Author: Nicholas Caito

The Mutation R94C InTNNT2-encoded Troponin T Predisposes to Restrictive Cardiomyopathy and Pediatric Sudden Death Through Impaired Thin Filament Relaxation Resulting in Myocardial Diastolic Dysfunction

Jordan E Ezekian, Sarah R Clippinger, Jackie Garcia, Susan W Denfield, Aamir Jeewa, William Dreyer, Wenxin Zou, Yuxin Fan, Hugh D Allen, Jeffrey Kim, Michael Greenberg, & Andrew P Landstrom (2019). “The Mutation R94C InTNNT2-encoded Troponin T Predisposes to Restrictive Cardiomyopathy and Pediatric Sudden Death Through Impaired Thin Filament Relaxation Resulting in Myocardial Diastolic Dysfunction” American Heart Association, Inc. 11 Nov 2019, Circulation. 2019;140:A12139 (Abstract)

Dr. Frieden Mentioned

Dr. Carl FriedenNovember 4th, 2019 – Research by Dr. Carl Frieden appeared on the Alzforum site in the article “Can an ApoE Mutation Halt Alzheimer’s Disease?”

One of Dr. Frieden’s previous publications was also cited by the article.

Click here to view the article on the Alzform site.

To view Dr. Frieden’s publication mentioned in the article, you can click here to view it on the NIH site.

Cryo-EM Structure of Nucleotide-Bound Tel1ATM Unravels the Molecular Basis of Inhibition and Structural Rationale for Disease-Associated Mutations.

Yates L.A., Williams R.M., Hailemariam S., Ayala R., Burgers P., & Zhang X. (2019). “Cryo-EM Structure of Nucleotide-Bound Tel1ATM Unravels the Molecular Basis of Inhibition and Structural Rationale for Disease-Associated Mutations.” Structure. 2019 Nov 4. pii: S0969-2126(19)30353-3. doi: 10.1016/j.str.2019.10.012. [Epub ahead of print] (Abstract)