Category: All Publications

Structural basis of pH-dependent activation in a CLC transporter

Eva Fortea, Sangyun Lee, Rahul Chadda, Yiorgos Argyros, Priyanka Sandal, Robyn Mahoney-Kruszka, Hatice Didar Ciftci, Maria E Falzone, Gerard Huysmans, Janice L Robertson, Olga Boudker & Alessio Accardi (2024). “Structural basis of pH-dependent activation in a CLC transporter” Nat Struct Mol Biol. 2024 Apr;31(4):644-656. doi: 10.1038/s41594-023-01210-5. Epub 2024 Jan 26. (Abstract)

The disordered N-terminal tail of SARS-CoV-2 Nucleocapsid protein forms a dynamic complex with RNA

Jasmine Cubuk, Jhullian J Alston, J Jeremías Incicco, Alex S Holehouse, Kathleen B Hall, Melissa D Stuchell-Brereton & Andrea Soranno (2024). “The disordered N-terminal tail of SARS-CoV-2 Nucleocapsid protein forms a dynamic complex with RNA” Nucleic Acids Res. 2024 Mar 21;52(5):2609-2624. doi: 10.1093/nar/gkad1215. (Abstract)

A single-molecule method for measuring fluorophore labeling yields for the study of membrane protein oligomerization in membranes

Melanie Ernst, Tugba N Ozturk, Janice L Robertson (2023). “A single-molecule method for measuring fluorophore labeling yields for the study of membrane protein oligomerization in membranes” PLoS One. 2023 Jan 20;18(1):e0280693. doi: 10.1371/journal.pone.0280693. eCollection 2023. (Abstract)

A thermodynamic analysis of CLC transporter dimerization in lipid bilayers

Rahul Chadda, Taeho Lee, Robyn Mahoney-Kruszka, Elizabeth G Kelley, Nathan Bernhardt, Priyanka Sandal & Janice L Robertson (2023). “A thermodynamic analysis of CLC transporter dimerization in lipid bilayers” Proc Natl Acad Sci U S A. 2023 Oct 10;120(41):e2305100120. doi: 10.1073/pnas.2305100120. Epub 2023 Oct 3. (Abstract)

Extracellular domain mutations of the EGF receptor differentially modulate high-affinity and low-affinity responses to EGF receptor ligands

Jennifer L Macdonald-Obermann & Linda J Pike (2024). “Extracellular domain mutations of the EGF receptor differentially modulate high-affinity and low-affinity responses to EGF receptor ligands” J Biol Chem. 2024 Mar;300(3):105763. doi: 10.1016/j.jbc.2024.105763. Epub 2024 Feb 16. (Abstract)

A new twist on PIFE: photoisomerisation-related fluorescence enhancement

Evelyn Ploetz, Benjamin Ambrose, Anders Barth, Richard Börner, Felix Erichson, Achillefs N Kapanidis, Harold D Kim, Marcia Levitus, Timothy M Lohman, Abhishek Mazumder, David S Rueda, Fabio D Steffen, Thorben Cordes, Steven W Magennis & Eitan Lerner (2023). “A new twist on PIFE: photoisomerisation-related fluorescence enhancement” Methods Appl Fluoresc. 2023 Oct 12;12(1):012001. doi: 10.1088/2050-6120/acfb58. (Abstract)

Molecular basis of inherited protein C deficiency results from genetic variations in the signal peptide and propeptide regions

Qing Cao, Zhenyu Hao, Cheng Li, Xuejie Chen, Meng Gao, Nan Jiang, Hongli Liu, Yan Shen, Haiping Yang, Shujuan Zhang, Aiying Yang, Weikai Li, Jian-Ke Tie & Guomin Shen (2023). “Molecular basis of inherited protein C deficiency results from genetic variations in the signal peptide and propeptide regions” J Thromb Haemost. 2023 Nov;21(11):3124-3137. doi: 10.1016/j.jtha.2023.06.021. Epub 2023 Jun 29. (Abstract)