Author: Nicholas Caito

Structural Mechanisms of Cooperative DNA Binding by Bacterial Single-Stranded DNA-Binding Proteins

Katarzyna Dubiel, Angela R. Myers, Alexander G. Kozlov, Olivia Yang, Jichuan Zhang, Taekjip Ha, Timothy M. Lohman, & James L. Keck (2019). “Structural Mechanisms of Cooperative DNA Binding by Bacterial Single-Stranded DNA-Binding Proteins” J Mol Biol. 2019 Jan 18;431(2):178-195. doi: 10.1016/j.jmb.2018.11.019. Epub 2018 Nov 22. (Abstract)

Effects of α-tubulin acetylation on microtubule structure and stability

Lisa Eshun-Wilson, Rui Zhang, Didier Portran, Maxence Nachury, Daniel Toso, Thomas Lohr, Michelle Vendruscolo, Massimiliano Bonomi, James Fraser, & Eva Nogales (2019). “Effects of α-tubulin acetylation on microtubule structure and stability” bioRxiv. January 09, 2019. doi.org/10.1101/516591. (Abstract)

2018 BMB Holiday Party

CooperOn December 8th, 2018, the BMB Department celebrated its annual Holiday Party at Saratoga Lanes in Maplewood, MO. Everyone enjoyed bowling, pool and a visit from Santa.

Click on the following to view more photos or a slideshow of the photos taken at the event.

Hepatocyte growth factor activator inhibitor-2 stabilizes Epcam and maintains epithelial organization in the mouse intestine.

Kawaguchi M., Yamamoto K., Takeda N., Fukushima T., Yamashita F., Sato K., Kitamura K., Hippo Y., Janetka J.W., & Kataoka H. (2019). “Hepatocyte growth factor activator inhibitor-2 stabilizes Epcam and maintains epithelial organization in the mouse intestine.” Commun Biol. 2019 Jan 4;2:11. doi: 10.1038/s42003-018-0255-8. eCollection 2019. (Abstract)

2018 David F. Silbert Summer Fellowship

Congratulations to John LeClair and Meng’ou (Mary) Zhu for receiving the 2018 David F. Silbert Summer Fellowship Award.

John LeClair worked with Drs. Lisa D McKenzie and Milan G Chheda on a project entitled “Characterizing the role of CHD4 in glioblastoma treatment response”, and Meng’ou (Mary) Zhu worked with Drs. Matthew J Walter and Michael O Alberti on a project entitled “Mutant U2AF1(Q157P) expression alters hematopoiesis in vivo.” (more…)

Terminal coupling enabled structure determination of human membrane proteins at atomic resolution

December 27th, 2018 – Weikai Li, PhD, assistant professor of biochemistry and molecular biophysics, along with Rui Zhang, PhD, assistant professor of biochemistry and molecular biophysics received a new three year, grant award from the W. M. Keck foundation for their research entitled “Terminal coupling enabled structure determination of human membrane proteins at atomic resolution”.