Category: All Publications

A joint x-ray and neutron study on amicyanin reveals the role of protein dynamics in electron transfer.

Sukumar N., Mathews F.S., Langan P., & Davidson V.L. (2010). “A joint x-ray and neutron study on amicyanin reveals the role of protein dynamics in electron transfer.” Proc Natl Acad Sci U S A. 2010 Apr 13;107(15):6817-22. doi: 10.1073/pnas.0912672107. Epub 2010 Mar 29. (Abstract)

Parallel multiplicative target screening against divergent bacterial replicases: identification of specific inhibitors with broad spectrum potential.

Dallmann, H.G., Fackelmayer, O.J., Tomer, G., Chen, J., Wiktor-Becker, A., Ferrara, T., Pope, C., Oliveira, M.T., Burgers, P.M., Kaguni, L.S. and McHenry, C.S.
Parallel multiplicative target screening against divergent bacterial replicases: identification of specific inhibitors with broad spectrum potential.
Biochemistry. 49:2551-2562 (2010). (Abstract)

Using ligand-based virtual screening to allosterically stabilize the activated state of a GPCR.

Taylor C.M., Rockweiler N.B., Liu C., Rikimaru L., Tunemalm A.K., Kisselev O.G., and Marshall G.R. (2010) “Using ligand-based virtual screening to allosterically stabilize the activated state of a GPCR.” Chem Biol Drug Des. 2010 Mar;75(3):325-32. doi: 10.1111/j.1747-0285.2009.00944.x. Epub 2010 Jan 19. (Abstract)

Direct DNA amplification from crude clinical samples using a PCR enhancer cocktail and novel mutants of Taq.

Zhang Z., Kermekchiev M.B., & Barnes W.M. (2010). “Direct DNA amplification from crude clinical samples using a PCR enhancer cocktail and novel mutants of Taq.” J Mol Diagn. 2010 Mar;12(2):152-61. doi: 10.2353/jmoldx.2010.090070. Epub 2010 Jan 14. (Abstract)

The XPA-binding domain of ERCC1 is required for nucleotide excision repair but not other DNA repair pathways.

Orelli, B., McClendon, T.B., Tsodikov, O.V., Ellenberger, T., Niedernhofer, L.J. and Scharer, O.D.
The XPA-binding domain of ERCC1 is required for nucleotide excision repair but not other DNA repair pathways.
J Biol Chem 285:3705-3712 (2010). (Abstract)

Whole cell mechanics of contractile fibroblasts: relations between effective cellular and extracellular matrix moduli.

Marquez J.P., Elson E.L., & Genin G.M. (2010). “Whole cell mechanics of contractile fibroblasts: relations between effective cellular and extracellular matrix moduli.” Philos Trans A Math Phys Eng Sci. 2010 Feb 13;368(1912):635-54. doi: 10.1098/rsta.2009.0240. (Abstract)

Analysis of protein expression regulated by the Helicobacter pylori ArsRS two-component signal transduction system.

Loh J.T., Gupta S.S., Friedman D.B., Krezel A.M., & Cover T.L. (2010). “Analysis of protein expression regulated by the Helicobacter pylori ArsRS two-component signal transduction system.” J Bacteriol. 2010 Apr;192(8):2034-43. doi: 10.1128/JB.01703-08. Epub 2010 Feb 12. (Abstract)

CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer.

Stewart C.R., Stuart L.M., Wilkinson K., van Gils J.M., Deng J., Halle A., Rayner K.J., Boyer L., Zhong R., Frazier W.A., Lacy-Hulbert A., Khoury J.E., Golenbock D.T., & Moore K.J. (2010). “CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer.” Nat Immunol. 2010 Feb;11(2):155-61. doi: 10.1038/ni.1836. Epub 2009 Dec 27. (Abstract)