Category: 2021 Research Awards

Collaborative Research: MFB: Deciphering the Logic of PTM Crosstalk via Novel Chemical Technology: Histones and Beyond

August 16th, 2021 – Benjamin Garcia, PhD, Raymond H. Wittcoff Distinguished Professor and Head of Biochemistry and Molecular Biophysics, along with Philip A Cole, MD, PhD, Professor Biological Chemistry & Molecular Pharmacology at Harvard Medical School, received a new three year grant award from The National Science Foundation for their research entitled “Collaborative Research: MFB: Deciphering the Logic of PTM Crosstalk via Novel Chemical Technology: Histones and Beyond”.

Mechanisms of DNA replication and maintenance in eukaryotes

May 14th, 2021 – Peter M. Burgers, PhD, Marvin A. Brennecke Professor of Biological Chemistry, department of biochemistry and molecular biophysics was awarded a five-year MIRA grant renewal from the National Institute of General Medical Sciences for his research entitled “Mechanisms of DNA replication and maintenance in eukaryotes”.

Intrinsic Disorder and Agonist Bias in EGF Receptor Signaling

April 15th, 2021 – Linda J. Pike, PhD, Professor of Biochemistry and Molecular Biophysics, along with Alexander S. Holehouse, PhD, Assistant Professor of Biochemistry and Molecular Biophysics, and Gary J. Patti, PhD, Professor of Chemistry and of Genetics and Medicine, received a new four year grant award from the National Institute of General Medical Sciences for their research entitled “Intrinsic Disorder and Agonist Bias in EGF Receptor Signaling”.

Development of small molecule inhibitors of metabolic enzymes as broad-spectrum anthelmintic drugs

March 18th, 2021 – Jim Janetka, PhD, Professor of Biochemistry and Molecular Biophysics, Makedonka Mitreva, Professor of Medicine and Genetics, and Raffi Aroian, Professor of Molecular Medicine at the University of Massachusetts Medical School have received a new multi-PI R01 award from the National Institutes of Health, National Institute of Allergy and Infectious Diseases entitled “Development of small molecule inhibitors of metabolic enzymes as broad-spectrum anthelmintic drugs”.

Innovative Strategies to Combat Antibiotic-resistant Infections

March 17th, 2021 – Jim Janetka, PhD, Professor of Biochemistry and Molecular Biophysics, along with Scott Hultgren, Helen L. Stoever Professor of Molecular Microbiology, Michael Caparon, Professor of Molecular Microbiology, Peng Yuan, Associate Professor of Cell Biology and Physiology, and Ali Ellebedy, Associate Professor of Pathology and Immunology received a five-year U19 Research Program–Cooperative Agreement Award from the National Institutes of Health, National Institute of Allergy and Infectious Diseases entitled “Innovative Strategies to Combat Antibiotic-resistant Infections”. Dr. Janetka is leader of the project scientific core named “Rational Design and Synthesis of Small Molecule Inhibitors Targeting Unique Pathogenic Mechanisms in Gram- and Gram+ Bacteria Important in UTI”.

The role of the mitochondrial phosphatase Pptc7 in enabling metabolic flexibility

February 9th, 2021 – Natalie M. Niemi, PhD, Assistant Professor in the department of Biochemistry and Molecular Biophysics, received a one-year pilot and feasibility grant award from the Washington University Diabetes Research Center (DRC), sponsored by the National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) for her research entitled “The role of the mitochondrial phosphatase Pptc7 in enabling metabolic flexibility”.

Multiscale investigation of cardiomyopathy-associated mutations in metavinculin

February 2nd, 2021 – Samantha Kirstin Barrick, PhD, Postdoctoral Scholar in the department of Biochemistry and Molecular Biophysics, and the laboratory of Dr. Michael J. Greenberg, PhD, received a new three year fellowship award from the National Institutes of Health, National Heart, Lung, and Blood Institute for her research entitled “Multiscale investigation of cardiomyopathy-associated mutations in metavinculin”.

Interdisciplinary structural studies of iron homeostasis in cardiovascular health

January 22nd, 2021 – Weikai Li, PhD, Associate Professor of Biochemistry and Molecular Biophysics, along with Michael L. Gross, PhD, Professor of Chemistry, Immunology, and Medicine, and Michael J. Greenberg, PhD, Assistant Professor of Biochemistry and Molecular Biophysics, received a new three-year grant award from American Heart Association for their research entitled “Interdisciplinary structural studies of iron homeostasis in cardiovascular health”.