Category: 2022 Research Awards

Molecular determinants of evolutionary conservation in disordered protein regions

Oct 1st 2022 – Alex Holehouse, assistant professor of biochemistry and molecular has received $380,000 in funding from the Human Frontiers Science Program (HFSP) to lead a three-year project titled “Molecular determinants of evolutionary conservation in disordered protein regions”. This project will integrate computational and experimental approaches to uncover who intrinsically disordered protein regions evolve. The proposal involves co-investigators Dr. Hyun Kate Lee (University of Toronto, CA) and Dr. Dolf Weijers (Wageningen University, NL).

Molecular engineering to understand desiccation protection and water responsiveness.

Oct 1st 2022 – Alex Holehouse, assistant professor of biochemistry and molecular has received more than $450,000 in funding from the National Science Foundation (NSF) to lead a five-year project titled “Molecular engineering to understand desiccation protection and water responsiveness.” The project is part of a larger grant called “Life without water: protecting macromolecules, cells, and organisms during desiccation and rehydration across kingdoms of life.” This grant establishes the Water and Life Interface Institute led by Carnegie Science (https://www.walii.science/). The new initiative includes collaborators from at least nine research institutions nationwide.

Quantitative mass spectrometry for comprehending epigenetic mechanisms in a new underlying neurological developmental disorder

August 16th, 2022 – Benjamin Garcia, PhD, Raymond H. Wittcoff Distinguished Professor and Head of Biochemistry and Molecular Biophysics, along with Elizabeth Bhoj, MD, PhD, Assistant Professor of Pediatrics, University of Pennsylvania of Medicine and Children’s Hospital of Philadelphia received a five year grant from the National Institutes of Health for their research entitled “Quantitative mass spectrometry for comprehending epigenetic mechanisms in a new underlying neurological developmental disorder”.

Human heart-on-a-chip to study the immune system in cardiac disease pathogenesis and repair

July 1st, 2022 – Michael Greenberg, PhD, Associate Professor of Biochemistry and Molecular Biophysics along with Kory J. Lavine, MD PhD, Associate Professor of Medicine and Nathaniel D. Huebsch, PhD, Assistant Professor of Biomedical Engineering have received a new three-year grant award from American Heart Association for their research entitled “Human heart-on-a-chip to study the immune system in cardiac disease pathogenesis and repair”.

A multipronged investigation of SARS-CoV-2 genome packaging

April 22nd, 2022 – Andrea Soranno, PhD, Assistant Professor of Biochemistry and Molecular Biophysics along with Kathleen Hall, PhD, Professor of Biochemistry and Molecular Biophysics and Alex Holehouse, PhD, Assistant Professor of Biochemistry and Molecular Biophysics have received a new five-year grant from National Institute of Allergy and Infectious Diseases for their research entitled “A multipronged investigation of SARS-CoV-2 genome packaging”

Molecular determinants of evolutionary conservation in disordered protein regions

March 16th, 2022 – Alex Holehouse, PhD, Assistant Professor of Biochemistry and Molecular Biophysics along with Dolf Weijer, PhD, Associate Professor in Laboratory of Biochemistry from Wageningen University and Research, and Hyun Lee, PhD, Assistant Professor of Biochemistry from University of Toronto, received a new three-year grant award from Human Frontier Science Program for their research entitled “Molecular determinants of evolutionary conservation in disordered protein regions”.

Optimizing CDPK1 inhibitors for chronic toxoplasmosis

March 1st, 2022 – Jim Janetka, PhD, Professor in Biochemistry and Molecular Biophysics and David Sibley, Professor in Molecular Microbiology received a new five-year grant R01 award from the National Institute of Allergy and Infectious Diseases (NIAID) of the NIH totaling 3.9 million dollars for their research entitled “Optimizing CDPK1 inhibitors for chronic toxoplasmosis”.