Molecular simulation and Markov State Model approaches for folding, binding, and design
2017-10-03 – Vincent Voelz, Ph.D. – Temple University – “Molecular simulation and Markov State Model approaches for folding, binding, and design” (more…)
Author: Nicholas Caito
An overview of FDA-approved vaccines & their innovators.
Griesenauer R.H. & Kinch M.S. (2017). “An overview of FDA-approved vaccines & their innovators.” Expert Rev Vaccines. 2017 Dec;16(12):1253-1266. doi: 10.1080/14760584.2017.1383159. Epub 2017 Sep 25. (Abstract)
Inhibition of calcium dependent protein kinase 1 (CDPK1) by pyrazolopyrimidine analogs decreases establishment and reoccurrence of central nervous system disease by Toxoplasma gondii.
Rutaganira F.U., Barks J., Dhason M.S., Wang Q., Lopez M.S., Long S., Radke J.B., Jones N.G., Maddirala A.R., Janetka J.W., El Bakkouri M., Hui R., Shokat K.M., & Sibley L.D. (2017). “Inhibition of calcium dependent protein kinase 1 (CDPK1) by pyrazolopyrimidine analogs decreases establishment and reoccurrence of central nervous system disease by Toxoplasma gondii.” J Med Chem. 2017 Dec 28;60(24):9976-9989. doi: 10.1021/acs.jmedchem.7b01192. Epub 2017 Oct 9. (Abstract)
Peptide-Level Interactions between Proteins and Small-Molecule Drug Candidates by Two Hydrogen-Deuterium Exchange MS-Based Methods: The Example of Apolipoprotein E3.
Wang H., Rempel D.L., Giblin D., Frieden C., & Gross M.L. (2017). “Peptide-Level Interactions between Proteins and Small-Molecule Drug Candidates by Two Hydrogen-Deuterium Exchange MS-Based Methods: The Example of Apolipoprotein E3.” Anal Chem. 2017 Oct 17;89(20):10687-10695. doi: 10.1021/acs.analchem.7b01121. Epub 2017 Sep 25. (Abstract)
Getting sick of splicing: Alternative Splicing and the Human Immune System
2017-09-19 – Kristen W. Lynch, Ph.D. – University of Pennsylvania – “Getting sick of splicing: Alternative Splicing and the Human Immune System” (more…)
Biophysics and Genome Regulation: Phase Separation Drives Heterochromatin Domain Formation
2017-09-13 – Gary Karpen , Ph.D. – University of California, Berkeley – “Biophysics and Genome Regulation: Phase Separation Drives Heterochromatin Domain Formation” (more…)
From Molecular Dynamics to Genomic Biology: Constructing Kinetic Network Models to Elucidate Transcriptional Fidelity of RNA Polymerase II
2017-09-12 – Xuhui Huang, Ph.D. – The Hong Kong University of Science and Technology – “From Molecular Dynamics to Genomic Biology: Constructing Kinetic Network Models to Elucidate Transcriptional Fidelity of RNA Polymerase II” (more…)
Limiting Assumptions in the Design of Peptidomimetics.
Marshall G.R. & Ballante F. (2017). “Limiting Assumptions in the Design of Peptidomimetics.” Drug Dev Res. 2017 Sep;78(6):245-267. doi: 10.1002/ddr.21406. Epub 2017 Sep 6. (Abstract)
Single-molecule spectroscopy of intrinsically disordered proteins
2017-09-12 – Andrea Soranno, Ph.D. – Single-molecule spectroscopy of intrinsically disordered proteins (more…)
Congratulations to Min Kyung Shinn for being selected for the 2017 Elson Fellowship in honor of Dr. Elliot Elson
Ms. Min Kyung Shinn received her B.A. in physics and chemistry from Bard College in 2014. After graduation, Ms. Shinn joined the PhD program at Washington University in Saint Louis in the department of physics and joined the laboratory of Dr. Tim Lohman. In 2016, Ms. Shinn received her M.A. in physics. (more…)