One. 12(6):e0178678. doi: 10.1371/journal.pone.0178678. eCollection. (2017) (Abstract)

Warfarin traps human vitamin K epoxide reductase in an intermediate state during electron transfer.

Shen G., Cui W., Zhang H., Zhou F., Huang W., Liu Q., Yang Y., Li S., Bowman G.R., Sadler J.E., Gross M.L., and Li W.
Warfarin traps human vitamin K epoxide reductase in an intermediate state during electron transfer.
Nat Struct Mol Biol. 24(1):69-76. (2017). (Abstract)
Featured in News and Views, Nature Structural & Molecular Biology 24, 5–6. (2017)