Category: 2021 Research Awards

Predicting the functional impact of genetic variation within intrinsically disordered protein regions

October 22nd, 2021 – Alex Holehouse, PhD, Assistant Professor of Biochemistry and Molecular Biophysics, received a one year renewal grant award from Longer Life Foundation for his research entitled “Predicting the functional impact of genetic variation within intrinsically disordered protein regions”.

Integrative approach for accelerating filarial worm drug discovery to treat river blindness

September 30th, 2021 – Jim Janetka, PhD, Professor of Biochemistry and Molecular Biophysics, Makedonka Mitreva, Professor of Medicine and Genetics, and Sara Lustigman, Professor and Head, Laboratory of Molecular Parasitology Member, Lindsley F. Kimball Research Institute, New York Blood Center have received a new multi-PI R01 award from the National Institutes of Health, National Eye Institute entitled “Integrative approach for accelerating filarial worm drug discovery to treat river blindness”.

Functions of DNA helicases at hard-to-replicate sites and telomere regulation

September 17th, 2021 – Roberto Galletto, PhD, Associate Professor in the department of biochemistry and molecular biophysics was awarded a new five year MIRA grant from the National Institute of General Medical Sciences for his research entitled “Functions of DNA helicases at hard-to-replicate sites and telomere regulation”.

Investigating the molecular grammar driving the assembly of membraneless-organelles

September 15th, 2021 – Daniel Griffith, BS, Pre-Doc Trainee in the department of Biochemistry and Molecular Biophysics, and the laboratory of Alex Holehouse, PhD, received a new three-year Graduate Research Fellowship award from the National Science Foundation for his research entitled “Investigating the molecular grammar driving the assembly of membraneless-organelles”.

Viral modulation of epitranscriptomic mechanisms

August 24th, 2021 – Benjamin Garcia, PhD, Raymond H. Wittcoff Distinguished Professor and Head of Biochemistry and Molecular Biophysics, along with Matthew D. Weitzman, PhD, Professor of Microbiology, Professor of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine and Children’s Hospital of Philadelphia, received a five year grant renewal from the National Institute of Allergy and Infectious Diseases for their research entitled “Viral modulation of epitranscriptomic mechanisms”.

Single Molecule Biophysics of Intrinsically Disordered Proteins in Disease

August 23rd, 2021 – Jhullian Jamille Alston, BA, Pre-Doc Trainee in the department of Biochemistry and Molecular Biophysics, and the laboratories of Alex Holehouse, PhD and Andrea Soranno, PhD, received a Predoctoral to Postdoctoral Fellow Transition Award from the National Cancer Institute for his research entitled “Single Molecule Biophysics of Intrinsically Disordered Proteins in Disease”.

Collaborative Research: Functional Synergy Between Disordered Proteins and their Environment in Desiccation Protection

August 18th, 2021 – Alex Holehouse, PhD, Assistant Professor of Biochemistry and Molecular Biophysics, along with Shahar Sukenik, Assistant Professor, Department of Chemistry & Biochemistry at University of California, Merced, and Thomas Boothby, Assistant Professor, Department of Molecular Biology, University of Wyoming, received a new four year grant award from the National Science Foundation through the new “Integrative Research in Biology” mechanism for their research entitled “Collaborative Research: Functional Synergy Between Disordered Proteins and their Environment in Desiccation Protection”.

Leveraging protein dynamics to drug filovirus protein-nucleic acid interactions using simulations and experiments

August 17th, 2021 – Matthew A Cruz, BS, Pre-Doc Trainee in the department of Biochemistry and Molecular Biophysics, and the laboratory of Gregory Bowman, PhD, received a new three-year fellowship award from the National Institutes of Health, National Institute of Allergy and Infectious Diseases for his research entitled “Leveraging protein dynamics to drug filovirus protein-nucleic acid interactions using simulations and experiments”.

ApoE isoform-specific structure: insights on biology and pathobiology

August 17th, 2021 – Andrea Soranno, PhD, Assistant Professor of Biochemistry and Molecular Biophysics, Carl Frieden, PhD, Professor of Biochemistry and Molecular Biophysics, and Rui Zhang, PhD, Assistant Professor of Biochemistry and Molecular Biophysics will collaborate in the Project named “ApoE isoform-specific structure: insights on biology and pathobiology”. The Project is part of the newly awarded five-year U19 Research Program from the National Institutes of Health, National Institute of Aging, entitled “Biology and pathobiology of apoE in aging and Alzheimer’s disease”, helmed by Dr. David Holtzman, Professor and Chair of the Department of Neurology at Washington University, in St Louis, and Dr. Guojun Bu, Professor of Medicine and Chair of the Department of Neuroscience, Mayo Clinic.

Biology and pathobiology of apoE in aging and Alzheimer’s disease

August 17th, 2021 – Greg Bowman, PhD, Associate Professor of Biochemistry and Molecular Biophysics, along with Guojun Bu, Professor of Medicine and chair of the Department of Neuroscience, Mayo Clinic, received a five-year U19 Research Program – Cooperative Agreement Award from the National Institutes of Health, National Institute on Aging, entitled “Biology and pathobiology of apoE in aging and Alzheimer’s disease”. Dr. Bowman is leader of the project’s biochemical & structural biology core.