Category: All Publications

Mechanistic and structural insight into the functional dichotomy between IL-2 and IL-15

Ring, A.M., Lin, J., Feng, D., Mitra, S., Rickert, M., Bowman, G.R., Pande, V.S., Li, P, Moraga, I., Spolski, R., Özkan, E.,Leonard, W.J. and Garcia, K.C.
Mechanistic and structural insight into the functional dichotomy between IL-2 and IL-15
Nature Immunology 13:1187-1195. (2012). (Abstract)

The primary and secondary translocase activities within E. coli RecBC helicase are tightly coupled to ATP hydrolysis by the RecB motor.

Wu C.G., Xie F., & Lohman T.M. (2012). “The primary and secondary translocase activities within E. coli RecBC helicase are tightly coupled to ATP hydrolysis by the RecB motor.” J Mol Biol. 2012 Oct 26;423(3):303-14. doi: 10.1016/j.jmb.2012.07.009. Epub 2012 Jul 20. (Abstract)

Inhibitory signaling through signal regulatory protein-α is not sufficient to explain the antitumor activities of CD47 antibodies.

Soto-Pantoja D.R., Miller T.W., Frazier W.A., & Roberts D.D. (2012). “Inhibitory signaling through signal regulatory protein-α is not sufficient to explain the antitumor activities of CD47 antibodies.” Proc Natl Acad Sci U S A. 2012 Oct 16;109(42):E2842; author reply E2844-5. doi: 10.1073/pnas.1205441109. Epub 2012 Aug 24. (Abstract)

Myosin IC generates power over a range of loads via a new tension-sensing mechanism.

Greenberg M.J., Lin T., Goldman Y.E., Shuman H., & Ostap E.M. (2012). “Myosin IC generates power over a range of loads via a new tension-sensing mechanism.” Proc Natl Acad Sci U S A. 2012 Sep 11;109(37):E2433-40. doi: 10.1073/pnas.1207811109. Epub 2012 Aug 20. (Abstract)