Category: Holehouse

Oct 1st 2022 – Alex Holehouse, assistant professor of biochemistry and molecular has received $380,000 in funding from the Human Frontiers Science Program (HFSP) to lead a three-year project titled “Molecular determinants of evolutionary conservation in disordered protein regions”. This project will integrate computational and experimental approaches to uncover who intrinsically disordered protein regions evolve. The proposal involves co-investigators Dr. Hyun Kate Lee (University of Toronto, CA) and Dr. Dolf Weijers (Wageningen University, NL).

Oct 1st 2022 – Alex Holehouse, assistant professor of biochemistry and molecular has received more than $450,000 in funding from the National Science Foundation (NSF) to lead a five-year project titled “Molecular engineering to understand desiccation protection and water responsiveness.” The project is part of a larger grant called “Life without water: protecting macromolecules, cells, and organisms during desiccation and rehydration across kingdoms of life.” This grant establishes the Water and Life Interface Institute led by Carnegie Science (https://www.walii.science/). The new initiative includes collaborators from at least nine research institutions nationwide.

March 16th, 2022 – Alex Holehouse, PhD, Assistant Professor of Biochemistry and Molecular Biophysics along with Dolf Weijer, PhD, Associate Professor in Laboratory of Biochemistry from Wageningen University and Research, and Hyun Lee, PhD, Assistant Professor of Biochemistry from University of Toronto, received a new three-year grant award from Human Frontier Science Program for their research entitled “Molecular determinants of evolutionary conservation in disordered protein regions”.

October 22nd, 2021 – Alex Holehouse, PhD, Assistant Professor of Biochemistry and Molecular Biophysics, received a one year renewal grant award from Longer Life Foundation for his research entitled “Predicting the functional impact of genetic variation within intrinsically disordered protein regions”.

August 18th, 2021 – Alex Holehouse, PhD, Assistant Professor of Biochemistry and Molecular Biophysics, along with Shahar Sukenik, Assistant Professor, Department of Chemistry & Biochemistry at University of California, Merced, and Thomas Boothby, Assistant Professor, Department of Molecular Biology, University of Wyoming, received a new four year grant award from the National Science Foundation through the new “Integrative Research in Biology” mechanism for their research entitled “Collaborative Research: Functional Synergy Between Disordered Proteins and their Environment in Desiccation Protection”.

January 11th, 2021 – Alex Holehouse, Ph.D., Assistant Professor of Biochemistry and Molecular Biophysics, received a new one year grant award from Dewpoint Therapeutics for his research entitled “Bioinformatic tools for the analysis of phase separating proteins”.

October 6th, 2020 – Alex Holehouse, PhD, Assistant Professor of Biochemistry and Molecular Biophysics, received a new one year grant award from Longer Life Foundation for his research entitled “Predicting the functional impact of genetic variation within intrinsically disordered protein regions”