Cryo-EM studies of molecular motors and their associated filamentous assemblies
2019-10-29 – Charles Sindelar, Ph.D. – Yale University – “Cryo-EM studies of molecular motors and their associated filamentous assemblies” (more…)
Author: Nicholas Caito
Regulation of Nearest-neighbor cooperative binding of E. coli SSB protein to DNA
Alexander G. Kozlov, Min Kyung Shinn, & Timothy M. Lohman (2019). “Regulation of Nearest-neighbor cooperative binding of E. coli SSB protein to DNA” Biophysical Journal. 28 October 2019. doi.org/10.1016/j.bpj.2019.09.047 (Abstract)
Structure of the Decorated Ciliary Doublet Microtubule
Meisheng Ma, Mihaela Stoyanova, Griffin Rademacher, Susan K. Dutcher, Alan Brown, & Rui Zhang (2019). “Structure of the Decorated Ciliary Doublet Microtubule” Cell. Volume 179, Issue 4, 31 October 2019, Pages 909-922.e12. doi: 10.1016/j.cell.2019.09.030 (Abstract)
A novel chlorophyll protein complex in the repair cycle of photosystem II.
Weisz D.A., Johnson V.M., Niedzwiedzki D.M., Shinn M.K., Liu H., Klitzke C.F., Gross M.L., Blankenship R.E., Lohman T.M., & Pakrasi H.B. (2019). “A novel chlorophyll protein complex in the repair cycle of photosystem II.” Proc Natl Acad Sci U S A. 2019 Oct 22;116(43):21907-21913. doi: 10.1073/pnas.1909644116. Epub 2019 Oct 8. (Abstract)
The telomere-binding protein Rif2 and ATP-bound Rad50 have opposing roles in the activation of yeast Tel1ATM kinase.
Hailemariam S., De Bona P., Galletto R., Hohl M., Petrini J.H., & Burgers P.M. (2019). “The telomere-binding protein Rif2 and ATP-bound Rad50 have opposing roles in the activation of yeast Tel1ATM kinase.” J Biol Chem. 2019 Oct 22. pii: jbc.RA119.011077. doi: 10.1074/jbc.RA119.011077. [Epub ahead of print] (Abstract)
Evolution and Gene Expression One Cell at a Time
2019-10-22 – David Gresham, Ph.D. – New York University – “Evolution and Gene Expression One Cell at a Time” (more…)
Tracking proton transfer in beta-lactamase catalysis using ultrahigh resolution X- ray crystallography
2019-10-15 – Yu Chen, Ph.D. – University of South Florida – “Tracking proton transfer in beta-lactamase catalysis using ultrahigh resolution X- ray crystallography” (more…)
Molecular choreography of the RPA-DNA-RAD52 complex during DNA replication, recombination and repair
2019-10-01 – Maria Spies, Ph.D. – University of Iowa – “Molecular choreography of the RPA-DNA-RAD52 complex during DNA replication, recombination and repair” (more…)
2019 Elliot Elson Fellowship Seminar
On September 20th, 2019, the department held a special seminar to recognize the recipient of the 2018 Elliot Elson Fellowship. Ms. Sarah Clippinger shared her research on “Dissecting the Molecular and Cellular Mechanisms of Familial Cardiomyopathy”. For more information on Sarah, please click here.
You can click here to view photos from the event.
Inhibitors of pro-HGF activation overcome resistance to anti-EGFR therapy
September 16th, 2019 – Jim Janetka, PhD, Associate Professor of Biochemistry and Molecular Biophysics, and Co-Founder of ProteXase Therapeutics, Inc., along with Lidija Klampfer, PhD, Co-Founder and Chief Scientific Officer of ProteXase Therapeutics, Inc., received a one-year SBIR grant award from the National Cancer Institute for their research entitled “Inhibitors of pro-HGF activation overcome resistance to anti-EGFR therapy”.