January 28th, 2024 – Alex Holehouse, PhD, Assistant Professor in the Department of Biochemistry and Molecular Biophysics, received an NSF CAREER award. This five-year award from the National Science Foundation, is entitled “Evolutionary Principles of Intrinsically Disordered Proteins.”
January 1st, 2024 – Alex Holehouse, PhD Assistant Professor in the Department of Biochemistry and Molecular Biophysics, along with Joe Corbo, MD, PhD, in the Department of Pathology and Immunology, received a new two-year grant award from the Hope Center entitled “Targeting a transcriptional co-repressor to prevent photoreceptor degeneration.”
September 1st, 2023 – Alex Holehouse, PhD, Assistant Professor in the Department of Biochemistry and Molecular Biophysics, received a 2023 NIH New Innovator Award. This five-year award from the National Institute of Health, administered through the National Cancer Institute, is entitled “Uncovering the regulatory logic of gene expression encoded by disordered regions.”.
Oct 1st 2022 – Alex Holehouse, assistant professor of biochemistry and molecular has received $380,000 in funding from the Human Frontiers Science Program (HFSP) to lead a three-year project titled “Molecular determinants of evolutionary conservation in disordered protein regions”. This project will integrate computational and experimental approaches to uncover who intrinsically disordered protein regions evolve. The proposal involves co-investigators Dr. Hyun Kate Lee (University of Toronto, CA) and Dr. Dolf Weijers (Wageningen University, NL).
Oct 1st 2022 – Alex Holehouse, assistant professor of biochemistry and molecular has received more than $450,000 in funding from the National Science Foundation (NSF) to lead a five-year project titled “Molecular engineering to understand desiccation protection and water responsiveness.” The project is part of a larger grant called “Life without water: protecting macromolecules, cells, and organisms during desiccation and rehydration across kingdoms of life.” This grant establishes the Water and Life Interface Institute led by Carnegie Science (https://www.walii.science/). The new initiative includes collaborators from at least nine research institutions nationwide.
April 22nd, 2022 – Andrea Soranno, PhD, Assistant Professor of Biochemistry and Molecular Biophysics along with Kathleen Hall, PhD, Professor of Biochemistry and Molecular Biophysics and Alex Holehouse, PhD, Assistant Professor of Biochemistry and Molecular Biophysics have received a new five-year grant from National Institute of Allergy and Infectious Diseases for their research entitled “A multipronged investigation of SARS-CoV-2 genome packaging”
March 16th, 2022 – Alex Holehouse, PhD, Assistant Professor of Biochemistry and Molecular Biophysics along with Dolf Weijer, PhD, Associate Professor in Laboratory of Biochemistry from Wageningen University and Research, and Hyun Lee, PhD, Assistant Professor of Biochemistry from University of Toronto, received a new three-year grant award from Human Frontier Science Program for their research entitled “Molecular determinants of evolutionary conservation in disordered protein regions”.
October 22nd, 2021 – Alex Holehouse, PhD, Assistant Professor of Biochemistry and Molecular Biophysics, received a one year renewal grant award from Longer Life Foundation for his research entitled “Predicting the functional impact of genetic variation within intrinsically disordered protein regions”.
August 18th, 2021 – Alex Holehouse, PhD, Assistant Professor of Biochemistry and Molecular Biophysics, along with Shahar Sukenik, Assistant Professor, Department of Chemistry & Biochemistry at University of California, Merced, and Thomas Boothby, Assistant Professor, Department of Molecular Biology, University of Wyoming, received a new four year grant award from the National Science Foundation through the new “Integrative Research in Biology” mechanism for their research entitled “Collaborative Research: Functional Synergy Between Disordered Proteins and their Environment in Desiccation Protection”.
April 15th, 2021 – Linda J. Pike, PhD, Professor of Biochemistry and Molecular Biophysics, along with Alexander S. Holehouse, PhD, Assistant Professor of Biochemistry and Molecular Biophysics, and Gary J. Patti, PhD, Professor of Chemistry and of Genetics and Medicine, received a new four year grant award from the National Institute of General Medical Sciences for their research entitled “Intrinsic Disorder and Agonist Bias in EGF Receptor Signaling”.