Mechanical Properties of Single Nonmuscle myosin-2 filaments
2017-02-21 – James R. Sellers, Ph.D. – NIH – “Mechanical Properties of Single Nonmuscle myosin-2 filaments” (more…)
Author: Nicholas Caito
Allostery in the EGF Receptor
2017-03-14 – Linda Pike, Ph.D. – Allostery in the EGF Receptor (more…)
Structural insights of SmKDAC8 inhibitors: Targeting Schistosoma epigenetics through a combined structure-based 3D QSAR, in vitro and synthesis strategy.
Ballante F., Reddy D.R., Zhou N.J., and Marshall G.R. (2017) “Structural insights of SmKDAC8 inhibitors: Targeting Schistosoma epigenetics through a combined structure-based 3D QSAR, in vitro and synthesis strategy.” Bioorg Med Chem. 2017 Apr 1;25(7):2105-2132. doi: 10.1016/j.bmc.2017.02.020. Epub 2017 Feb 13. (Abstract)
HIV Cure, Shock and Kill Versus Block and Lock
2017-02-14 – George Kyei, MBChB, Ph.D. – Washington University in Saint Louis, School of Medicine – “HIV Cure, Shock and Kill Versus Block and Lock” (more…)
Evolutionary fine-tuning of conformational ensembles in FimH during host-pathogen interactions.
Kalas V., Pinkner J.S., Hannan T.J., Hibbing M.E., Dodson K.W., Holehouse A.S., Zhang H., Tolia N.H., Gross M.L., Pappu R.V., Janetka J., & Hultgren S.J. (2017). “Evolutionary fine-tuning of conformational ensembles in FimH during host-pathogen interactions.” Sci Adv. 2017 Feb 10;3(2):e1601944. doi: 10.1126/sciadv.1601944. eCollection 2017 Feb. (Abstract)
Elucidating the Role of Conformational Dynamics in Protein Function with NMR Spectroscopy and Molecular Simulation
2017-02-07 – Paul Robustelli, Ph.D. – D.E. Shaw Research – “Elucidating the Role of Conformational Dynamics in Protein Function with NMR Spectroscopy and Molecular Simulation” (more…)
Conformational selection and induced fit as a useful framework for molecular motor mechanisms.
Galburt E.A. & Tomko E.J. (2017). “Conformational selection and induced fit as a useful framework for molecular motor mechanisms.” Biophys Chem. 2017 Apr;223:11-16. doi: 10.1016/j.bpc.2017.01.004. Epub 2017 Feb 3. (Abstract)
Trojan Horse Transit Contributes to Blood-Brain Barrier Crossing of a Eukaryotic Pathogen.
Santiago-Tirado F.H., Onken M.D., Cooper J.A., Klein R.S., & Doering T.L. (2017). “Trojan Horse Transit Contributes to Blood-Brain Barrier Crossing of a Eukaryotic Pathogen.” MBio. 2017 Jan 31;8(1). pii: e02183-16. doi: 10.1128/mBio.02183-16. (Abstract)
Effects of Increasing the Affinity of CarD for RNA Polymerase on Mycobacterium tuberculosis Growth, rRNA Transcription, and Virulence.
Garner A.L., Rammohan J., Huynh J.P., Onder L.M., Chen J., Bae B., Jensen D., Weiss L.A., Ruiz Manzano A., Darst S.A., Campbell E.A., Nickels B.E., Galburt E.A., & Stallings C.L. (2016). “Effects of Increasing the Affinity of CarD for RNA Polymerase on Mycobacterium tuberculosis Growth, rRNA Transcription, and Virulence.” J Bacteriol. 2017 Jan 30;199(4). pii: e00698-16. doi: 10.1128/JB.00698-16. Print 2017 Feb 15. (Abstract)
Quantitative profiling of selective Sox/POU pairing on hundreds of sequences in parallel by Coop-seq.
Chang Y.K., Srivastava Y., Hu C., Joyce A., Yang X., Zuo Z., Havranek J.J., Stormo G.D., and Jauch R. (2017) “Quantitative profiling of selective Sox/POU pairing on hundreds of sequences in parallel by Coop-seq.” Nucleic Acids Res. 2017 Jan 25;45(2):832-845. doi: 10.1093/nar/gkw1198. Epub 2016 Dec 2. (Abstract)