Category: Li Publications

Dr. Li’s Publications

Multimodal mechanisms of pathogenic variants in the signal peptide of FIX leading to hemophilia B

Meng Gao, Long Chen, Jinlong Yang, Shixia Dong, Qing Cao, Zihan Cui, Yanyan Dong, Hongli Liu, Yan Shen, Haiping Yang, Zhenyu Hao, Lei Zhang, Weikai Li, Jian-Ke Tie & Guomin Shen (2024). “Multimodal mechanisms of pathogenic variants in the signal peptide of FIX leading to hemophilia B” Blood Adv.2024 Aug 13;8(15):3893-3905. doi: 10.1182/bloodadvances.2023012432. (Abstract)

Molecular basis of inherited protein C deficiency results from genetic variations in the signal peptide and propeptide regions

Qing Cao, Zhenyu Hao, Cheng Li, Xuejie Chen, Meng Gao, Nan Jiang, Hongli Liu, Yan Shen, Haiping Yang, Shujuan Zhang, Aiying Yang, Weikai Li, Jian-Ke Tie & Guomin Shen (2023). “Molecular basis of inherited protein C deficiency results from genetic variations in the signal peptide and propeptide regions” J Thromb Haemost. 2023 Nov;21(11):3124-3137. doi: 10.1016/j.jtha.2023.06.021. Epub 2023 Jun 29. (Abstract)

The tetraspanin CD53 protects stressed hematopoietic stem cells via promotion of DREAM complex- mediated quiescence

Zev J. Greenberg, Darlene Monlish, Luana Chiquetto Paracatu, Qian Dong, Michael P. Rettig, Nate Dee Roundy, Rofaida Gaballa, Weikai Li, Wei Yang, Cliff J. Luke, & Laura Schuettpelz (2022). “The tetraspanin CD53 protects stressed hematopoietic stem cells via promotion of DREAM complex- mediated quiescence” Blood. 2022 Dec 21;blood.2022016929. doi: 10.1182/blood.2022016929. Online ahead of print. (Abstract)

Stabilization and structure determination of integral membrane proteins by termini restraining

Shixuan Liu, Shuang Li, Andrzej M. Krezel, & Weikai Li (2022). “Stabilization and structure determination of integral membrane proteins by termini restraining” Nat Protoc. 2022 Jan 17. doi: 10.1038/s41596-021-00656-5. Online ahead of print. (Abstract)

Footprinting Mass Spectrometry of Membrane Proteins: Ferroportin Reconstituted in Saposin A Picodiscs

Fengbo Zhou, Yihu Yang, Saketh Chemuru, Weidong Cui, Shixuan Liu, Michael Gross, & Weikai Li (2021). “Footprinting Mass Spectrometry of Membrane Proteins: Ferroportin Reconstituted in Saposin A Picodiscs” Anal Chem. 2021 Aug 24;93(33):11370-11378. doi: 10.1021/acs.analchem.1c02325. Epub 2021 Aug 12. (Abstract)

Free-Radical Membrane Protein Footprinting by Photolysis of Perfluoroisopropyl Iodide Partitioned to Detergent Micelle by Sonication

Ming Cheng, Chunyang Guo, Weikai Li, & Michael L. Gross (2021). “Free-Radical Membrane Protein Footprinting by Photolysis of Perfluoroisopropyl Iodide Partitioned to Detergent Micelle by Sonication” Angew Chem Int Ed Engl. 2021 Mar 10. doi: 10.1002/anie.202014096. Online ahead of print. (Abstract)