Category: All Publications

Structure-based drug design and optimization of mannoside bacterial FimH antagonists.

Han, Z., Pinkner, J.S., Ford, B., Obermann, R., Nolan, W., Wildman, S.A., Hobbs, D., Ellenberger, T., Cusumano, C.K., Hultgren, S.J. and Janetka, J.W.
Structure-based drug design and optimization of mannoside bacterial FimH antagonists.
J Med Chem. 53(12):4779-92. doi: 10.1021/jm100438s. (2010) (Abstract)

Substoichiometric inhibition of Abeta(1-40) aggregation by a tandem Abeta(40-1-Gly8-1-40) peptide.

Mustafi S.M., Garai K., Crick S.L., Baban B., & Frieden C. (2010). “Substoichiometric inhibition of Abeta(1-40) aggregation by a tandem Abeta(40-1-Gly8-1-40) peptide.” Biochem Biophys Res Commun. 2010 Jul 2;397(3):509-12. doi: 10.1016/j.bbrc.2010.05.144. Epub 2010 May 31. (Abstract)

Regulation of single-stranded DNA binding by the C termini of Escherichia coli single-stranded DNA-binding (SSB) protein.

Kozlov A.G., Cox M.M., and Lohman T.M. (2010) “Regulation of single-stranded DNA binding by the C termini of Escherichia coli single-stranded DNA-binding (SSB) protein.” J Biol Chem. 2010 May 28;285(22):17246-52. doi: 10.1074/jbc.M110.118273. Epub 2010 Apr 1. (Abstract)

E. coli SSB tetramer binds the first and second molecules of (dT)(35) with heat capacities of opposite sign.

Kozlov A.G. & Lohman T.M. (2010). “E. coli SSB tetramer binds the first and second molecules of (dT)(35) with heat capacities of opposite sign.” Biophys Chem. 2011 Nov;159(1):48-57. doi: 10.1016/j.bpc.2011.05.005. Epub 2011 May 12. (Abstract)

Binding specificity of Escherichia coli single-stranded DNA binding protein for the chi subunit of DNA pol III holoenzyme and PriA helicase.

Kozlov A.G., Jezewska M.J., Bujalowski W., and Lohman T.M. (2010) “Binding specificity of Escherichia coli single-stranded DNA binding protein for the chi subunit of DNA pol III holoenzyme and PriA helicase.” Biochemistry. 2010 May 4;49(17):3555-66. doi: 10.1021/bi100069s. (Abstract)